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Emerging therapies for inv(16) AML

Blood, 2021-05, Vol.137 (19), p.2579-2584

2021

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In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

Blood, 2013-02, Vol.121 (8), p.1255-1264

2013

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C/EBPβ is required for survival of Ly6C− monocytes

Blood, 2017-10, Vol.130 (16), p.1809-1818

2017

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Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

Blood, 2010-03, Vol.115 (9), p.1768-1778

2010

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β-Catenin–TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation

Blood, 2020-11, Vol.136 (22), p.2574-2587

2020

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Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Blood, 2023-06, Vol.141 (25), p.3078-3090

2023

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LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

Blood, 2018-04, Vol.131 (15), p.1730-1742

2018

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IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

Blood, 2009-07, Vol.114 (2), p.346-356

2009

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Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice

Blood, 2017-04, Vol.129 (14), p.1901-1912

2017

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Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

Blood, 2011-07, Vol.118 (4), p.965-974

2011

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Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Blood, 2020-10, Vol.136 (15), p.1735-1747

2020

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The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

Blood, 2019-07, Vol.134 (3), p.239-251

2019

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Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial

Blood, 2007-01, Vol.109 (2), p.492-496

2007

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Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells

Blood, 2015-08, Vol.126 (9), p.1086-1094

2015

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Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

Blood, 2009-12, Vol.114 (27), p.5415-5425

2009

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Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Blood, 2011-03, Vol.117 (10), p.2827-2838

2011

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Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Blood, 2009-07, Vol.114 (2), p.299-309

2009

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Runx1 exon 6–related alternative splicing isoforms differentially regulate hematopoiesis in mice

Blood, 2014-06, Vol.123 (24), p.3760-3769

2014

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The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

Blood, 2014-10, Vol.124 (15), p.2391-2399

2014

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Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

Blood, 2013-02, Vol.121 (8), p.1413-1421

2013

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The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Blood, 2011-12, Vol.118 (25), p.6544-6552

2011

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Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1

Blood, 2011-09, Vol.118 (11), p.3096-3106

2011

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Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells

Blood, 2009-12, Vol.114 (24), p.5024-5033

2009

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Emerging therapies for inv(16) AML

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

C/EBPβ is required for survival of Ly6C− monocytes

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

β-Catenin–TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice

Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial

Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Runx1 exon 6–related alternative splicing isoforms differentially regulate hematopoiesis in mice

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1

Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells

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