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GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease

Inflammatory bowel diseases, 2023-12, Vol.29 (12), p.1981-1989

2023

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The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Journal of food biochemistry, 2018-10, Vol.42 (5), p.e12624-n/a

2018

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Fatty acid taste quality information via GPR120 in the anterior tongue of mice

Acta Physiologica, 2019-05, Vol.226 (1), p.e13215-n/a

2019

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Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

Nutrition reviews, 2022-01, Vol.80 (2), p.187-199

2022

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GPR120 facilitates cholesterol efflux in macrophages through activation of AMPK signaling pathway

The FEBS journal, 2020-12, Vol.287 (23), p.5080-5095

2020

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The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

EMBO molecular medicine, 2018-03, Vol.10 (3), p.n/a

2018

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Cyclooxygenase‐2 induction in macrophages is modulated by docosahexaenoic acid via interactions with free fatty acid receptor 4 (FFA4)

The FASEB journal, 2013-12, Vol.27 (12), p.4987-4997

2013

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Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Acta pharmacologica Sinica, 2021-02, Vol.42 (2), p.252-263

2021

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Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

British journal of pharmacology, 2006-07, Vol.148 (5), p.619-628

2006

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CD36 and GPR120 mediated orogustatory perception of dietary lipids and its physiological implication in the pygmy mouse Mus booduga

Journal of animal physiology and animal nutrition, 2022-11, Vol.106 (6), p.1408-1419

2022

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Diphenyl Ether Derivatives as Novel GPR120 Agonists for the Treatment of Type 2 Diabetes Mellitus

Chemistry & biodiversity, 2023-01, Vol.20 (1), p.e202200814-n/a

2023

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Long noncoding RNA LINC00662‐miR‐15b‐5p mediated GPR120 dysregulation contributes to osteoarthritis

Pathology international, 2020-03, Vol.70 (3), p.155-165

2020

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EPA blocks TNF‐α‐induced inhibition of sugar uptake in Caco‐2 cells via GPR120 and AMPK

Journal of cellular physiology, 2018-03, Vol.233 (3), p.2426-2433

2018

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Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression

Acta pharmacologica Sinica, 2017-02, Vol.38 (2), p.192-200

2017

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Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells

Diabetes, obesity & metabolism, 2014-11, Vol.16 (11), p.1128-1139

2014

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Lipopolysaccharide inhibits GPR120 expression in macrophages via Toll‐like receptor 4 and p38 MAPK activation

Cell biology international, 2020-01, Vol.44 (1), p.89-97

2020

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GPR120 is not required for ω‐3 PUFAs‐induced cell growth inhibition and apoptosis in breast cancer cells

Cell biology international, 2018-02, Vol.42 (2), p.180-186

2018

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Therapeutic effect of omega‐3 fatty acids on T cell‐mediated autoimmune diseases

Microbiology and immunology, 2020-08, Vol.64 (8), p.563-569

2020

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Effects of obesity/fatty acids on the expression of GPR120

Molecular nutrition & food research, 2014-09, Vol.58 (9), p.1852-1860

2014

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The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

FEBS open bio, 2021-11, Vol.11 (11), p.3081-3089

2021

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FFA1‐selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models

British journal of pharmacology, 2013-04, Vol.168 (7), p.1570-1583

2013

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Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases

Pharmacology research & perspectives, 2018-12, Vol.6 (6), p.e00438-n/a

2018

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Effect of dietary Schizochytrium microalga oil on selected markers of low-grade inflammation in rats

Journal of animal physiology and animal nutrition, 2016-12, Vol.100 (6), p.1169-1178

2016

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Screening for G-protein-coupled receptors expressed in mouse taste papillae

Flavour and fragrance journal, 2011-07, Vol.26 (4), p.223-230

2011

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G-蛋白偶联受体GPR120分子模建研究

Hua hsüeh hsüeh pao, 2009, Vol.67 (14), p.1553-1558

陆绍永蒋勇军俞庆森邹建卫

2009

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GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease

The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Fatty acid taste quality information via GPR120 in the anterior tongue of mice

Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

GPR120 facilitates cholesterol efflux in macrophages through activation of AMPK signaling pathway

The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

Cyclooxygenase‐2 induction in macrophages is modulated by docosahexaenoic acid via interactions with free fatty acid receptor 4 (FFA4)

Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

CD36 and GPR120 mediated orogustatory perception of dietary lipids and its physiological implication in the pygmy mouse Mus booduga

Diphenyl Ether Derivatives as Novel GPR120 Agonists for the Treatment of Type 2 Diabetes Mellitus

Long noncoding RNA LINC00662‐miR‐15b‐5p mediated GPR120 dysregulation contributes to osteoarthritis

EPA blocks TNF‐α‐induced inhibition of sugar uptake in Caco‐2 cells via GPR120 and AMPK

Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression

Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells

Lipopolysaccharide inhibits GPR120 expression in macrophages via Toll‐like receptor 4 and p38 MAPK activation

GPR120 is not required for ω‐3 PUFAs‐induced cell growth inhibition and apoptosis in breast cancer cells

Therapeutic effect of omega‐3 fatty acids on T cell‐mediated autoimmune diseases

Effects of obesity/fatty acids on the expression of GPR120

The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

FFA1‐selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models

Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases

Effect of dietary Schizochytrium microalga oil on selected markers of low-grade inflammation in rats

Screening for G-protein-coupled receptors expressed in mouse taste papillae

G-蛋白偶联受体GPR120分子模建研究

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