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Backstepping Mechanism of Kinesin-1

Biophysical journal, 2020-11, Vol.119 (10), p.1984-1994

2020

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Modulation of Kinesin’s Load-Bearing Capacity by Force Geometry and the Microtubule Track

Biophysical journal, 2020-01, Vol.118 (1), p.243-253

2020

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Acetylated Microtubules Are Preferentially Bundled Leading to Enhanced Kinesin-1 Motility

Biophysical journal, 2017-10, Vol.113 (7), p.1551-1560

2017

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Speed and Diffusion of Kinesin-2 Are Competing Limiting Factors in Flagellar Length-Control Model

Biophysical journal, 2020-06, Vol.118 (11), p.2790-2800

2020

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Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for In Vivo Function

Biophysical journal, 2014-10, Vol.107 (8), p.1896-1904

2014

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Hitching a Ride: Mechanics of Transport Initiation through Linker-Mediated Hitchhiking

Biophysical journal, 2020-03, Vol.118 (6), p.1357-1369

2020

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The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

Biophysical journal, 2016-03, Vol.110 (6), p.1216-1225

Hancock, William O.

2016

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Single-Nanoparticle Tracking with Angstrom Localization Precision and Microsecond Time Resolution

Biophysical journal, 2018-12, Vol.115 (12), p.2413-2427

2018

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Three-Dimensional Optical Tweezers Tracking Resolves Random Sideward Steps of the Kinesin-8 Kip3

Biophysical journal, 2018-11, Vol.115 (10), p.1993-2002

2018

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Modeling the motion of disease-associated KIF1A heterodimers

Biophysical journal, 2023-11, Vol.122 (22), p.4348-4359

2023

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Kinesin-5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck-Linker Binding Sites

Biophysical journal, 2014-11, Vol.107 (9), p.2204-2213

2014

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A Unified Walking Model for Dimeric Motor Proteins

Biophysical journal, 2018-11, Vol.115 (10), p.1981-1992

2018

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Tracking Single Particles and Elongated Filaments with Nanometer Precision

Biophysical journal, 2011-06, Vol.100 (11), p.2820-2828

2011

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Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?

Biophysical journal, 2014-09, Vol.107 (6), p.1474-1484

2014

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Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

Biophysical journal, 2014-06, Vol.106 (12), p.2636-2643

2014

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Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Biophysical journal, 2023-04, Vol.122 (7), p.1168-1184

2023

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Spontaneous Formation of a Globally Connected Contractile Network in a Microtubule-Motor System

Biophysical journal, 2016-07, Vol.111 (2), p.373-385

2016

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Simulations suggest robust microtubule attachment of kinesin and dynein in antagonistic pairs

Biophysical journal, 2023-08, Vol.122 (16), p.3299-3313

2023

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Two Kinesins Transport Cargo Primarily via the Action of One Motor: Implications for Intracellular Transport

Biophysical journal, 2010-11, Vol.99 (9), p.2967-2977

2010

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Mapping the Processivity Determinants of the Kinesin-3 Motor Domain

Biophysical journal, 2015-10, Vol.109 (8), p.1537-1540

2015

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Phragmoplast Orienting Kinesin 2 Is a Weak Motor Switching between Processive and Diffusive Modes

Biophysical journal, 2018-07, Vol.115 (2), p.375-385

2018

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Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

Biophysical journal, 2014-04, Vol.106 (8), p.1691-1700

2014

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Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State

Biophysical journal, 2017-06, Vol.112 (12), p.2615-2623

2017

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Challenges in Estimating the Motility Parameters of Single Processive Motor Proteins

Biophysical journal, 2017-12, Vol.113 (11), p.2433-2443

2017

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Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors

Biophysical journal, 2019-03, Vol.116 (6), p.1115-1126

2019

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Backstepping Mechanism of Kinesin-1

Modulation of Kinesin’s Load-Bearing Capacity by Force Geometry and the Microtubule Track

Acetylated Microtubules Are Preferentially Bundled Leading to Enhanced Kinesin-1 Motility

Speed and Diffusion of Kinesin-2 Are Competing Limiting Factors in Flagellar Length-Control Model

Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for In Vivo Function

Hitching a Ride: Mechanics of Transport Initiation through Linker-Mediated Hitchhiking

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

Single-Nanoparticle Tracking with Angstrom Localization Precision and Microsecond Time Resolution

Three-Dimensional Optical Tweezers Tracking Resolves Random Sideward Steps of the Kinesin-8 Kip3

Modeling the motion of disease-associated KIF1A heterodimers

Kinesin-5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck-Linker Binding Sites

A Unified Walking Model for Dimeric Motor Proteins

Tracking Single Particles and Elongated Filaments with Nanometer Precision

Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?

Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Spontaneous Formation of a Globally Connected Contractile Network in a Microtubule-Motor System

Simulations suggest robust microtubule attachment of kinesin and dynein in antagonistic pairs

Two Kinesins Transport Cargo Primarily via the Action of One Motor: Implications for Intracellular Transport

Mapping the Processivity Determinants of the Kinesin-3 Motor Domain

Phragmoplast Orienting Kinesin 2 Is a Weak Motor Switching between Processive and Diffusive Modes

Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State

Challenges in Estimating the Motility Parameters of Single Processive Motor Proteins

Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors

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