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Taking Complement to the Clinic - has the Time Finally Come?

Scandinavian journal of immunology, 2009-06, Vol.69 (6), p.471-478

2009

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Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)‐prone NZB/NZW mice by a new radial enzyme diffusion assay

Clinical and experimental immunology, 1997-05, Vol.108 (2), p.220-226

1997

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Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: comparison of rush and conventional immunotherapy

Clinical and experimental allergy, 1995-09, Vol.25 (9), p.828-838

1995

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Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency1

Clinical and experimental immunology, 2020-12, Vol.202 (3), p.379-383

2020

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Further studies of the down‐regulation by Factor I of the C3b feedback cycle using endotoxin as a soluble activator and red cells as a source of CR1 on sera of different complotype

Clinical and experimental immunology, 2016-01, Vol.183 (1), p.150-156

2016

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The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen‐ and antigen‐stimulated human peripheral blood mononuclear cell cultures

Clinical and experimental immunology, 1995-02, Vol.99 (2), p.160-167

1995

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Complotype affects the extent of down‐regulation by Factor I of the C3b feedback cycle in vitro

Clinical and experimental immunology, 2015-08, Vol.181 (2), p.314-322

2015

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Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers

Immunology, 1990-09, Vol.71 (1), p.1-9

1990

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The effect of antibody isotype and antigenic epitope density on the complement‐fixing activity of immune complexes: a systematic study using chimaeric anti‐NIP antibodies with human Fc regions

Clinical and experimental immunology, 1991-04, Vol.84 (1), p.1-8

1991

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The paraproteins in systemic capillary leak syndrome

Clinical and experimental immunology, 1993-09, Vol.93 (3), p.424-429

1993

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A systematic study of neutrophil degranulation and respiratory burst in vitro by defined immune complexes

Clinical and experimental immunology, 1995-09, Vol.101 (3), p.507-514

1995

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Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross‐linking of Fcα receptors (FcαR) with a monoclonal antibody, MIP8a

Clinical and experimental immunology, 2000-07, Vol.121 (1), p.106-111

2000

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Glycosylation of IgA is required for optimal activation of the alternative complement pathway by immune complexes

Immunology, 1994, Vol.81 (1), p.137-141

1994

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Venom-specific IgG antibodies in bee and wasp allergy: lack of correlation with protection from stings

Clinical and experimental allergy, 1993-08, Vol.23 (8), p.647-660

1993

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The interaction of streptococcal inhibitor of complement (SIC) and its proteolytic fragments with the human beta defensins

Immunology, 2004-04, Vol.111 (4), p.444-452

2004

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Streptococcal inhibitor of complement (SIC) inhibits the membrane attack complex by preventing uptake of C567 onto cell membranes

Immunology, 2001-07, Vol.103 (3), p.390-398

2001

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The in vivo destruction of antigen—a tool for probing and modulating an autoimmune response

Clinical and experimental immunology, 1996-11, Vol.106 (2), p.187-189

LACHMANN, P. J.

1996

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CR1 stump peptide and terminal complement complexes are found in the glomeruli of lupus nephritis patients

Clinical and experimental immunology, 1996-09, Vol.105 (3), p.497-503

1996

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Oligodendrocytes lack glycolipid anchored proteins which protect them against complement lysis. Restoration of resistance to lysis by incorporation of CD59

Immunology, 1992-05, Vol.76 (1), p.140-145

1992

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A comparative study of IgG subclass antibodies in patients allergic to wasp or bee venom

Allergy (Copenhagen), 1994-04, Vol.49 (4), p.272-280

1994

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Bispecific antibody: a tool for diagnosis and treatment of disease

Clinical and experimental immunology, 1990-03, Vol.79 (3), p.315-321

1990

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The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

Clinical and experimental immunology, 1996-11, Vol.106 (2), p.243-252

1996

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Family studies of erythrocyte complement receptor type 1 levels: reduced levels in patients with SLE are acquired, not inherited

Clinical and experimental immunology, 1985-03, Vol.59 (3), p.547-554

1985

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Difficulties in the ascertainment of C9 deficiency: lessons to be drawn from a compound heterozygote C9‐deficient subject

Clinical and experimental immunology, 1997-06, Vol.108 (3), p.500-506

1997

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Neutrophil Fcγ and complement receptors involved in binding soluble IgG immune complexes and in specific granule release induced by soluble IgG immune complexes

European journal of immunology, 1997-10, Vol.27 (10), p.2514-2523

1997

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Taking Complement to the Clinic - has the Time Finally Come?

Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)‐prone NZB/NZW mice by a new radial enzyme diffusion assay

Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: comparison of rush and conventional immunotherapy

Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency1

Further studies of the down‐regulation by Factor I of the C3b feedback cycle using endotoxin as a soluble activator and red cells as a source of CR1 on sera of different complotype

The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen‐ and antigen‐stimulated human peripheral blood mononuclear cell cultures

Complotype affects the extent of down‐regulation by Factor I of the C3b feedback cycle in vitro

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers

The effect of antibody isotype and antigenic epitope density on the complement‐fixing activity of immune complexes: a systematic study using chimaeric anti‐NIP antibodies with human Fc regions

The paraproteins in systemic capillary leak syndrome

A systematic study of neutrophil degranulation and respiratory burst in vitro by defined immune complexes

Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross‐linking of Fcα receptors (FcαR) with a monoclonal antibody, MIP8a

Glycosylation of IgA is required for optimal activation of the alternative complement pathway by immune complexes

Venom-specific IgG antibodies in bee and wasp allergy: lack of correlation with protection from stings

The interaction of streptococcal inhibitor of complement (SIC) and its proteolytic fragments with the human beta defensins

Streptococcal inhibitor of complement (SIC) inhibits the membrane attack complex by preventing uptake of C567 onto cell membranes

The in vivo destruction of antigen—a tool for probing and modulating an autoimmune response

CR1 stump peptide and terminal complement complexes are found in the glomeruli of lupus nephritis patients

Oligodendrocytes lack glycolipid anchored proteins which protect them against complement lysis. Restoration of resistance to lysis by incorporation of CD59

A comparative study of IgG subclass antibodies in patients allergic to wasp or bee venom

Bispecific antibody: a tool for diagnosis and treatment of disease

The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

Family studies of erythrocyte complement receptor type 1 levels: reduced levels in patients with SLE are acquired, not inherited

Difficulties in the ascertainment of C9 deficiency: lessons to be drawn from a compound heterozygote C9‐deficient subject

Neutrophil Fcγ and complement receptors involved in binding soluble IgG immune complexes and in specific granule release induced by soluble IgG immune complexes

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