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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

The FEBS journal, 2020-05, Vol.287 (10), p.2118-2133

2020

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GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

The European journal of neuroscience, 2023-02, Vol.57 (3), p.527-546

2023

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Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Epilepsia (Copenhagen), 2020-09, Vol.61 (9), p.2022-2034

2020

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Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy

Epilepsia (Copenhagen), 2023-01, Vol.64 (1), p.e1-e8

2023

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Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy

Experimental physiology, 2021-08, Vol.106 (8), p.1814-1828

2021

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Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Journal of neurochemistry, 2020-08, Vol.154 (3), p.284-300

2020

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Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

Clinical and experimental pharmacology & physiology, 2023-09, Vol.50 (9), p.749-756

2023

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The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes

Journal of neurochemistry, 2024-06, Vol.168 (6), p.1045-1059

2024

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Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa

British journal of dermatology (1951), 2024-09, Vol.191 (4), p.568

2024

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The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Developmental psychobiology, 2023-01, Vol.65 (1), p.e22353-n/a

2023

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Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

CNS neuroscience & therapeutics, 2024-04, Vol.30 (4), p.e14524-n/a

2024

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Valproate treatment induces age‐ and sex‐dependent neuronal activity changes according to a patch clamp study

Developmental neurobiology (Hoboken, N.J.), 2024-01, Vol.84 (1), p.32-43

2024

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Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co‐culture model of inflammation

Epilepsia (Copenhagen), 2014-01, Vol.55 (1), p.184-192

2014

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Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Journal of biomedical materials research. Part B, Applied biomaterials, 2022-12, Vol.110 (12), p.2636-2648

2022

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Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Epilepsia (Copenhagen), 2019-02, Vol.60 (2), p.315-321

2019

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Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

Fundamental & clinical pharmacology, 2022-02, Vol.36 (1), p.133-142

2022

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Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

CNS neuroscience & therapeutics, 2024-02, Vol.30 (2), p.e14583-n/a

2024

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

The EMBO journal, 2001-12, Vol.20 (24), p.6969-6978

2001

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Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Journal of cellular physiology, 2017-05, Vol.232 (5), p.1176-1186

2017

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Differential effects of inhibitors of PTZ‐induced kindling on glutamate transporters and enzyme expression

Clinical and experimental pharmacology & physiology, 2021-12, Vol.48 (12), p.1662-1673

2021

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The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

The EMBO journal, 2003-07, Vol.22 (13), p.3411-3420

2003

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The potential protective effect of liraglutide on valproic acid induced liver injury in rats: Targeting HMGB1/RAGE axis and RIPK3/MLKL mediated necroptosis

Cell biochemistry and function, 2023-12, Vol.41 (8), p.1209-1219

2023

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Reversal of Valproate‐Induced Major Salivary Gland Changes By Moringa Oleifera Extract in Rats

Chemistry & biodiversity, 2024-05, Vol.21 (5), p.e202301959-n/a

2024

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Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

Journal of neurochemistry, 2012-06, Vol.121 (5), p.818-829

2012

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Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up‐regulation of neurotrophic factors

British journal of pharmacology, 2015-08, Vol.172 (16), p.4200-4215

2015

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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy

Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy

Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes

Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa

The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

Valproate treatment induces age‐ and sex‐dependent neuronal activity changes according to a patch clamp study

Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co‐culture model of inflammation

Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Differential effects of inhibitors of PTZ‐induced kindling on glutamate transporters and enzyme expression

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

The potential protective effect of liraglutide on valproic acid induced liver injury in rats: Targeting HMGB1/RAGE axis and RIPK3/MLKL mediated necroptosis

Reversal of Valproate‐Induced Major Salivary Gland Changes By Moringa Oleifera Extract in Rats

Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up‐regulation of neurotrophic factors

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