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Importance of tumor affinity of nitroazoles in hypoxic radiosensitization

International journal of radiation oncology, biology, physics, 1989-04, Vol.16 (4), p.1033-1037

1989

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The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: Evidence for therapeutic gain

International journal of radiation oncology, biology, physics, 1987-04, Vol.13 (4), p.579-585

1987

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The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay

International journal of radiation oncology, biology, physics, 1989-04, Vol.16 (4), p.973-976

1989

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The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962–1984

International journal of radiation oncology, biology, physics, 1985, Vol.11 (1), p.5-22

1985

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Palliation of advanced pelvic malignant disease with large fraction pelvic radiation and misonidazole: Final report of rtog phase I/II study

International journal of radiation oncology, biology, physics, 1987-10, Vol.13 (10), p.1479-1482

1987

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Failure of misonidazole-sensitized radiotherapy to impact upon outcome among stage III–IV squamous cancers of the head and neck

International journal of radiation oncology, biology, physics, 1987-08, Vol.13 (8), p.1155-1160

1987

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Modification of chemotherapy by nitroimidazoles

International journal of radiation oncology, biology, physics, 1984-09, Vol.10 (9), p.1585-1594

Siemann, Dietmar W

1984

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Keynote address: Cellular reduction of nitroimidazole drugs: Potential for selective chemotherapy and diagnosis of hypoxic cells

International Journal of Radiation Oncology, Biology, & Physics [INT. J. RADIAT. ONCOL. BIOL. PHYS.]. Vol. 16, no. 4. 1989, 1989-04, Vol.16 (4), p.911-917

1989

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Sensitizers and radiation dose fractionation: Results and interpretations

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1049-1054

Hill, R.P.

1986

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The clinical testing of Ro 03-8799—Pharmacokinetics, toxicology, tissue and tumor concentrations

International journal of radiation oncology, biology, physics, 1984-09, Vol.10 (9), p.1759-1763

1984

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Pharmacology and toxicology of sensitizers: Mechanism studies

International journal of radiation oncology, biology, physics, 1984-08, Vol.10 (8), p.1293-1300

Rauth, A.M.

1984

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Clinical trials of radiosensitizers: What should we expect?

International journal of radiation oncology, biology, physics, 1984-03, Vol.10 (3), p.425-429

Brown, J.Martin

1984

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Misonidazole combined with hyperfractionation in the management of malignant glioma

International journal of radiation oncology, biology, physics, 1984-09, Vol.10 (9), p.1709-1712

1984

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The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles

International journal of radiation oncology, biology, physics, 1982-03, Vol.8 (3), p.675-682

Brown, J.Martin

1982

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Hypoxic cell radiosensitizers: Expectations and progress in drug development

International journal of radiation oncology, biology, physics, 1985-02, Vol.11 (2), p.323-329

Norman Coleman, C.

1985

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Analogues of RSU-1069: Radiosensitization and toxicity in vitro and in vivo

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1079-1081

1986

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A new ruthenium radiosensitizer: RuCl2(DMSO)2(4-nitroimidazole)2

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1059

1986

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The radiosensitizing and toxic effects of RSU-1069 on hypoxic cells in a murine tumor

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1091-1095

1986

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Radiosensitization in vitro and in vivo by 3-nitrotriazoles

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1063-1066

1986

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Leg contracture in mice: an assay of normal tissue response

International journal of radiation oncology, biology, physics, 1984-07, Vol.10 (7), p.1053-1061

Stone, Helen B.

1984

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Variation in sensitizing efficiency for SR 2508 in human cells dependent on glutathione content

International journal of radiation oncology, biology, physics, 1986-09, Vol.12 (9), p.1627-1635

1986

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Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508

International journal of radiation oncology, biology, physics, 1984-08, Vol.10 (8), p.1265-1269

1984

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Autoradiographic study of tritium-labeled misonidazole in the mouse

International journal of radiation oncology, biology, physics, 1989-04, Vol.16 (4), p.953-956

1989

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Changes in misonidazole binding with hypoxic fraction in mouse tumors

International journal of radiation oncology, biology, physics, 1985-07, Vol.11 (7), p.1349-1355

1985

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Studies on the toxicity of RSU-1069

International journal of radiation oncology, biology, physics, 1986-07, Vol.12 (7), p.1219-1222

1986

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Importance of tumor affinity of nitroazoles in hypoxic radiosensitization

The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: Evidence for therapeutic gain

The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay

The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962–1984

Palliation of advanced pelvic malignant disease with large fraction pelvic radiation and misonidazole: Final report of rtog phase I/II study

Failure of misonidazole-sensitized radiotherapy to impact upon outcome among stage III–IV squamous cancers of the head and neck

Modification of chemotherapy by nitroimidazoles

Keynote address: Cellular reduction of nitroimidazole drugs: Potential for selective chemotherapy and diagnosis of hypoxic cells

Sensitizers and radiation dose fractionation: Results and interpretations

The clinical testing of Ro 03-8799—Pharmacokinetics, toxicology, tissue and tumor concentrations

Pharmacology and toxicology of sensitizers: Mechanism studies

Clinical trials of radiosensitizers: What should we expect?

Misonidazole combined with hyperfractionation in the management of malignant glioma

The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles

Hypoxic cell radiosensitizers: Expectations and progress in drug development

Analogues of RSU-1069: Radiosensitization and toxicity in vitro and in vivo

A new ruthenium radiosensitizer: RuCl2(DMSO)2(4-nitroimidazole)2

The radiosensitizing and toxic effects of RSU-1069 on hypoxic cells in a murine tumor

Radiosensitization in vitro and in vivo by 3-nitrotriazoles

Leg contracture in mice: an assay of normal tissue response

Variation in sensitizing efficiency for SR 2508 in human cells dependent on glutathione content

Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508

Autoradiographic study of tritium-labeled misonidazole in the mouse

Changes in misonidazole binding with hypoxic fraction in mouse tumors

Studies on the toxicity of RSU-1069

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