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Regulation of the human TRAIL gene

Cancer biology & therapy, 2012-10, Vol.13 (12), p.1143-1151

2012

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Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering

Cancer biology & therapy, 2023-12, Vol.24 (1), p.2176692-2176692

2023

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Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target

Expert opinion on therapeutic targets, 2019-04, Vol.23 (4), p.295-307

2019

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Distinct Signaling Pathways in TRAIL- versus Tumor Necrosis Factor-Induced Apoptosis

Molecular and Cellular Biology, 2006-11, Vol.26 (21), p.8136-8148

2006

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Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2

Cancer biology & therapy, 2010-12, Vol.10 (11), p.1201-1214

2010

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Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway

Autoimmunity (Chur, Switzerland), 2022-01, Vol.55 (1), p.52-64

2022

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Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response

Autophagy, 2016-12, Vol.12 (12), p.2451-2466

2016

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DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer

Cancer biology & therapy, 2014-01, Vol.15 (12), p.1658-1666

2014

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Transmembrane TNF-dependent uptake of anti-TNF antibodies

mAbs, 2017-05, Vol.9 (4), p.680-695

2017

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The role of TRADD in death receptor signaling

Cell cycle (Georgetown, Tex.), 2012-03, Vol.11 (5), p.871-876

2012

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The three Rs along the TRAIL: Resistance, re-sensitization and reactive oxygen species (ROS)

Free radical research, 2012-08, Vol.46 (8), p.996-1003

2012

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ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer

Cancer biology & therapy, 2015, Vol.16 (8), p.1194-1204

2015

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Low-dose 5-fluorouracil sensitizes HepG2 cells to TRAIL through TRAIL receptor DR5 and survivin-dependent mechanisms

Journal of chemotherapy (Florence), 2017-05, Vol.29 (3), p.179-188

2017

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TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways

Molecular and cellular biology, 2020-04, Vol.40 (9)

2020

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TRAIL induces endocytosis of its death receptors in MDA-MB-231 breast cancer cells

Cancer biology & therapy, 2009-05, Vol.8 (10), p.917-922

2009

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Combined modality therapy with TRAIL or agonistic death receptor antibodies

Cancer biology & therapy, 2011-03, Vol.11 (5), p.431-449

2011

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TRAIL receptor signaling and therapeutics

Expert opinion on therapeutic targets, 2010-10, Vol.14 (10), p.1091-1108

2010

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Neo-DREAM study investigating Daromun for the treatment of clinical stage IIIB/C melanoma

Future oncology (London, England), 2019-11, Vol.15 (32), p.3665-3674

2019

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Anti-TNF-α agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls

Immunotherapy, 2010-11, Vol.2 (6), p.817-833

2010

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IκB Kinase ε Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation

Molecular and Cellular Biology, 2012-12, Vol.32 (23), p.4756-4768

2012

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The role of PAK1 in the sensitivity of kidney epithelial cells to ischemia-like conditions

Cell cycle (Georgetown, Tex.), 2019-03, Vol.18 (5), p.596-604

2019

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Interfering hsa_circ_0073748 alleviates caerulein-induced ductal cell injury in acute pancreatitis by inhibiting miR-132-3p/TRAF3/NF-κB pathway

Cell cycle (Georgetown, Tex.), 2022-01, Vol.21 (2), p.172-186

2022

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2’-Hydroxyflavanone Induces Apoptosis of Human Osteosarcoma 143 B Cells by Activating the Extrinsic TRAIL- and Intrinsic Mitochondria-Mediated Pathways

Nutrition and cancer, 2014-05, Vol.66 (4), p.625-635

2014

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Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo

Cancer biology & therapy, 2021-12, Vol.22 (10-12), p.607-618

2021

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Tumor necrosis factor, tumor necrosis factor inhibition, and cancer risk

Current medical research and opinion, 2015-03, Vol.31 (3), p.557-574

2015

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Regulation of the human TRAIL gene

Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering

Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target

Distinct Signaling Pathways in TRAIL- versus Tumor Necrosis Factor-Induced Apoptosis

Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2

Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway

Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response

DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer

Transmembrane TNF-dependent uptake of anti-TNF antibodies

The role of TRADD in death receptor signaling

The three Rs along the TRAIL: Resistance, re-sensitization and reactive oxygen species (ROS)

ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer

Low-dose 5-fluorouracil sensitizes HepG2 cells to TRAIL through TRAIL receptor DR5 and survivin-dependent mechanisms

TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways

TRAIL induces endocytosis of its death receptors in MDA-MB-231 breast cancer cells

Combined modality therapy with TRAIL or agonistic death receptor antibodies

TRAIL receptor signaling and therapeutics

Neo-DREAM study investigating Daromun for the treatment of clinical stage IIIB/C melanoma

Anti-TNF-α agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls

IκB Kinase ε Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation

The role of PAK1 in the sensitivity of kidney epithelial cells to ischemia-like conditions

Interfering hsa_circ_0073748 alleviates caerulein-induced ductal cell injury in acute pancreatitis by inhibiting miR-132-3p/TRAF3/NF-κB pathway

2’-Hydroxyflavanone Induces Apoptosis of Human Osteosarcoma 143 B Cells by Activating the Extrinsic TRAIL- and Intrinsic Mitochondria-Mediated Pathways

Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo

Tumor necrosis factor, tumor necrosis factor inhibition, and cancer risk

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