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The transcriptional program, functional heterogeneity, and clinical targeting of mast cells

The Journal of experimental medicine, 2017-09, Vol.214 (9), p.2491-2506

2017

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The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

Immunological reviews, 2012-11, Vol.250 (1), p.277-302

2012

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Mechanisms of vitamin D3 metabolite repression of IgE-dependent mast cell activation

Journal of allergy and clinical immunology, 2014-05, Vol.133 (5), p.1356-1364.e14

2014

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Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis

Science advances, 2018-11, Vol.4 (11), p.eaat3834

2018

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Molecular basis of cytokine receptor activation

IUBMB life, 2010-07, Vol.62 (7), p.509-518

2010

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Targeting IL-5Rα with antibody-conjugates reveals a strategy for imaging and therapy for invasive bladder cancer

Oncoimmunology, 2017-10, Vol.6 (10), p.e1331195-e1331195

2017

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Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases

Immunity (Cambridge, Mass.), 2019-11, Vol.51 (5), p.949-965.e6

2019

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Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

Science translational medicine, 2021-09, Vol.13 (612), p.eabd5524

2021

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Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor

British journal of haematology, 2013-05, Vol.161 (3), p.389-401

2013

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IgE receptor of mast cells signals mediator release and inflammation via adaptor protein 14-3-3ζ

Journal of allergy and clinical immunology, 2023-09, Vol.152 (3), p.725-735.e10

2023

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Translating the biology of β common receptor-engaging cytokines into clinical medicine

Journal of allergy and clinical immunology, 2023-02, Vol.151 (2), p.324-344

2023

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Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade

Journal of allergy and clinical immunology, 2024-03, Vol.153 (3), p.672-683.e6

2024

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Targeting the human βc receptor inhibits inflammatory myeloid cells and lung injury caused by acute cigarette smoke exposure

Respirology (Carlton, Vic.), 2022-08, Vol.27 (8), p.617-629

2022

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The βc receptor family – Structural insights and their functional implications

Cytokine (Philadelphia, Pa.), 2015-08, Vol.74 (2), p.247-258

2015

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Ywhaz/14-3-3ζ Deletion Improves Glucose Tolerance Through a GLP-1-Dependent Mechanism

Endocrinology (Philadelphia), 2016-07, Vol.157 (7), p.2649-2659

2016

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Anti‐βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model

Allergy (Copenhagen), 2020-02, Vol.75 (2), p.475-478

2020

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A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

Angiogenesis (London), 2016-10, Vol.19 (4), p.463-486

2016

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The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

mAbs, 2018-10, Vol.10 (7), p.1018-12

2018

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GM‐CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid‐derived suppressor cells in vitro

Clinical & translational immunology, 2016-12, Vol.5 (12), p.e119-n/a

2016

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Interleukin‐3‐mediated regulation of β‐catenin in myeloid transformation and acute myeloid leukemia

Journal of leukocyte biology, 2014-07, Vol.96 (1), p.83-91

2014

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IL-3 receptor expression, regulation and function in cells of the Vasculature

Immunology and cell biology, 1996-02, Vol.74 (1), p.1-7

1996

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Mechanism of Activation of the GM‐CSF, IL‐3, and IL‐5 Family of Receptors

Stem cells (Dayton, Ohio), 1998-01, Vol.16 (5), p.301-313

1998

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Evidence that vitamin D3 promotes mast cell–dependent reduction of chronic UVB-induced skin pathology in mice

The Journal of experimental medicine, 2010-03, Vol.207 (3), p.455-463

2010

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The transcriptional program, functional heterogeneity, and clinical targeting of mast cells

The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

Mechanisms of vitamin D3 metabolite repression of IgE-dependent mast cell activation

Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis

TLR7 gain-of-function genetic variation causes human lupus

Molecular basis of cytokine receptor activation

Targeting IL-5Rα with antibody-conjugates reveals a strategy for imaging and therapy for invasive bladder cancer

Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor

IgE receptor of mast cells signals mediator release and inflammation via adaptor protein 14-3-3ζ

Translating the biology of β common receptor-engaging cytokines into clinical medicine

Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade

Targeting the human βc receptor inhibits inflammatory myeloid cells and lung injury caused by acute cigarette smoke exposure

The βc receptor family – Structural insights and their functional implications

Ywhaz/14-3-3ζ Deletion Improves Glucose Tolerance Through a GLP-1-Dependent Mechanism

Anti‐βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

GM‐CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid‐derived suppressor cells in vitro

Interleukin‐3‐mediated regulation of β‐catenin in myeloid transformation and acute myeloid leukemia

IL-3 receptor expression, regulation and function in cells of the Vasculature

Mechanism of Activation of the GM‐CSF, IL‐3, and IL‐5 Family of Receptors

Evidence that vitamin D3 promotes mast cell–dependent reduction of chronic UVB-induced skin pathology in mice

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