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Periodontal therapeutics: Current host‐modulation agents and future directions

Periodontology 2000, 2020-02, Vol.82 (1), p.186-204

2020

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Dose‐response assessment of chemically modified curcumin in experimental periodontitis

Journal of periodontology (1970), 2019-05, Vol.90 (5), p.535-545

2019

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Non-antibacterial tetracycline formulations: host-modulators in the treatment of periodontitis and relevant systemic diseases

International dental journal, 2016-06, Vol.66 (3), p.127-135

2016

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Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non‐antimicrobial tetracycline analog (COL‐3) in a metastatic prostate cancer model

International journal of cancer, 2002-03, Vol.98 (2), p.297-309

2002

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Inhibition of Matrix Metalloproteinase‐Mediated Periodontal Bone Loss in Rats: A Comparison of 6 Chemically Modified Tetracyclines

Journal of periodontology (1970), 2002-07, Vol.73 (7), p.726-734

2002

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A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras

Molecular carcinogenesis, 2018-09, Vol.57 (9), p.1130-1143

2018

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Loss of alveolar bone density in postmenopausal, osteopenic women is associated with circulating levels of gelatinases

Journal of periodontal research, 2019-10, Vol.54 (5), p.525-532

2019

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Association of Gingival Crevicular Fluid Biomarkers During Periodontal Maintenance With Subsequent Progressive Periodontitis

Journal of periodontology (1970), 2010-02, Vol.81 (2), p.251-259

2010

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Subantimicrobial‐Dose Doxycycline Modulates Gingival Crevicular Fluid Biomarkers of Periodontitis in Postmenopausal Osteopenic Women

Journal of periodontology (1970), 2008-08, Vol.79 (8), p.1409-1418

2008

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The Association Between Clinical and Radiographic Periodontitis Measurements During Periodontal Maintenance

Journal of periodontology (1970), 2013-10, Vol.84 (10), p.1382-1390

2013

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Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: Effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 γ2-chain

Wound repair and regeneration, 2002-01, Vol.10 (1), p.38-51

2002

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Subantimicrobial Dose Doxycycline Efficacy as a Matrix Metalloproteinase Inhibitor in Chronic Periodontitis Patients Is Enhanced When Combined With a Non‐Steroidal Anti‐Inflammatory Drug

Journal of periodontology (1970), 2004-03, Vol.75 (3), p.453-463

2004

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Effects of scaling and root planing and sub-antimicrobial dose doxycycline on oral and systemic biomarkers of disease in patients with both chronic periodontitis and coronary artery disease

Journal of clinical periodontology, 2007-08, Vol.34 (8), p.673-681

2007

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Subantimicrobial dose doxycycline effects on alveolar bone loss in post-menopausal women

Journal of clinical periodontology, 2007-09, Vol.34 (9), p.776-787

2007

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Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy

Periodontology 2000, 2000-10, Vol.24 (1), p.226-238

2000

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Subantimicrobial Dose Doxycycline Effects on Osteopenic Bone Loss: Microbiologic Results

Journal of periodontology (1970), 2007-08, Vol.78 (8), p.1590-1601

2007

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Efficacy of sub-antimicrobial dose doxycycline in post-menopausal women: clinical outcomes

Journal of clinical periodontology, 2007-09, Vol.34 (9), p.768-775

2007

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Scientific Basis of a Matrix Metalloproteinase-8 Specific Chair-side Test for Monitoring Periodontal and Peri-implant Health and Disease

Annals of the New York Academy of Sciences, 1999-06, Vol.878 (1), p.130-140

1999

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MMP-Mediated Events in Diabetes

Annals of the New York Academy of Sciences, 1999-06, Vol.878 (1), p.311-334

1999

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A Combination of a Chemically Modified Doxycycline and a Bisphosphonate Synergistically Inhibits Endotoxin‐Induced Periodontal Breakdown in Rats

Journal of periodontology (1970), 2001-08, Vol.72 (8), p.1069-1077

2001

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Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva

Journal of clinical periodontology, 1995-02, Vol.22 (2), p.100-109

1995

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Inflammatory mediator release following bone grafting in humans: a pilot study

Journal of clinical periodontology, 2007-09, Vol.34 (9), p.797-804

2007

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Doxycycline and Chemically Modified Tetracyclines Inhibit Gelatinase A (MMP-2) Gene Expression in Human Skin Keratinocytes

Annals of the New York Academy of Sciences, 1994-09, Vol.732 (1), p.140-151

1994

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Blocking Periodontal Disease Progression by Inhibiting Tissue‐Destructive Enzymes: A Potential Therapeutic Role for Tetracyclines and Their Chemically‐Modified Analogs

Journal of periodontology (1970), 1993-08, Vol.64 (8S), p.819-827

1993

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Adjunctive treatment with subantimicrobial doses of doxycycline: effects on gingival fluid collagenase activity and attachment loss in adult periodontitis

Journal of clinical periodontology, 2001-02, Vol.28 (2), p.146-156

2001

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Periodontal therapeutics: Current host‐modulation agents and future directions

Dose‐response assessment of chemically modified curcumin in experimental periodontitis

Non-antibacterial tetracycline formulations: host-modulators in the treatment of periodontitis and relevant systemic diseases

Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non‐antimicrobial tetracycline analog (COL‐3) in a metastatic prostate cancer model

Inhibition of Matrix Metalloproteinase‐Mediated Periodontal Bone Loss in Rats: A Comparison of 6 Chemically Modified Tetracyclines

A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras

Loss of alveolar bone density in postmenopausal, osteopenic women is associated with circulating levels of gelatinases

Association of Gingival Crevicular Fluid Biomarkers During Periodontal Maintenance With Subsequent Progressive Periodontitis

Subantimicrobial‐Dose Doxycycline Modulates Gingival Crevicular Fluid Biomarkers of Periodontitis in Postmenopausal Osteopenic Women

The Association Between Clinical and Radiographic Periodontitis Measurements During Periodontal Maintenance

Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: Effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 γ2-chain

Subantimicrobial Dose Doxycycline Efficacy as a Matrix Metalloproteinase Inhibitor in Chronic Periodontitis Patients Is Enhanced When Combined With a Non‐Steroidal Anti‐Inflammatory Drug

Effects of scaling and root planing and sub-antimicrobial dose doxycycline on oral and systemic biomarkers of disease in patients with both chronic periodontitis and coronary artery disease

Subantimicrobial dose doxycycline effects on alveolar bone loss in post-menopausal women

Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy

Subantimicrobial Dose Doxycycline Effects on Osteopenic Bone Loss: Microbiologic Results

Efficacy of sub-antimicrobial dose doxycycline in post-menopausal women: clinical outcomes

Scientific Basis of a Matrix Metalloproteinase-8 Specific Chair-side Test for Monitoring Periodontal and Peri-implant Health and Disease

MMP-Mediated Events in Diabetes

A Combination of a Chemically Modified Doxycycline and a Bisphosphonate Synergistically Inhibits Endotoxin‐Induced Periodontal Breakdown in Rats

Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva

Inflammatory mediator release following bone grafting in humans: a pilot study

Doxycycline and Chemically Modified Tetracyclines Inhibit Gelatinase A (MMP-2) Gene Expression in Human Skin Keratinocytes

Blocking Periodontal Disease Progression by Inhibiting Tissue‐Destructive Enzymes: A Potential Therapeutic Role for Tetracyclines and Their Chemically‐Modified Analogs

Adjunctive treatment with subantimicrobial doses of doxycycline: effects on gingival fluid collagenase activity and attachment loss in adult periodontitis

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