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Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (2), p.776-784

2013

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Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (3), p.375-376

Cole, Kristina A

2020

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CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15), p.3155-3166

2015

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Common Variation at BARD1 Results in the Expression of an Oncogenic Isoform That Influences Neuroblastoma Susceptibility and Oncogenicity

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8), p.2068-2078

2012

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Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Cancer research (Chicago, Ill.), 2013-11, Vol.73 (22), p.6757-6769

2013

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Abstract CT029: Pediatric phase 2 trial of the WEE1 inhibitor adavosertib (AZD1775) and irinotecan: A Children's Oncology Group Study (ADVL1312)

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.CT029-CT029

2021

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Abstract CT144: Pediatric phase I trial of the WEE1 inhibitor AZD1775 and irinotecan in patients with refractory solid and CNS malignancies; A Children’s Oncology Group Study (ADVL1312)

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.CT144-CT144

2017

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Abstract 4305: NMI as a biomarker of response to CDK4/6 inhibition in a preclinical model of neuroblastoma

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4305-4305

2015

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Abstract A2-09: Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations

Cancer research (Chicago, Ill.), 2015-11, Vol.75 (22_Supplement_1), p.A2-A2-09

2015

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Abstract PR10: Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations

Cancer research (Chicago, Ill.), 2015-11, Vol.75 (22_Supplement_2), p.PR10-PR10

2015

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Abstract 6372: Germline pathogenic variants are enriched in pediatric central nervous system tumor patients and associate with somatic functional consequences

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6372-6372

2024

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Abstract 4758: Inhibition of checkpoint kinase 1 (Chk1) as a potential therapeutic for pediatric neuroblastoma

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4758-4758

2011

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Abstract 1436: Therapeutic targeting of the DNA damage mediators CHK1 and Wee1 in neuroblastoma

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1436-1436

2012

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COMBINATION THERAPY TARGETING THE CHK1 AND WEE1 KINASES DEMONSTRATES THERAPEUTIC EFFICACY IN NEUROBLASTOMA

Cancer research (Chicago, Ill.), 2012-11, Vol.73 (2), p.776-784

2012

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Abstract 4871: New neuroblastoma susceptibility loci at 6q21 within HACE1 and LIN28B

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4871-4871

2012

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Abstract 5263: An RNAi screen of the protein kinome identifies CHEK1 as a therapeutic target in neuroblastoma

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5263-5263

2010

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Lack of p53 Augments Antitumor Functions in Cytolytic T Cells

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (18), p.5229-5240

2016

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Abstract 5237: The long intergenic noncoding RNA LINC00340 is a neuroblastoma susceptibility gene

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5237-5237

2014

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Abstract 144: CASC15 is a tumor suppressor lncRNA at the 6p22 neuroblastoma susceptibility locus

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.144-144

2015

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Lack of p53 Augments Anti-Tumor Functions in Cytolytic T Cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (18), p.5229-5240

2016

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Abstract LB-475: 3′UTR polymorphisms affect expression and activity of IGF1R, a therapeutic target in pediatric neuroblastoma

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.LB-475-LB-475

2012

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Abstract 5566: Elevated CXCR4 expression is clinically correlated with advanced stage neuroblastoma: examination of its role as a possible therapeutic target

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5566-5566

2012

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Abstract 2744: CDK4/CDK6 inhibition is potently active in a definable subset of human neuroblastomas

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2744-2744

2013

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Abstract 3867: Understanding the neuroblastoma predisposition signal at chromosome 2q35: Identification of the β-BARD1 isoform as an oncogenic driver

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.3867-3867

2010

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Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers

Cancer research (Chicago, Ill.), 1996-02, Vol.56 (3), p.569-573

1996

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Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma

Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus

Common Variation at BARD1 Results in the Expression of an Oncogenic Isoform That Influences Neuroblastoma Susceptibility and Oncogenicity

Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Abstract CT029: Pediatric phase 2 trial of the WEE1 inhibitor adavosertib (AZD1775) and irinotecan: A Children's Oncology Group Study (ADVL1312)

Abstract CT144: Pediatric phase I trial of the WEE1 inhibitor AZD1775 and irinotecan in patients with refractory solid and CNS malignancies; A Children’s Oncology Group Study (ADVL1312)

Abstract 4305: NMI as a biomarker of response to CDK4/6 inhibition in a preclinical model of neuroblastoma

Abstract A2-09: Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations

Abstract PR10: Oncogenic dysregulations in neuroblastoma are associated with distal large chromosomal aberrations

Abstract 6372: Germline pathogenic variants are enriched in pediatric central nervous system tumor patients and associate with somatic functional consequences

Abstract 4758: Inhibition of checkpoint kinase 1 (Chk1) as a potential therapeutic for pediatric neuroblastoma

Abstract 1436: Therapeutic targeting of the DNA damage mediators CHK1 and Wee1 in neuroblastoma

COMBINATION THERAPY TARGETING THE CHK1 AND WEE1 KINASES DEMONSTRATES THERAPEUTIC EFFICACY IN NEUROBLASTOMA

Abstract 4871: New neuroblastoma susceptibility loci at 6q21 within HACE1 and LIN28B

Abstract 5263: An RNAi screen of the protein kinome identifies CHEK1 as a therapeutic target in neuroblastoma

Lack of p53 Augments Antitumor Functions in Cytolytic T Cells

Abstract 5237: The long intergenic noncoding RNA LINC00340 is a neuroblastoma susceptibility gene

Abstract 144: CASC15 is a tumor suppressor lncRNA at the 6p22 neuroblastoma susceptibility locus

Lack of p53 Augments Anti-Tumor Functions in Cytolytic T Cells

Abstract LB-475: 3′UTR polymorphisms affect expression and activity of IGF1R, a therapeutic target in pediatric neuroblastoma

Abstract 5566: Elevated CXCR4 expression is clinically correlated with advanced stage neuroblastoma: examination of its role as a possible therapeutic target

Abstract 2744: CDK4/CDK6 inhibition is potently active in a definable subset of human neuroblastomas

Abstract 3867: Understanding the neuroblastoma predisposition signal at chromosome 2q35: Identification of the β-BARD1 isoform as an oncogenic driver

Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers

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