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Scaffolding Protein IQGAP1 Is Dispensable, but Its Overexpression Promotes Hepatocellular Carcinoma via YAP1 Signaling

Molecular and cellular biology, 2021-04, Vol.41 (4)

2021

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IQGAP1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling

Molecular and Cellular Biology, 2005-09, Vol.25 (18), p.7940-7952

2005

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IQGAP1 Regulates Endothelial Barrier Function via EB1-Cortactin Cross Talk

Molecular and cellular biology, 2014-09, Vol.34 (18), p.3546-3558

2014

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A Diacylglycerol-Protein Kinase C-RasGRP1 Pathway Directs Ras Activation upon Antigen Receptor Stimulation of T Cells

Molecular and Cellular Biology, 2005-06, Vol.25 (11), p.4426-4441

2005

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Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

Molecular and Cellular Biology, 2003-11, Vol.23 (21), p.7875-7886

2003

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Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site

Molecular and Cellular Biology, 2013-12, Vol.33 (24), p.4834-4843

2013

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Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent

Molecular and Cellular Biology, 2008-03, Vol.28 (5), p.1489-1502

2008

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Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Molecular and Cellular Biology, 2002-11, Vol.22 (22), p.7758-7768

2002

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Partial Cleavage of RasGAP by Caspases Is Required for Cell Survival in Mild Stress Conditions

Molecular and Cellular Biology, 2004-12, Vol.24 (23), p.10425-10436

2004

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Tryptophan Permease Gene TAT2 Confers High-Pressure Growth in Saccharomyces cerevisiae

Molecular and Cellular Biology, 2000-11, Vol.20 (21), p.8093-8102

2000

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Focal Adhesions Require Catalytic Activity of Src Family Kinases To Mediate Integrin-Matrix Adhesion

Molecular and Cellular Biology, 2002-02, Vol.22 (4), p.1203-1217

2002

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Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7965-7975

2004

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MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

Molecular and cellular biology, 2014-11, Vol.34 (22), p.4143-4164

2014

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Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA

Molecular and Cellular Biology, 2010-01, Vol.30 (2), p.508-523

2010

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RhoE Inhibits Cell Cycle Progression and Ras-Induced Transformation

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7829-7840

2004

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Downregulation of Rap1GAP Contributes to Ras Transformation

Molecular and Cellular Biology, 2007-10, Vol.27 (19), p.6647-6658

2007

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Suppression of Ras-Induced Apoptosis by the Rac GTPase

Molecular and Cellular Biology, 1999-09, Vol.19 (9), p.5892-5901

1999

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Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

Molecular and Cellular Biology, 1997-11, Vol.17 (11), p.6427-6436

1997

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Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

Molecular and Cellular Biology, 2001-11, Vol.21 (21), p.7429-7441

2001

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Extracellular Signal-Regulated Kinase 1 Interacts with and Phosphorylates CdGAP at an Important Regulatory Site

Molecular and Cellular Biology, 2005-08, Vol.25 (15), p.6314-6329

2005

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An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

Molecular and Cellular Biology, 1996-06, Vol.16 (6), p.3169-3178

1996

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Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

Molecular and Cellular Biology, 1992-05, Vol.12 (5), p.2050-2056

1992

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Regulation of the Small GTPase Rap1 and Extracellular Signal-Regulated Kinases by the Costimulatory Molecule CTLA-4

Molecular and Cellular Biology, 2005-05, Vol.25 (10), p.4117-4128

2005

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The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

Molecular and Cellular Biology, 1997-04, Vol.17 (4), p.2247-2256

1997

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Phosphotyrosine (p-Tyr)-Dependent and -Independent Mechanisms of p190 RhoGAP-p120 RasGAP Interaction: Tyr 1105 of p190, a Substrate for c-Src, Is the Sole p-Tyr Mediator of Complex Formation

Molecular and Cellular Biology, 1998-12, Vol.18 (12), p.7052-7063

1998

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Scaffolding Protein IQGAP1 Is Dispensable, but Its Overexpression Promotes Hepatocellular Carcinoma via YAP1 Signaling

IQGAP1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling

IQGAP1 Regulates Endothelial Barrier Function via EB1-Cortactin Cross Talk

A Diacylglycerol-Protein Kinase C-RasGRP1 Pathway Directs Ras Activation upon Antigen Receptor Stimulation of T Cells

Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site

Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent

Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Partial Cleavage of RasGAP by Caspases Is Required for Cell Survival in Mild Stress Conditions

Tryptophan Permease Gene TAT2 Confers High-Pressure Growth in Saccharomyces cerevisiae

Focal Adhesions Require Catalytic Activity of Src Family Kinases To Mediate Integrin-Matrix Adhesion

Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity

MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA

RhoE Inhibits Cell Cycle Progression and Ras-Induced Transformation

Downregulation of Rap1GAP Contributes to Ras Transformation

Suppression of Ras-Induced Apoptosis by the Rac GTPase

Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

Extracellular Signal-Regulated Kinase 1 Interacts with and Phosphorylates CdGAP at an Important Regulatory Site

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

Regulation of the Small GTPase Rap1 and Extracellular Signal-Regulated Kinases by the Costimulatory Molecule CTLA-4

The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

Phosphotyrosine (p-Tyr)-Dependent and -Independent Mechanisms of p190 RhoGAP-p120 RasGAP Interaction: Tyr 1105 of p190, a Substrate for c-Src, Is the Sole p-Tyr Mediator of Complex Formation

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