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Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide

Protein engineering, design and selection, 2006-12, Vol.19 (12), p.547-554

2006

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Differential Expression of CYP1A, 2B, and 3A Genes in the F344 Rat following Exposure to a Polybrominated Diphenyl Ether Mixture or Individual Components

Toxicological sciences, 2005-11, Vol.88 (1), p.127-133

2005

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Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Toxicological sciences, 2001-05, Vol.61 (1), p.76-82

2001

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Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Toxicological sciences, 2009-03, Vol.108 (1), p.69-80

2009

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Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury

The Journal of nutrition, 2009-12, Vol.139 (12), p.2252-2256

2009

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The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus

Mutagenesis, 2013-03, Vol.28 (2), p.161-169

2013

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Differential effects of oltipraz on CYP1A and CYP2B in rat lung

Carcinogenesis (New York), 2001-01, Vol.22 (1), p.49-55

2001

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Induction of hepatic cytochromes P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls

Toxicological sciences, 1999, Vol.47 (1), p.52-61

1999

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Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice

Carcinogenesis (New York), 2001-01, Vol.22 (1), p.73-82

2001

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The Effects of Triclosan on Puberty and Thyroid Hormones in Male Wistar Rats

Toxicological sciences, 2009-01, Vol.107 (1), p.56-64

2009

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Inhibition of apoptosis in rat hepatocytes treated with `non-dioxin-like' polychlorinated biphenyls

Carcinogenesis (New York), 2001-10, Vol.22 (10), p.1601-1605

2001

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Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbital and its plasma concentration in rats

Journal of pharmacy and pharmacology, 2004-03, Vol.56 (3), p.401-405

2004

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Dose-Response Modeling of Cytochrome P450 Induction in Rats by Octamethylcyclotetrasiloxane

Toxicological sciences, 2002-06, Vol.67 (2), p.159-172

2002

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Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis

Journal of pharmacy and pharmacology, 2006-06, Vol.58 (6), p.859-866

2006

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Involvement of a Cytochrome P450 System in Microsomal Debromination of α-(Bromisovaleryl)urea

Journal of pharmacy and pharmacology, 1996-09, Vol.48 (9), p.930-932

1996

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Altered expression and glucocorticoid-inducibility of Hepatic CYP3A and CYP2B enzymes in male rats fed diets containing soy protein isolate

The Journal of nutrition, 1999-11, Vol.129 (11), p.1958-1965

1999

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In Vitro Zonation and Toxicity in a Hepatocyte Bioreactor

Toxicological sciences, 2005-03, Vol.84 (1), p.110-119

2005

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Developmental Exposure to Brominated Diphenyl Ethers Results in Thyroid Hormone Disruption

Toxicological sciences, 2002-03, Vol.66 (1), p.105-116

2002

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Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1

Carcinogenesis (New York), 1997-04, Vol.18 (4), p.801-810

1997

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Intracerebroventricularly and systemically delivered inhibitor of brain CYP2B (C8-Xanthate), even following chlorpyrifos exposure, reduces chlorpyrifos activation and toxicity in male rats

Toxicological sciences, 2014-07, Vol.140 (1), p.49-60

2014

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Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats

Bioscience, biotechnology, and biochemistry, 2014-06, Vol.78 (6), p.1060-1066

2014

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Serum Testosterone Is Reduced Following Short-Term Phytofluene, Lycopene, or Tomato Powder Consumption in F344 Rats

The Journal of nutrition, 2006-11, Vol.136 (11), p.2813-2819

2006

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Stereoselective N-Demethylation of Chlorpheniramine by Rat-liver Microsomes and the Involvement of Cytochrome P450 Isozymes

Journal of pharmacy and pharmacology, 1997-03, Vol.49 (3), p.257-262

1997

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Polychlorinated Biphenyls–Modulated Tumorigenesis in Sprague–Dawley Rats: Correlation with Mixed Function Oxidase Activities and Superoxide (O2•−) Formation Potentials and Implied Mode of Action

Toxicological sciences, 2007-08, Vol.98 (2), p.375-394

2007

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Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat

Bioscience, biotechnology, and biochemistry, 2014, Vol.78 (9), p.1550-1559

2014

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Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide

Differential Expression of CYP1A, 2B, and 3A Genes in the F344 Rat following Exposure to a Polybrominated Diphenyl Ether Mixture or Individual Components

Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury

The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus

Differential effects of oltipraz on CYP1A and CYP2B in rat lung

Induction of hepatic cytochromes P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls

Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice

The Effects of Triclosan on Puberty and Thyroid Hormones in Male Wistar Rats

Inhibition of apoptosis in rat hepatocytes treated with `non-dioxin-like' polychlorinated biphenyls

Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbital and its plasma concentration in rats

Dose-Response Modeling of Cytochrome P450 Induction in Rats by Octamethylcyclotetrasiloxane

Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis

Involvement of a Cytochrome P450 System in Microsomal Debromination of α-(Bromisovaleryl)urea

Altered expression and glucocorticoid-inducibility of Hepatic CYP3A and CYP2B enzymes in male rats fed diets containing soy protein isolate

In Vitro Zonation and Toxicity in a Hepatocyte Bioreactor

Developmental Exposure to Brominated Diphenyl Ethers Results in Thyroid Hormone Disruption

Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1

Intracerebroventricularly and systemically delivered inhibitor of brain CYP2B (C8-Xanthate), even following chlorpyrifos exposure, reduces chlorpyrifos activation and toxicity in male rats

Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats

Serum Testosterone Is Reduced Following Short-Term Phytofluene, Lycopene, or Tomato Powder Consumption in F344 Rats

Stereoselective N-Demethylation of Chlorpheniramine by Rat-liver Microsomes and the Involvement of Cytochrome P450 Isozymes

Polychlorinated Biphenyls–Modulated Tumorigenesis in Sprague–Dawley Rats: Correlation with Mixed Function Oxidase Activities and Superoxide (O2•−) Formation Potentials and Implied Mode of Action

Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat

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