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QM/MM Study of the Catalytic Mechanism and Substrate Specificity of the Aromatic Substrate C‑Methyltransferase Fur6

Biochemistry (Easton), 2024-03, Vol.63 (6), p.806-814

2024

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Association of Increased Homocysteine Levels with Impaired Folate Metabolism and Vitamin B Deficiency in Early-Onset Multiple Sclerosis

Biochemistry (Moscow), 2024-03, Vol.89 (3), p.562-573

2024

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The Functions of N 6 -Methyladenosine in Nuclear RNAs

Biochemistry (Moscow), 2024-01, Vol.89 (1), p.159

2024

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Rare Catechol‑O‑methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Biochemistry (Easton), 2023-04, Vol.62 (8), p.1394-1405

2023

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Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin

Biochemistry (Easton), 2023-02, Vol.62 (3), p.695-699

2023

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Elucidating the Kinetic Mechanism of Human METTL16

Biochemistry (Easton), 2023-01, Vol.62 (2), p.494-506

2023

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Arginine Methylation of the PGC-1α C‑Terminus Is Temperature-Dependent

Biochemistry (Easton), 2023-01, Vol.62 (1), p.22-34

2023

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Human Protein‑l‑isoaspartate O‑Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins

Biochemistry (Easton), 2022-05, Vol.61 (10), p.879-894

2022

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Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N‑Methyltransferases in Bacteria

Biochemistry (Easton), 2022-02, Vol.61 (3), p.183-194

2022

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Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes

Biochemistry (Easton), 2022-01, Vol.61 (1), p.1-9

2022

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Overall Retention of Methyl Stereochemistry during B 12 -Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis

Biochemistry (Easton), 2021-05, Vol.60 (20), p.1587-1596

2021

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HutW from Vibrio cholerae Is an Anaerobic Heme-Degrading Enzyme with Unique Functional Properties

Biochemistry (Easton), 2021-03, Vol.60 (9), p.699-710

2021

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Characterization of the Kinetic Mechanism of Human Protein Arginine Methyltransferase 5

Biochemistry (Easton), 2020-12, Vol.59 (50), p.4775-4786

2020

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Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences

Biochemistry (Easton), 2020-07, Vol.59 (27), p.2541-2550

2020

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RNA (C5-cytosine) Methyltransferases

Biochemistry (Moscow), 2019-08, Vol.84 (8), p.851-869

2019

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Structural and Functional Characterization of Sulfonium Carbon–Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1

Biochemistry (Easton), 2019-04, Vol.58 (16), p.2152-2159

2019

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The Crg1 N‑Terminus Is Essential for Methyltransferase Activity and Cantharidin Resistance in Saccharomyces cerevisiae

Biochemistry (Easton), 2019-04, Vol.58 (13), p.1799-1809

2019

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A Family Divided: Distinct Structural and Mechanistic Features of the SpoU-TrmD (SPOUT) Methyltransferase Superfamily

Biochemistry (Easton), 2019-02, Vol.58 (5), p.336-345

2019

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Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding

Biochemistry (Easton), 2019-02, Vol.58 (5), p.346-354

2019

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The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains

Biochemistry (Easton), 2018-12, Vol.57 (50), p.6827-6837

2018

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Maintenance DNA Methyltransferase Activity in the Presence of Oxidized Forms of 5‑Methylcytosine: Structural Basis for Ten Eleven Translocation-Mediated DNA Demethylation

Biochemistry (Easton), 2018-10, Vol.57 (42), p.6061-6069

2018

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Nicotinamide N‑Methyltransferase Interacts with Enzymes of the Methionine Cycle and Regulates Methyl Donor Metabolism

Biochemistry (Easton), 2018-10, Vol.57 (40), p.5775-5779

2018

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Mycofactocin Biosynthesis Proceeds through 3‑Amino-5-[(p‑hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity toward MftA

Biochemistry (Easton), 2018-09, Vol.57 (37), p.5379-5383

2018

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Investigation of Solvent Hydron Exchange in the Reaction Catalyzed by the Antibiotic Resistance Protein Cfr

Biochemistry (Easton), 2018-07, Vol.57 (30), p.4431-4439

2018

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Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface

Biochemistry (Easton), 2018-07, Vol.57 (29), p.4312-4324

2018

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QM/MM Study of the Catalytic Mechanism and Substrate Specificity of the Aromatic Substrate C‑Methyltransferase Fur6

Association of Increased Homocysteine Levels with Impaired Folate Metabolism and Vitamin B Deficiency in Early-Onset Multiple Sclerosis

The Functions of N 6 -Methyladenosine in Nuclear RNAs

Rare Catechol‑O‑methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin

Elucidating the Kinetic Mechanism of Human METTL16

Arginine Methylation of the PGC-1α C‑Terminus Is Temperature-Dependent

Human Protein‑l‑isoaspartate O‑Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins

Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N‑Methyltransferases in Bacteria

Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes

Overall Retention of Methyl Stereochemistry during B 12 -Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis

HutW from Vibrio cholerae Is an Anaerobic Heme-Degrading Enzyme with Unique Functional Properties

Characterization of the Kinetic Mechanism of Human Protein Arginine Methyltransferase 5

Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences

RNA (C5-cytosine) Methyltransferases

Structural and Functional Characterization of Sulfonium Carbon–Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1

The Crg1 N‑Terminus Is Essential for Methyltransferase Activity and Cantharidin Resistance in Saccharomyces cerevisiae

A Family Divided: Distinct Structural and Mechanistic Features of the SpoU-TrmD (SPOUT) Methyltransferase Superfamily

Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding

The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains

Maintenance DNA Methyltransferase Activity in the Presence of Oxidized Forms of 5‑Methylcytosine: Structural Basis for Ten Eleven Translocation-Mediated DNA Demethylation

Nicotinamide N‑Methyltransferase Interacts with Enzymes of the Methionine Cycle and Regulates Methyl Donor Metabolism

Mycofactocin Biosynthesis Proceeds through 3‑Amino-5-[(p‑hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity toward MftA

Investigation of Solvent Hydron Exchange in the Reaction Catalyzed by the Antibiotic Resistance Protein Cfr

Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface

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