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Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (2), p.652-657

2014

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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (35), p.12853-12858

2014

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Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.E4869-E4877

2014

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Protein conformational dynamics in the mechanism of HIV-1 protease catalysis

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (52), p.20982-20987

2011

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Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (36), p.17825-17830

2019

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Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.19914-19925

2020

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Structure and assembly of a paramyxovirus matrix protein

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (35), p.13996-14000

2012

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Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12704-12709

2012

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Structural basis for the enhanced stability of highly fluorinated proteins

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (13), p.4810-4815

2012

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Structural basis for the recruitment of glycogen synthase by glycogenin

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.E2831-E2840

2014

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Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10161-10166

2014

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Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.6509-6514

2014

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Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16107-16112

2012

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Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.6275-6280

2014

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Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.6939-6944

2011

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Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10404-10410

2014

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Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4425-4430

2012

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The Semaphorin Receptor Plexin-B1 Specifically Interacts with Active Rac in a Ligand-Dependent Manner

Proceedings of the National Academy of Sciences - PNAS, 2000-11, Vol.97 (23), p.12457-12462

2000

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Physical Reasons for the Unusual α -Helix Stabilization Afforded by Charged or Neutral Polar Residues in Alanine-Rich Peptides

Proceedings of the National Academy of Sciences - PNAS, 2000-11, Vol.97 (24), p.13075-13079

2000

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cDNA Cloning and Expression of the Human A-Type Platelet-Derived Growth Factor (PDGF) Receptor Establishes Structural Similarity to the B-Type PDGF Receptor

Proceedings of the National Academy of Sciences - PNAS, 1989-07, Vol.86 (13), p.4917-4921

1989

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Expression of an Exogenous Eukaryotic DNA Methyltransferase Gene Induces Transformation of NIH 3T3 Cells

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.8891-8895

1993

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The gene for albicidin detoxification from Pantoea dispersa encodes an esterase and attenuates pathogenicity of Xanthomonas albilineans to sugarcane

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (18), p.9984-9989

1997

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Site-Directed Mutagenesis of Amino Acid Residues of Protein Phosphatase 1 Involved in Catalysis and Inhibitor Binding

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (8), p.3530-3535

1997

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B3(Fv)-PE38KDEL, A Single-Chain Immunotoxin that Causes Complete Regression of a Human Carcinoma in Mice

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (19), p.8616-8620

1991

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Dimerization and DNA Binding Alter Phosphorylation of Fos and Jun

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (14), p.6766-6770

1993

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Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

Protein conformational dynamics in the mechanism of HIV-1 protease catalysis

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase

Structure and assembly of a paramyxovirus matrix protein

Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines

Structural basis for the enhanced stability of highly fluorinated proteins

Structural basis for the recruitment of glycogen synthase by glycogenin

Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity

Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR

Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate

Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA

Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I

Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi

Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7

The Semaphorin Receptor Plexin-B1 Specifically Interacts with Active Rac in a Ligand-Dependent Manner

Physical Reasons for the Unusual α -Helix Stabilization Afforded by Charged or Neutral Polar Residues in Alanine-Rich Peptides

cDNA Cloning and Expression of the Human A-Type Platelet-Derived Growth Factor (PDGF) Receptor Establishes Structural Similarity to the B-Type PDGF Receptor

Expression of an Exogenous Eukaryotic DNA Methyltransferase Gene Induces Transformation of NIH 3T3 Cells

The gene for albicidin detoxification from Pantoea dispersa encodes an esterase and attenuates pathogenicity of Xanthomonas albilineans to sugarcane

Site-Directed Mutagenesis of Amino Acid Residues of Protein Phosphatase 1 Involved in Catalysis and Inhibitor Binding

B3(Fv)-PE38KDEL, A Single-Chain Immunotoxin that Causes Complete Regression of a Human Carcinoma in Mice

Dimerization and DNA Binding Alter Phosphorylation of Fos and Jun

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