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Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes

Molecular biology and evolution, 2024-02, Vol.41 (2)

2024

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INPS: predicting the impact of non-synonymous variations on protein stability from sequence

Bioinformatics, 2015-09, Vol.31 (17), p.2816-2821

2015

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Comprehensive large-scale assessment of intrinsic protein disorder

Bioinformatics (Oxford, England), 2015-01, Vol.31 (2), p.201-208

2015

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A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

Human molecular genetics, 2015-04, Vol.24 (7), p.1929-1944

2015

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Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome

JNCI : Journal of the National Cancer Institute, 2018-12, Vol.110 (12), p.1418-1421

2018

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G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms

Carcinogenesis (New York), 2011-03, Vol.32 (3), p.271-278

2011

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p53 N-terminal phosphorylation: a defining layer of complex regulation

Carcinogenesis (New York), 2012-08, Vol.33 (8), p.1441-1449

2012

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Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

Cardiovascular research, 2011-06, Vol.90 (3), p.538-545

2011

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Undifferentiated State Induced by Rb‐p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts

Stem cells (Dayton, Ohio), 2015-05, Vol.33 (5), p.1657-1669

2015

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Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites

Human molecular genetics, 2014-06, Vol.23 (11), p.2847-2857

2014

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A survey of available tools and web servers for analysis of protein-protein interactions and interfaces

Briefings in bioinformatics, 2009-05, Vol.10 (3), p.217-232

2009

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Automated Quantitative Analysis (AQUA) of In Situ Protein Expression, Antibody Concentration, and Prognosis

JNCI : Journal of the National Cancer Institute, 2005-12, Vol.97 (24), p.1808-1815

2005

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An in silico algorithm for identifying stabilizing pockets in proteins: test case, the Y220C mutant of the p53 tumor suppressor protein

Protein engineering, design and selection, 2016-09, Vol.29 (9), p.377-390

2016

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The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs

Human molecular genetics, 2016-04, Vol.25 (8), p.1517-1527

2016

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Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis

Toxicological Sciences, 2012-03, Vol.126 (1), p.60-71

2012

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A half-site of the p53-binding site on the keratin 14 promoter is specifically activated by p63

Journal of biochemistry (Tokyo), 2012-07, Vol.152 (1), p.99-110

2012

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Enhanced antigen detection in immunohistochemical staining using a ‘digitized’ chimeric antibody

Protein engineering, design and selection, 2016-01, Vol.29 (1), p.11-21

2016

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The code structure of the p53 DNA-binding domain and the prognosis of breast cancer patients

Bioinformatics, 2013-11, Vol.29 (22), p.2822-2825

2013

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The relevance of protein–protein interactions for p53 function: the CPE contribution

Protein engineering, design and selection, 2011, Vol.24 (1-2), p.41-51

2011

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Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core

Protein engineering, design and selection, 2009-07, Vol.22 (7), p.421-430

2009

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An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors

The journal of clinical endocrinology and metabolism, 2001-10, Vol.86 (10), p.4970-4973

2001

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Influence of Magnesium Ion on the Binding of p53 DNA-Binding Domain to DNA-Response Elements

Journal of biochemistry (Tokyo), 2009-07, Vol.146 (1), p.77-85

2009

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From peptides to proteins: lessons from my years at the Centre for Protein Engineering

Protein engineering, design and selection, 2011, Vol.24 (1-2), p.241-245

Friedler, Assaf

2011

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Effect of Metal Ion on the Structural Stability of Tumour Suppressor Protein p53 DNA-Binding Domain

Journal of biochemistry (Tokyo), 2009-08, Vol.146 (2), p.193-200

2009

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Molecular Genetic Evidence for Subtypes of Oligoastrocytomas

Journal of neuropathology and experimental neurology, 1997-10, Vol.56 (10), p.1098-1104

1997

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Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes

INPS: predicting the impact of non-synonymous variations on protein stability from sequence

Comprehensive large-scale assessment of intrinsic protein disorder

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome

G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms

p53 N-terminal phosphorylation: a defining layer of complex regulation

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

Undifferentiated State Induced by Rb‐p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts

Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites

A survey of available tools and web servers for analysis of protein-protein interactions and interfaces

Automated Quantitative Analysis (AQUA) of In Situ Protein Expression, Antibody Concentration, and Prognosis

An in silico algorithm for identifying stabilizing pockets in proteins: test case, the Y220C mutant of the p53 tumor suppressor protein

The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs

Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis

A half-site of the p53-binding site on the keratin 14 promoter is specifically activated by p63

Enhanced antigen detection in immunohistochemical staining using a ‘digitized’ chimeric antibody

The code structure of the p53 DNA-binding domain and the prognosis of breast cancer patients

The relevance of protein–protein interactions for p53 function: the CPE contribution

Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core

An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors

Influence of Magnesium Ion on the Binding of p53 DNA-Binding Domain to DNA-Response Elements

From peptides to proteins: lessons from my years at the Centre for Protein Engineering

Effect of Metal Ion on the Structural Stability of Tumour Suppressor Protein p53 DNA-Binding Domain

Molecular Genetic Evidence for Subtypes of Oligoastrocytomas

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