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Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses

Cell cycle (Georgetown, Tex.), 2015-09, Vol.14 (18), p.2881-2885

2015

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The transcription factor p53: Not a repressor, solely an activator

Cell cycle (Georgetown, Tex.), 2014-10, Vol.13 (19), p.3037-3058

2014

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Flavonoids as potential reactivators of structural mutation p53Y220C by computational and cell-based studies

Journal of biomolecular structure & dynamics, 2024-12, Vol.42 (18), p.9602-9613

2024

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Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

Cell cycle (Georgetown, Tex.), 2011-05, Vol.10 (10), p.1679-1689

2011

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p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis

Cell cycle (Georgetown, Tex.), 2016-12, Vol.15 (23), p.3210-3219

2016

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Molecular docking and molecular dynamics simulation analysis of bioactive compounds of Cichorium intybus L. seed against hepatocellular carcinoma

Journal of biomolecular structure & dynamics, 2024-11, Vol.42 (17), p.9133-9144

2024

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Sirtuin 1 inhibition: a promising avenue to suppress cancer progression through small inhibitors design

Journal of biomolecular structure & dynamics, 2024-12, Vol.42 (19), p.9825-9841

2024

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Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73

Cell cycle (Georgetown, Tex.), 2010-11, Vol.9 (22), p.4584-4591

2010

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BRCT domains: Easy as one, two, three

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (15), p.2461-2470

2011

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Computational-based drug design of novel small molecules targeting p53-MDMX interaction

Journal of biomolecular structure & dynamics, 2024-09, Vol.42 (13), p.6678-6687

2024

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Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

Cell cycle (Georgetown, Tex.), 2008-08, Vol.7 (15), p.2441-2443

2008

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Ubiquitination and Degradation of Mutant p53

Molecular and Cellular Biology, 2007-12, Vol.27 (23), p.8284-8295

2007

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Structural modulation of p53TAD1-TAZ2 complex upon mutations and post-translational modification

Journal of biomolecular structure & dynamics, 2023-01, Vol.41 (1), p.176-185

2023

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Lysines in the tetramerization domain of p53 selectively modulate G1 arrest

Cell cycle (Georgetown, Tex.), 2016-06, Vol.15 (11), p.1425-1438

2016

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CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA

Cell cycle (Georgetown, Tex.), 2018-01, Vol.17 (5), p.557-567

2018

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Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity

Molecular and Cellular Biology, 2005-07, Vol.25 (13), p.5389-5395

2005

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p73 tumor suppressor protein: A close relative of p53 not only in structure but also in anti-cancer approach?

Cell cycle (Georgetown, Tex.), 2010-02, Vol.9 (4), p.720-728

2010

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A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

Molecular and Cellular Biology, 2001-03, Vol.21 (5), p.1874-1887

2001

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Regulation of Human p53 Activity and Cell Localization by Alternative Splicing

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7987-7997

2004

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How phosphorylation controls p53

Cell cycle (Georgetown, Tex.), 2011-03, Vol.10 (6), p.916-921

2011

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Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

Molecular and Cellular Biology, 2012-12, Vol.32 (23), p.4821-4832

2012

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Molecular Basis for the Inhibition of p53 by Mdmx

Cell cycle (Georgetown, Tex.), 2007-10, Vol.6 (19), p.2386-2392

2007

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p53 Tumor Suppressor Protein Stability and Transcriptional Activity Are Targeted by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factor 3

Molecular and Cellular Biology, 2014-02, Vol.34 (3), p.386-399

2014

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Promising disruptors of p53-MDM2 dimerization from some medicinal plant phytochemicals: a molecular modeling study

Journal of biomolecular structure & dynamics, 2023-08, Vol.41 (12), p.5817-5826

2023

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How Many Mutant p53 Molecules Are Needed To Inactivate a Tetramer?

Molecular and Cellular Biology, 2004-04, Vol.24 (8), p.3536-3551

2004

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Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses

The transcription factor p53: Not a repressor, solely an activator

Flavonoids as potential reactivators of structural mutation p53Y220C by computational and cell-based studies

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis

Molecular docking and molecular dynamics simulation analysis of bioactive compounds of Cichorium intybus L. seed against hepatocellular carcinoma

Sirtuin 1 inhibition: a promising avenue to suppress cancer progression through small inhibitors design

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73

BRCT domains: Easy as one, two, three

Computational-based drug design of novel small molecules targeting p53-MDMX interaction

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

Ubiquitination and Degradation of Mutant p53

Structural modulation of p53TAD1-TAZ2 complex upon mutations and post-translational modification

Lysines in the tetramerization domain of p53 selectively modulate G1 arrest

CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA

Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity

p73 tumor suppressor protein: A close relative of p53 not only in structure but also in anti-cancer approach?

A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

Regulation of Human p53 Activity and Cell Localization by Alternative Splicing

How phosphorylation controls p53

Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

Molecular Basis for the Inhibition of p53 by Mdmx

p53 Tumor Suppressor Protein Stability and Transcriptional Activity Are Targeted by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factor 3

Promising disruptors of p53-MDM2 dimerization from some medicinal plant phytochemicals: a molecular modeling study

How Many Mutant p53 Molecules Are Needed To Inactivate a Tetramer?

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