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IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

The Journal of biological chemistry, 2016-12, Vol.291 (51), p.26364-26376

2016

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The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration

The Journal of biological chemistry, 2011-10, Vol.286 (40), p.35119-35128

2011

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Neurofibromatosis Type I Tumor Suppressor Neurofibromin Regulates Neuronal Differentiation via Its GTPase-activating Protein Function toward Ras

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26958-26969

2003

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GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.9891-9900

2006

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Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity

The Journal of biological chemistry, 2003-01, Vol.278 (5), p.2807-2818

2003

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Mechanical Inhibition of RANKL Expression Is Regulated by H-Ras-GTPase

The Journal of biological chemistry, 2006-01, Vol.281 (3), p.1412-1418

2006

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Engineering the Phosphoinositide-binding Profile of a Class I Pleckstrin Homology Domain

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.39489-39496

2003

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Biochemical Characterization of Rab3-GTPase-activating Protein Reveals a Mechanism Similar to That of Ras-GAP

The Journal of biological chemistry, 2000-10, Vol.275 (41), p.31786-31791

2000

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The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

The Journal of biological chemistry, 2006-02, Vol.281 (8), p.4903-4910

2006

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Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras

The Journal of biological chemistry, 2002-11, Vol.277 (45), p.43024-43032

2002

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Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1

The Journal of biological chemistry, 2016-02, Vol.291 (7), p.3124-3134

2016

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Multiple ras effector pathways contribute to G(1) cell cycle progression

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.22033-22040

1999

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3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.21926-21931

1999

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Identification of a Novel Guanine Nucleotide Exchange Factor for the Rho GTPase

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25452-25458

1996

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Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domains

The Journal of biological chemistry, 1997-08, Vol.272 (35), p.21999-22007

1997

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Neurofibromin GTPase-activating Protein-related Domains Restore Normal Growth in Nf1−/− Cells

The Journal of biological chemistry, 2001-03, Vol.276 (10), p.7240-7245

2001

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The Ras-related GTPase Rac1 Binds Tubulin (∗)

The Journal of biological chemistry, 1996-02, Vol.271 (7), p.3756-3762

1996

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Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)

The Journal of biological chemistry, 1990-11, Vol.265 (33), p.20437-20442

1990

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Biochemical Analysis of SopE from Salmonella typhimurium, a Highly Efficient Guanosine Nucleotide Exchange Factor for RhoGTPases

The Journal of biological chemistry, 1999-10, Vol.274 (43), p.30501-30509

1999

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Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9165-9168

1993

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A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p21rac-GTPase activating protein n-chimaerin

The Journal of biological chemistry, 1993-05, Vol.268 (15), p.10709-10712

1993

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Post-translational Modification of H-Ras Is Required for Activation of, but Not for Association with, B-Raf

The Journal of biological chemistry, 1996-03, Vol.271 (9), p.4671-4678

1996

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Involvement of the Switch 2 Domain of Ras in Its Interaction with Guanine Nucleotide Exchange Factors (∗)

The Journal of biological chemistry, 1996-05, Vol.271 (19), p.11076-11082

1996

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Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9410-9415

1993

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Individual epidermal growth factor receptor autophosphorylation sites do not stringently define association motifs for several SH2-containing proteins

The Journal of biological chemistry, 1994-04, Vol.269 (16), p.12320-12324

1994

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IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration

Neurofibromatosis Type I Tumor Suppressor Neurofibromin Regulates Neuronal Differentiation via Its GTPase-activating Protein Function toward Ras

GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins

Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity

Mechanical Inhibition of RANKL Expression Is Regulated by H-Ras-GTPase

Engineering the Phosphoinositide-binding Profile of a Class I Pleckstrin Homology Domain

Biochemical Characterization of Rab3-GTPase-activating Protein Reveals a Mechanism Similar to That of Ras-GAP

The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras

Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1

Multiple ras effector pathways contribute to G(1) cell cycle progression

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

Identification of a Novel Guanine Nucleotide Exchange Factor for the Rho GTPase

Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domains

Neurofibromin GTPase-activating Protein-related Domains Restore Normal Growth in Nf1−/− Cells

The Ras-related GTPase Rac1 Binds Tubulin (∗)

Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)

Biochemical Analysis of SopE from Salmonella typhimurium, a Highly Efficient Guanosine Nucleotide Exchange Factor for RhoGTPases

Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger

A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p21rac-GTPase activating protein n-chimaerin

Post-translational Modification of H-Ras Is Required for Activation of, but Not for Association with, B-Raf

Involvement of the Switch 2 Domain of Ras in Its Interaction with Guanine Nucleotide Exchange Factors (∗)

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor

Individual epidermal growth factor receptor autophosphorylation sites do not stringently define association motifs for several SH2-containing proteins

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