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Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial

The Lancet (British edition), 2021-06, Vol.397 (10290), p.2169-2181

2021

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How Aggregate Safety Assessment Planning Supports Investigational New Drug Safety Reporting Decisions

Therapeutic innovation & regulatory science, 2024-07, Vol.58 (4), p.579-590

2024

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Aggregate Safety Assessment Planning for the Drug Development Life-Cycle

Therapeutic innovation & regulatory science, 2021-07, Vol.55 (4), p.717-732

2021

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Interdisciplinary Safety Evaluation for Learning and Decision-Making

Therapeutic innovation & regulatory science, 2021-07, Vol.55 (4), p.705-716

2021

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A Framework for Safety Evaluation Throughout the Product Development Life-Cycle

Therapeutic innovation & regulatory science, 2020-07, Vol.54 (4), p.821-830

2020

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Polymeric Immunoglobulin Receptor in Intestinal Immune Defense against the Lumen-Dwelling Protozoan Parasite Giardia

Journal of Immunology, 2006-11, Vol.177 (9), p.6281-6290

2006

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Global Regulatory Landscape for Aggregate Safety Assessments: Recent Developments and Future Directions

Therapeutic innovation & regulatory science, 2020-03, Vol.54 (2), p.447-461

2020

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Enteric flora and lymphocyte-derived cytokines determine expression of heat shock proteins in mouse colonic epithelial cells

Gastroenterology (New York, N.Y. 1943), 2003-05, Vol.124 (5), p.1395-1407

2003

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Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies

Journal of allergy and clinical immunology, 2023-01, Vol.151 (1), p.172-181

2023

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Aggregate IND Safety Reporting for Smaller Companies and Programs

Therapeutic innovation & regulatory science, 2024-03, Vol.58 (2), p.368-379

2024

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MMR vaccination, ileal lymphoid nodular hyperplasia, and pervasive developmental disorder

The Lancet (British edition), 2002-06, Vol.359 (9323), p.2051-2052

2002

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Surgical stress shifts the intestinal Eschericia coli population to that of a more adherent phenotype: Role in barrier regulation

Surgery, 2001-07, Vol.130 (1), p.65-73

2001

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Increased Type 1 Fimbrial Expression among Commensal Escherichia coli Isolates in the Murine Cecum following Catabolic Stress

Infection and Immunity, 1999-02, Vol.67 (2), p.745-753

1999

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MMR vaccination, ileal lymphoid nodular hyperplasia, and pervasive develop-mental disorder

The Lancet (British edition), 2002-06, Vol.359 (9323), p.2051

2002

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Altered hepatic transport of immunoglobulin A in mice lacking the J chain

The Journal of experimental medicine, 1995-12, Vol.182 (6), p.1905-1911

1995

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Filtered supernatant of lactobacillus GG (LGG) prevents Crohn's disease (CD) mucosa adherent-E. coli induced alterations in paracellular permeability

Gastroenterology (New York, N.Y. 1943), 2003-04, Vol.124 (4), p.A476-A476

2003

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Lack of association of secretory component with IgA in J chain-deficient mice

The Journal of immunology (1950), 1996-07, Vol.157 (2), p.750-754

1996

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Genetic relatedness of mucosa-associated and nonadherent commensal E. coli strains isolated from Crohns disease(CD) patients

Gastroenterology (New York, N.Y. 1943), 2003-04, Vol.124 (4), p.A320-A320

2003

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Increased numbers of mucosa-associated Escherichia coli in Crohn's disease

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A521-A521

2001

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Long noncoding RNAs regulate adipogenesis

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (9), p.3387-3392

2013

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Assessment of polymicrobial interactions in bacterial isolates from transfused platelet units associated with sepsis

Transfusion (Philadelphia, Pa.), 2022-12, Vol.62 (12), p.2458-2463

2022

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Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury

JAMA : the journal of the American Medical Association, 2020-09, Vol.324 (10), p.961

2020

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Randomized Trial of Platelet-Transfusion Thresholds in Neonates

The New England journal of medicine, 2019-01, Vol.380 (3), p.242-251

2019

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Co-Culture of Acinetobacter calcoaceticus-baumannii complex and Staphylococcus saprophyticus Supports Simple Point Contamination Model in Recent Cases of Transfusion-Related Sepsis

American journal of clinical pathology, 2020-10, Vol.154 (Supplement_1), p.S14-S14

2020

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Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years

JAMA pediatrics, 2014-08, Vol.168 (8), p.729

2014

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Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial

How Aggregate Safety Assessment Planning Supports Investigational New Drug Safety Reporting Decisions

Aggregate Safety Assessment Planning for the Drug Development Life-Cycle

Interdisciplinary Safety Evaluation for Learning and Decision-Making

A Framework for Safety Evaluation Throughout the Product Development Life-Cycle

Polymeric Immunoglobulin Receptor in Intestinal Immune Defense against the Lumen-Dwelling Protozoan Parasite Giardia

Global Regulatory Landscape for Aggregate Safety Assessments: Recent Developments and Future Directions

Enteric flora and lymphocyte-derived cytokines determine expression of heat shock proteins in mouse colonic epithelial cells

Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies

Aggregate IND Safety Reporting for Smaller Companies and Programs

MMR vaccination, ileal lymphoid nodular hyperplasia, and pervasive developmental disorder

Surgical stress shifts the intestinal Eschericia coli population to that of a more adherent phenotype: Role in barrier regulation

Increased Type 1 Fimbrial Expression among Commensal Escherichia coli Isolates in the Murine Cecum following Catabolic Stress

MMR vaccination, ileal lymphoid nodular hyperplasia, and pervasive develop-mental disorder

Altered hepatic transport of immunoglobulin A in mice lacking the J chain

Filtered supernatant of lactobacillus GG (LGG) prevents Crohn's disease (CD) mucosa adherent-E. coli induced alterations in paracellular permeability

Lack of association of secretory component with IgA in J chain-deficient mice

Genetic relatedness of mucosa-associated and nonadherent commensal E. coli strains isolated from Crohns disease(CD) patients

Increased numbers of mucosa-associated Escherichia coli in Crohn's disease

Long noncoding RNAs regulate adipogenesis

Assessment of polymicrobial interactions in bacterial isolates from transfused platelet units associated with sepsis

Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury

Randomized Trial of Platelet-Transfusion Thresholds in Neonates

Co-Culture of Acinetobacter calcoaceticus-baumannii complex and Staphylococcus saprophyticus Supports Simple Point Contamination Model in Recent Cases of Transfusion-Related Sepsis

Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years

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