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Populations of in silico myocytes and tissues reveal synergy of multiatrial‐predominant K+‐current block in atrial fibrillation

British journal of pharmacology, 2020-10, Vol.177 (19), p.4497-4515

2020

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Modulation of K2P2.1 and K2P10.1 K+ channel sensitivity to carvedilol by alternative mRNA translation initiation

British journal of pharmacology, 2014-12, Vol.171 (23), p.5182-5194

2014

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Anti‐arrhythmic investigations in large animal models of atrial fibrillation

British journal of pharmacology, 2022-03, Vol.179 (5), p.838-858

2022

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OCT2013, an ischaemia‐activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine

British journal of pharmacology, 2022-05, Vol.179 (9), p.2037-2053

2022

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The antiarrhythmic compound efsevin directly modulates voltage‐dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake

British journal of pharmacology, 2020-07, Vol.177 (13), p.2947-2958

2020

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LUF7244, an allosteric modulator/activator of Kv11.1 channels, counteracts dofetilide‐induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model

British journal of pharmacology, 2019-10, Vol.176 (19), p.3871-3885

2019

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A carvedilol analogue, VK‐II‐86, prevents hypokalaemia‐induced ventricular arrhythmia through novel multi‐channel effects

British journal of pharmacology, 2022-06, Vol.179 (11), p.2713-2732

2022

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Facilitation of ischaemia‐induced ventricular fibrillation by catecholamines is mediated by β1 and β2 agonism in the rat heart in vitro

British journal of pharmacology, 2018-05, Vol.175 (10), p.1669-1690

2018

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The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43

British journal of pharmacology, 2006-03, Vol.147 (5), p.486-495

2006

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The transient receptor potential melastatin 4 channel inhibitor 9‐phenanthrol modulates cardiac sodium channel

British journal of pharmacology, 2018-12, Vol.175 (23), p.4325-4337

2018

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The ‘overly‐sensitive’ heart: sodium channel block and QRS interval prolongation

British journal of pharmacology, 2011-09, Vol.164 (2), p.254-259

2011

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Feasibility of targeting ischaemia‐related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids

British journal of pharmacology, 2013-08, Vol.169 (8), p.1840-1848

2013

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Phase 2 ventricular arrhythmias in acute myocardial infarction: a neglected target for therapeutic antiarrhythmic drug development and for safety pharmacology evaluation

British journal of pharmacology, 2005-07, Vol.145 (5), p.551-564

2005

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Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine

British journal of pharmacology, 2002-07, Vol.136 (5), p.717-729

2002

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n‐3 (omega‐3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling

British journal of pharmacology, 2007-02, Vol.150 (3), p.281-285

2007

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Self‐augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency

British journal of pharmacology, 2009-04, Vol.156 (7), p.1076-1084

2009

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Carvedilol targets human K2P3.1 (TASK1) K+ leak channels

British journal of pharmacology, 2011-07, Vol.163 (5), p.1099-1110

2011

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Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes

British journal of pharmacology, 2008-03, Vol.153 (5), p.915-925

2008

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Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone

British journal of pharmacology, 2001-07, Vol.133 (5), p.625-634

2001

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Peroxynitrite: in vivo cardioprotectant or arrhythmogen?

British journal of pharmacology, 2008-12, Vol.155 (7), p.972-973

2008

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Nitric oxide fails to confer endogenous antiarrhythmic cardioprotection in the primate heart in vitro

British journal of pharmacology, 2007-04, Vol.150 (7), p.893-898

2007

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Molecular impact of MinK on the enantiospecific block of IKs by chromanols

British journal of pharmacology, 2000-12, Vol.131 (8), p.1503-1506

2000

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Ranolazine and late cardiac sodium current – a therapeutic target for angina, arrhythmia and more?

British journal of pharmacology, 2006-05, Vol.148 (1), p.4-6

2006

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Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels

British journal of pharmacology, 2003-11, Vol.140 (5), p.996-1002

2003

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Bepridil differentially inhibits two delayed rectifier K(+) currents, I(Kr) and I(Ks), in guinea-pig ventricular myocytes

British journal of pharmacology, 1999-12, Vol.128 (8), p.1733-1738

1999

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Populations of in silico myocytes and tissues reveal synergy of multiatrial‐predominant K+‐current block in atrial fibrillation

Modulation of K2P2.1 and K2P10.1 K+ channel sensitivity to carvedilol by alternative mRNA translation initiation

Anti‐arrhythmic investigations in large animal models of atrial fibrillation

OCT2013, an ischaemia‐activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine

The antiarrhythmic compound efsevin directly modulates voltage‐dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake

LUF7244, an allosteric modulator/activator of Kv11.1 channels, counteracts dofetilide‐induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model

A carvedilol analogue, VK‐II‐86, prevents hypokalaemia‐induced ventricular arrhythmia through novel multi‐channel effects

Facilitation of ischaemia‐induced ventricular fibrillation by catecholamines is mediated by β1 and β2 agonism in the rat heart in vitro

The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43

The transient receptor potential melastatin 4 channel inhibitor 9‐phenanthrol modulates cardiac sodium channel

The ‘overly‐sensitive’ heart: sodium channel block and QRS interval prolongation

Feasibility of targeting ischaemia‐related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids

Phase 2 ventricular arrhythmias in acute myocardial infarction: a neglected target for therapeutic antiarrhythmic drug development and for safety pharmacology evaluation

Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine

n‐3 (omega‐3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling

Self‐augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency

Carvedilol targets human K2P3.1 (TASK1) K+ leak channels

Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes

Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone

Peroxynitrite: in vivo cardioprotectant or arrhythmogen?

Nitric oxide fails to confer endogenous antiarrhythmic cardioprotection in the primate heart in vitro

Molecular impact of MinK on the enantiospecific block of IKs by chromanols

Ranolazine and late cardiac sodium current – a therapeutic target for angina, arrhythmia and more?

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels

Bepridil differentially inhibits two delayed rectifier K(+) currents, I(Kr) and I(Ks), in guinea-pig ventricular myocytes

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