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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

The FEBS journal, 2020-05, Vol.287 (10), p.2118-2133

2020

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Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma

Fundamental & clinical pharmacology, 2021-08, Vol.35 (4), p.690-699

2021

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Persistent treatment resistance in genetic generalized epilepsy: A long‐term outcome study in a tertiary epilepsy center

Epilepsia (Copenhagen), 2020-11, Vol.61 (11), p.2452-2460

2020

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Lacosamide effects on placental carriers of essential compounds in comparison with valproate: Studies in perfused human placentas

Epilepsia (Copenhagen), 2022-11, Vol.63 (11), p.2949-2957

2022

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Association of BDNF risk variant and dorsolateral cortical thickness with long‐term treatment response to valproate in type I bipolar disorder: An exploratory study

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2024-04, Vol.195 (3), p.e32966-n/a

2024

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GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

The European journal of neuroscience, 2023-02, Vol.57 (3), p.527-546

2023

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Antiepileptic drugs: Impacts on human serum paraoxonase‐1

Journal of biochemical and molecular toxicology, 2017-06, Vol.31 (6), p.n/a

2017

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Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Epilepsia (Copenhagen), 2020-09, Vol.61 (9), p.2022-2034

2020

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Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy

Epilepsia (Copenhagen), 2023-01, Vol.64 (1), p.e1-e8

2023

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Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Journal of neurochemistry, 2020-08, Vol.154 (3), p.284-300

2020

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Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy

Experimental physiology, 2021-08, Vol.106 (8), p.1814-1828

2021

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Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

Clinical and experimental pharmacology & physiology, 2023-09, Vol.50 (9), p.749-756

2023

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Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

CNS neuroscience & therapeutics, 2024-04, Vol.30 (4), p.e14524-n/a

2024

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Inhibitory Effect of Valproic Acid on Cytochrome P450 2C9 Activity in Epilepsy Patients

Basic & clinical pharmacology & toxicology, 2007-06, Vol.100 (6), p.383-386

2007

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The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Developmental psychobiology, 2023-01, Vol.65 (1), p.e22353-n/a

2023

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Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co‐culture model of inflammation

Epilepsia (Copenhagen), 2014-01, Vol.55 (1), p.184-192

2014

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Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Journal of biomedical materials research. Part B, Applied biomaterials, 2022-12, Vol.110 (12), p.2636-2648

2022

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Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Epilepsia (Copenhagen), 2007-07, Vol.48 (7), p.1223-1244

2007

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Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Epilepsia (Copenhagen), 2019-02, Vol.60 (2), p.315-321

2019

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Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

Fundamental & clinical pharmacology, 2022-02, Vol.36 (1), p.133-142

2022

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SMA valiant trial: A prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy

Muscle & nerve, 2014-02, Vol.49 (2), p.187-192

2014

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Differential effects of inhibitors of PTZ‐induced kindling on glutamate transporters and enzyme expression

Clinical and experimental pharmacology & physiology, 2021-12, Vol.48 (12), p.1662-1673

2021

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

The EMBO journal, 2001-12, Vol.20 (24), p.6969-6978

2001

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Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

CNS neuroscience & therapeutics, 2024-02, Vol.30 (2), p.e14583-n/a

2024

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Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

Journal of cellular physiology, 2017-05, Vol.232 (5), p.1176-1186

2017

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Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma

Persistent treatment resistance in genetic generalized epilepsy: A long‐term outcome study in a tertiary epilepsy center

Lacosamide effects on placental carriers of essential compounds in comparison with valproate: Studies in perfused human placentas

Association of BDNF risk variant and dorsolateral cortical thickness with long‐term treatment response to valproate in type I bipolar disorder: An exploratory study

GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder

Antiepileptic drugs: Impacts on human serum paraoxonase‐1

Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice

Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy

Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

Treatment effects of the combination of ceftriaxone and valproic acid on neuronal and behavioural functions in a rat model of epilepsy

Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy

Valproic acid ameliorates cauda equina injury by suppressing HDAC2‐mediated ferroptosis

Inhibitory Effect of Valproic Acid on Cytochrome P450 2C9 Activity in Epilepsy Patients

The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of autism

Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co‐culture model of inflammation

Sustained release of sulforaphane by bioactive extracellular vesicles for neuroprotective effect on chick model

Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Comparative efficacy of valnoctamide and sec‐butylpropylacetamide (SPD) in terminating nerve agent–induced seizures in pediatric rats

Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice

SMA valiant trial: A prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy

Differential effects of inhibitors of PTZ‐induced kindling on glutamate transporters and enzyme expression

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Differential inflammation responses determine the variable phenotypes of epilepsy induced by GABRG2 mutations

Valproic Acid and Lithium Meditate Anti‐Inflammatory Effects by Differentially Modulating Dendritic Cell Differentiation and Function

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