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Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment‐resistant bipolar depression

British journal of clinical pharmacology, 2012-08, Vol.74 (2), p.304-314

2012

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Rapid clinical induction of bupropion hydroxylation by metamizole in healthy Chinese men

British journal of clinical pharmacology, 2012-12, Vol.74 (6), p.999-1004

2012

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Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

Journal of mass spectrometry., 2011-08, Vol.46 (8), p.725-733

2011

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Metabolism of TM‐2, a potential antitumor drug, in rats by using LC–MS

Journal of separation science, 2014-03, Vol.37 (6), p.625-629

2014

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Tentative identification of new metabolites of epimedin C by liquid chromatography–mass spectrometry

Journal of separation science, 2011-11, Vol.34 (22), p.3200-3207

2011

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The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy : Studies in stereoselective hydroxylation and population pharmacokinetics

Epilepsia (Copenhagen), 1998-12, Vol.39 (12), p.1317-1323

1998

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Is Bupropion a More Specific Substrate for Porcine CYP2E than Chlorzoxazone and p‐Nitrophenol?

Basic & clinical pharmacology & toxicology, 2007-09, Vol.101 (3), p.159-162

2007

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Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first‐pass metabolism, CYP2D6 genotype and formulation‐dependent bioavailability

British journal of clinical pharmacology, 2003-12, Vol.56 (6), p.639-652

2003

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A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer

British journal of clinical pharmacology, 2000-05, Vol.49 (5), p.485-488

2000

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Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans

Hepatology (Baltimore, Md.), 1997-10, Vol.26 (4), p.957-961

1997

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Chlorpropamide 2‐hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism

British journal of clinical pharmacology, 2005-05, Vol.59 (5), p.552-563

2005

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Effects of CYP2D6 Genotypes on Plasma Concentrations of Risperidone and Enantiomers of 9-Hydroxyrisperidone in Japanese Patients with Schizophrenia

Journal of clinical pharmacology, 2003-02, Vol.43 (2), p.122-127

2003

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Relationship between Type A and B personality and debrisoquine hydroxylation capacity

British journal of clinical pharmacology, 2004-06, Vol.57 (6), p.785-789

2004

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Reliability of the omeprazole hydroxylation index for CYP2C19 phenotyping: possible effect of age, liver disease and length of therapy

British journal of clinical pharmacology, 1999-01, Vol.47 (1), p.115-119

1999

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Polyhydroxylated C60, Fullerenol, a Novel Free-radical Trapper, Prevented Hydrogen Peroxide- and Cumene Hydroperoxide-elicited Changes in Rat Hippocampus In-vitro

Journal of pharmacy and pharmacology, 1997-04, Vol.49 (4), p.438-445

1997

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Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19

British journal of clinical pharmacology, 2002-04, Vol.53 (4), p.393-397

2002

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Inhibitors of alprazolam metabolism in vitro: effect of serotonin‐ reuptake‐inhibitor antidepressants, ketoconazole and quinidine

British journal of clinical pharmacology, 1994-07, Vol.38 (1), p.23-31

1994

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Pharmacokinetics of SDZ RAD and cyclosporin including their metabolites in seven kidney graft patients after the first dose of SDZ RAD

British journal of clinical pharmacology, 2000-11, Vol.50 (5), p.449-454

2000

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Hydroxylated metabolites of thalidomide : Formation in-vitro and in-vivo in man

Journal of pharmacy and pharmacology, 1998-12, Vol.50 (12), p.1409-1416

1998

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Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

British journal of clinical pharmacology, 1997-03, Vol.43 (3), p.245-252

1997

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Disposition of clozapine in man: lack of association with debrisoquine and S‐mephenytoin hydroxylation polymorphisms

British journal of clinical pharmacology, 1994-01, Vol.37 (1), p.71-74

1994

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Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19

British journal of clinical pharmacology, 1997-08, Vol.44 (2), p.186-189

1997

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The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes

British journal of clinical pharmacology, 1994-07, Vol.38 (1), p.15-22

1994

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Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics

British journal of pharmacology, 1993-09, Vol.110 (1), p.482-490

1993

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Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine

British journal of clinical pharmacology, 1991-06, Vol.31 (6), p.635-642

1991

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Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment‐resistant bipolar depression

Rapid clinical induction of bupropion hydroxylation by metamizole in healthy Chinese men

Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

Metabolism of TM‐2, a potential antitumor drug, in rats by using LC–MS

Tentative identification of new metabolites of epimedin C by liquid chromatography–mass spectrometry

The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy : Studies in stereoselective hydroxylation and population pharmacokinetics

Is Bupropion a More Specific Substrate for Porcine CYP2E than Chlorzoxazone and p‐Nitrophenol?

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first‐pass metabolism, CYP2D6 genotype and formulation‐dependent bioavailability

A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer

Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans

Chlorpropamide 2‐hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism

Effects of CYP2D6 Genotypes on Plasma Concentrations of Risperidone and Enantiomers of 9-Hydroxyrisperidone in Japanese Patients with Schizophrenia

Relationship between Type A and B personality and debrisoquine hydroxylation capacity

Reliability of the omeprazole hydroxylation index for CYP2C19 phenotyping: possible effect of age, liver disease and length of therapy

Polyhydroxylated C60, Fullerenol, a Novel Free-radical Trapper, Prevented Hydrogen Peroxide- and Cumene Hydroperoxide-elicited Changes in Rat Hippocampus In-vitro

Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19

Inhibitors of alprazolam metabolism in vitro: effect of serotonin‐ reuptake‐inhibitor antidepressants, ketoconazole and quinidine

Pharmacokinetics of SDZ RAD and cyclosporin including their metabolites in seven kidney graft patients after the first dose of SDZ RAD

Hydroxylated metabolites of thalidomide : Formation in-vitro and in-vivo in man

Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

Disposition of clozapine in man: lack of association with debrisoquine and S‐mephenytoin hydroxylation polymorphisms

Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19

The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes

Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics

Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine

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