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Cu-Catalyzed Couplings of Heteroaryl Primary Amines and (Hetero)aryl Bromides with 6‑Hydroxypicolinamide Ligands

Organic process research & development, 2019-08, Vol.23 (8), p.1538-1551

2019

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Recent Advances in Nonprecious Metal Catalysis

Organic process research & development, 2021-08, Vol.25 (8), p.1802-1815

2021

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Development of an Efficient Pd-Catalyzed Coupling Process for Axitinib

Organic process research & development, 2014-01, Vol.18 (1), p.266-274

2014

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A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor

Organic process research & development, 2017-06, Vol.21 (6), p.871-877

2017

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Streamlined Synthesis of the Bippyphos Family of Ligands and Cross-Coupling Applications

Organic process research & development, 2008-05, Vol.12 (3), p.480-489

2008

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Copper-Catalyzed Hydroxylation of Aryl Halides Using Hydroxypicolinamide Ligands

Organic process research & development, 2024-07, Vol.28 (7), p.2732-2742

2024

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Recent Advances in Nonprecious Metal Catalysis

Organic process research & development, 2023-11, Vol.27 (11), p.1913-1930

2023

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Recent Advances in Nonprecious Metal Catalysis

Organic process research & development, 2020-06, Vol.24 (6), p.909-915

2020

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Improvements to Enable the Large Scale Synthesis of 1‑{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833)

Organic process research & development, 2018-12, Vol.22 (12), p.1835-1845

2018

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Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19

Organic process research & development, 2023-02, Vol.27 (12), p.2223-2239

2023

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The Challenges of Developing an API Crystallization Process for a Complex Polymorphic and Highly Solvating System. Part I

Organic process research & development, 2009-11, Vol.13 (6), p.1327-1337

2009

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Recent Advances in Nonprecious Metal Catalysis

Organic process research & development, 2022-12, Vol.26 (12), p.3204-3215

2022

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pH-Dependent Degradation of T3P-Related Byproducts

Organic process research & development, 2021-03, Vol.25 (3), p.621-626

2021

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Ir-Catalyzed Borylation as an Efficient Route to a Nicotine Hapten

Organic process research & development, 2018-04, Vol.22 (4), p.527-534

2018

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Asymmetric Synthesis of the cis -1,2-Diaryltetralin Vepdegestrant Core via an Enantioselective Intramolecular Corey-Chaykovsky Epoxidation

Organic process research & development, 2024-11

2024

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Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β‑Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2H‑Pyranone

Organic process research & development, 2014-01, Vol.18 (1), p.26-35

2014

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Synthesis of Filibuvir. Part II. Second-Generation Synthesis of a 6,6-Disubstituted 2H‑Pyranone via Dieckmann Cyclization of a β‑Acetoxy Ester

Organic process research & development, 2014-01, Vol.18 (1), p.36-44

2014

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Practical Amination of Nitropyridones by Silylation

Organic process research & development, 2008-11, Vol.12 (6), p.1261-1264

2008

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Case Studies in the Development of Drug Substance Control Strategies

Organic process research & development, 2015-08, Vol.19 (8), p.935-948

2015

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Synthesis of a Bicyclic Piperazine from l-Aspartic Acid and Application of a Fluoride-Promoted SNAr Coupling

Organic process research & development, 2011-11, Vol.15 (6), p.1328-1335

2011

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Safe Execution of a Large-Scale Ozonolysis: Preparation of the Bisulfite Adduct of 2-Hydroxyindan-2-carboxaldehyde and Its Utility in a Reductive Amination

Organic process research & development, 2003-03, Vol.7 (2), p.155-160

2003

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Synthesis of a Bicyclic Piperazine from l -Aspartic Acid and Application of a Fluoride-Promoted S N Ar Coupling

Organic process research & development, 2011-11, Vol.15 (6), p.1328-1335

2011

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Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β-Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2 H -Pyranone

Organic process research & development, 2014-01, Vol.18 (1), p.26-35

2014

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Synthesis of Filibuvir. Part II. Second-Generation Synthesis of a 6,6-Disubstituted 2 H -Pyranone via Dieckmann Cyclization of a β-Acetoxy Ester

Organic process research & development, 2014-01, Vol.18 (1), p.36-44

2014

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Synthesis and Purification of 6-Ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic Acid Benzylamide

Organic process research & development, 2003-11, Vol.7 (6), p.873-878

2003

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Cu-Catalyzed Couplings of Heteroaryl Primary Amines and (Hetero)aryl Bromides with 6‑Hydroxypicolinamide Ligands

Recent Advances in Nonprecious Metal Catalysis

Development of an Efficient Pd-Catalyzed Coupling Process for Axitinib

A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor

Streamlined Synthesis of the Bippyphos Family of Ligands and Cross-Coupling Applications

Copper-Catalyzed Hydroxylation of Aryl Halides Using Hydroxypicolinamide Ligands

Recent Advances in Nonprecious Metal Catalysis

Recent Advances in Nonprecious Metal Catalysis

Improvements to Enable the Large Scale Synthesis of 1‑{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833)

Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19

The Challenges of Developing an API Crystallization Process for a Complex Polymorphic and Highly Solvating System. Part I

Recent Advances in Nonprecious Metal Catalysis

pH-Dependent Degradation of T3P-Related Byproducts

Ir-Catalyzed Borylation as an Efficient Route to a Nicotine Hapten

Asymmetric Synthesis of the cis -1,2-Diaryltetralin Vepdegestrant Core via an Enantioselective Intramolecular Corey-Chaykovsky Epoxidation

Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β‑Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2H‑Pyranone

Synthesis of Filibuvir. Part II. Second-Generation Synthesis of a 6,6-Disubstituted 2H‑Pyranone via Dieckmann Cyclization of a β‑Acetoxy Ester

Practical Amination of Nitropyridones by Silylation

Case Studies in the Development of Drug Substance Control Strategies

Synthesis of a Bicyclic Piperazine from l-Aspartic Acid and Application of a Fluoride-Promoted SNAr Coupling

Safe Execution of a Large-Scale Ozonolysis: Preparation of the Bisulfite Adduct of 2-Hydroxyindan-2-carboxaldehyde and Its Utility in a Reductive Amination

Synthesis of a Bicyclic Piperazine from l -Aspartic Acid and Application of a Fluoride-Promoted S N Ar Coupling

Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β-Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2 H -Pyranone

Synthesis of Filibuvir. Part II. Second-Generation Synthesis of a 6,6-Disubstituted 2 H -Pyranone via Dieckmann Cyclization of a β-Acetoxy Ester

Synthesis and Purification of 6-Ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic Acid Benzylamide

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