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Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D

Cancer research (Chicago, Ill.), 2006-03, Vol.66 (6), p.3177-3187

2006

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Abstract 5340: Novel small-molecule antagonists of the PD1/PD-L1 axis

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5340-5340

2020

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Lamellarin D: A novel potent inhibitor of topoisomerase I

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (21), p.7392-7399

2003

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Abstract 2428: Translational study of F14512, a novel vectorised epipodophyllotoxin, which demonstrates a marked activity on ovarian cancer models from patients

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2428-2428

2015

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F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (23), p.9845-9853

2008

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Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506

Cancer research (Chicago, Ill.), 2001-09, Vol.61 (18), p.6876-6884

2001

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Abstract 1219: Patient-derived tumor models of resistant metastatic melanoma

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1219-1219

2014

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Abstract 3799: Polyamine Transport System (PTS) activity and hijacking in cancer cells: New option in Head and Neck tumors treatment with the polyamine-containing drug candidate F14512

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3799-3799

2012

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Abstract 5565: Tumor targeting and enhanced efficacy of novel polyamine-cytotoxic conjugates

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.5565-5565

2013

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Abstract 4580: A novel role for Junctional Adhesion Molecule-A (JAM-A) in tumor proliferation: modulation by a humanized anti-JAM-A monoclonal antibody

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4580-4580

2011

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Abstract 988: F14512, a novel vectorized topoiserase II inhibitor, bypasses MDR1 mediated resistance

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.988-988

2013

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Abstract 1925: Trifluoromethylated artemisinin dimers demonstrate a potent anti-cancer activity in vitro and in vivo

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1925-1925

2012

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Abstract 4571: 515H7, a novel anti-CXCR4 antibody: In vitro efficacy on CXCR4-associated signaling pathways and in vivo anti-tumor activity

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4571-4571

2011

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Abstract 2448: h224G11, a humanized whole antibody targeting the c-Met receptor, induces c-Met down-regulation and triggers ADCC functions

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2448-2448

2010

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Distribution of furamidine analogues in tumor cells: Targeting of the nucleus or mitochondria depending on the amidine substitution

Cancer research (Chicago, Ill.), 2002-12, Vol.62 (24), p.7219-7229

2002

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Abstract 3518: In vitro and in vivo synergistic effects of F14512, a novel targeted cytotoxic agent in phase I clinical study, in combination with other anticancer drugs

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3518-3518

2011

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Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma models

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3261-3261

2011

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Abstract 2747: Synergistic antileukemic activity of F14512 in combination with AraC

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2747-2747

2012

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Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties

Cancer research (Chicago, Ill.), 1999-06, Vol.59 (12), p.2939-2943

1999

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Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103

Cancer research (Chicago, Ill.), 2000-08, Vol.60 (15), p.4077-4084

2000

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Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site

Cancer research (Chicago, Ill.), 2001-01, Vol.61 (2), p.504-508

2001

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Abstract 5461: Novel antitumor amino-pancratistatin derivatives inhibitors of protein and DNA synthesis

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5461-5461

2010

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Intercalation into DNA is not required for inhibition of topoisomerase I by indolocarbazole antitumor agents

Cancer research (Chicago, Ill.), 1999-06, Vol.59 (12), p.2853-2860

1999

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Poisoning of topoisomerase I by an antitumor indolocarbazole drug : Stabilization of topoisomerase I-DNA covalent complexes and specific inhibition of the protein kinase activity

Cancer research (Chicago, Ill.), 1999, Vol.59 (1), p.52-55

1999

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Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D

Abstract 5340: Novel small-molecule antagonists of the PD1/PD-L1 axis

Lamellarin D: A novel potent inhibitor of topoisomerase I

Abstract 2428: Translational study of F14512, a novel vectorised epipodophyllotoxin, which demonstrates a marked activity on ovarian cancer models from patients

F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system

Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506

Abstract 1219: Patient-derived tumor models of resistant metastatic melanoma

Abstract 3799: Polyamine Transport System (PTS) activity and hijacking in cancer cells: New option in Head and Neck tumors treatment with the polyamine-containing drug candidate F14512

Abstract 5565: Tumor targeting and enhanced efficacy of novel polyamine-cytotoxic conjugates

Abstract 4580: A novel role for Junctional Adhesion Molecule-A (JAM-A) in tumor proliferation: modulation by a humanized anti-JAM-A monoclonal antibody

Abstract 988: F14512, a novel vectorized topoiserase II inhibitor, bypasses MDR1 mediated resistance

Abstract 1925: Trifluoromethylated artemisinin dimers demonstrate a potent anti-cancer activity in vitro and in vivo

Abstract 4571: 515H7, a novel anti-CXCR4 antibody: In vitro efficacy on CXCR4-associated signaling pathways and in vivo anti-tumor activity

Abstract 2448: h224G11, a humanized whole antibody targeting the c-Met receptor, induces c-Met down-regulation and triggers ADCC functions

Distribution of furamidine analogues in tumor cells: Targeting of the nucleus or mitochondria depending on the amidine substitution

Abstract 3518: In vitro and in vivo synergistic effects of F14512, a novel targeted cytotoxic agent in phase I clinical study, in combination with other anticancer drugs

Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma models

Abstract 2747: Synergistic antileukemic activity of F14512 in combination with AraC

Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties

Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103

Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site

Abstract 5461: Novel antitumor amino-pancratistatin derivatives inhibitors of protein and DNA synthesis

Intercalation into DNA is not required for inhibition of topoisomerase I by indolocarbazole antitumor agents

Poisoning of topoisomerase I by an antitumor indolocarbazole drug : Stabilization of topoisomerase I-DNA covalent complexes and specific inhibition of the protein kinase activity

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