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Inhibitory Effect of Valproic Acid on Cytochrome P450 2C9 Activity in Epilepsy Patients

Basic & clinical pharmacology & toxicology, 2007-06, Vol.100 (6), p.383-386

2007

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Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Epilepsia (Copenhagen), 2007-07, Vol.48 (7), p.1223-1244

2007

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Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

Journal of neurochemistry, 2012-06, Vol.121 (5), p.818-829

2012

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A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

Epilepsia (Copenhagen), 2012-01, Vol.53 (1), p.134-146

2012

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Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Journal of neurochemistry, 2009-11, Vol.111 (4), p.976-987

2009

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Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo

Hepatology (Baltimore, Md.), 2010-02, Vol.51 (2), p.603-614

2010

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Valproic acid for the treatment of myeloid malignancies

Cancer, 2007-09, Vol.110 (5), p.943-954

2007

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Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells

British journal of pharmacology, 2008-02, Vol.153 (4), p.657-668

2008

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Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro

Epilepsia (Copenhagen), 2010-03, Vol.51 (3), p.423-431

2010

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Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine

Annals of neurology, 2008-08, Vol.64 (2), p.200-211

2008

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Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid

International journal of cancer, 2005-04, Vol.114 (3), p.380-386

2005

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Fetal Exposure to GABA‐Acting Antiepileptic Drugs Generates Hippocampal and Cortical Dysplasias

Epilepsia (Copenhagen), 2007-04, Vol.48 (4), p.684-693

2007

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Histone Deacetylase Inhibitors Promote Osteoblast Maturation

Journal of bone and mineral research, 2005-12, Vol.20 (12), p.2254-2263

2005

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Is Sodium Valproate, an HDAC inhibitor, associated with reduced risk of stroke and myocardial infarction? A nested case-control study

Pharmacoepidemiology and drug safety, 2014-07, Vol.23 (7), p.759-767

2014

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Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein‐Barr virus‐positive epithelial malignancies and mediates enhanced cell death

International journal of cancer, 2010-05, Vol.126 (10), p.2479-2489

2010

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Hdac inhibitor treatment of hepatoma cells induces both trail-independent apoptosis and restoration of sensitivity to TRAIL

Hepatology (Baltimore, Md.), 2006-03, Vol.43 (3), p.425-434

2006

Volltextzugriff (PDF)

In vivo anti‐myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor

British journal of haematology, 2008-11, Vol.143 (4), p.520-531

2008

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Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics

Journal of clinical pharmacy and therapeutics, 2012-12, Vol.37 (6), p.693-697

2012

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Influence of Major Antiepileptic Drugs on Attention, Reaction Time, and Speed of Information Processing: Results from a Randomized, Double‐blind, Placebo‐controlled Withdrawal Study of Seizure‐free Epilepsy Patients Receiving Monotherapy

Epilepsia (Copenhagen), 2006-12, Vol.47 (12), p.2038-2045

2006

Volltextzugriff (PDF)

Valproic acid: Growth inhibition of head and neck cancer by induction of terminal differentiation and senescence

Head & neck, 2012-03, Vol.34 (3), p.344-353

2012

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Characterization of a Lamotrigine‐Resistant Kindled Model of Epilepsy in Mice: Evaluation of Drug Resistance Mechanisms

Basic & clinical pharmacology & toxicology, 2014-11, Vol.115 (5), p.373-378

2014

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Valproic acid increases SMN levels in spinal muscular atrophy patient cells

Annals of neurology, 2003-11, Vol.54 (5), p.647-654

2003

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Reversible Effects of Antiepileptic Drugs on Reproductive Endocrine Function in Men and Women with Epilepsy—A Prospective Randomized Double‐Blind Withdrawal Study

Epilepsia (Copenhagen), 2007-10, Vol.48 (10), p.1875-1882

2007

Volltextzugriff (PDF)

Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid

Basic & clinical pharmacology & toxicology, 2014-08, Vol.115 (2), p.216-221

2014

Volltextzugriff (PDF)

Levetiracetam, Phenytoin, and Valproate Act Differently on Rat Bone Mass, Structure, and Metabolism

Epilepsia (Copenhagen), 2007-10, Vol.48 (10), p.1850-1860

2007

Volltextzugriff (PDF)

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Inhibitory Effect of Valproic Acid on Cytochrome P450 2C9 Activity in Epilepsy Patients

Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo

Valproic acid for the treatment of myeloid malignancies

Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells

Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro

Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine

Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid

Fetal Exposure to GABA‐Acting Antiepileptic Drugs Generates Hippocampal and Cortical Dysplasias

Histone Deacetylase Inhibitors Promote Osteoblast Maturation

Is Sodium Valproate, an HDAC inhibitor, associated with reduced risk of stroke and myocardial infarction? A nested case-control study

Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein‐Barr virus‐positive epithelial malignancies and mediates enhanced cell death

Hdac inhibitor treatment of hepatoma cells induces both trail-independent apoptosis and restoration of sensitivity to TRAIL

In vivo anti‐myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor

Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics

Influence of Major Antiepileptic Drugs on Attention, Reaction Time, and Speed of Information Processing: Results from a Randomized, Double‐blind, Placebo‐controlled Withdrawal Study of Seizure‐free Epilepsy Patients Receiving Monotherapy

Valproic acid: Growth inhibition of head and neck cancer by induction of terminal differentiation and senescence

Characterization of a Lamotrigine‐Resistant Kindled Model of Epilepsy in Mice: Evaluation of Drug Resistance Mechanisms

Valproic acid increases SMN levels in spinal muscular atrophy patient cells

Reversible Effects of Antiepileptic Drugs on Reproductive Endocrine Function in Men and Women with Epilepsy—A Prospective Randomized Double‐Blind Withdrawal Study

Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid

Levetiracetam, Phenytoin, and Valproate Act Differently on Rat Bone Mass, Structure, and Metabolism

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