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Designing More Efficient Preclinical Experiments: A Simulation Study in Chemotherapy-Induced Myelosupression

Toxicological sciences, 2016-03, Vol.150 (1), p.109-116

2016

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Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

Brain (London, England : 1878), 2020-02, Vol.143 (2), p.407-429

2020

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The frontline of alternatives to animal testing: novel in vitro skin model application in drug development and evaluation

Toxicological sciences, 2023-11, Vol.196 (2), p.152-169

2023

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Is it time for a paradigm shift in drug research and development in endometriosis/adenomyosis?

Human reproduction update, 2018-09, Vol.24 (5), p.577-598

2018

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Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-11, Vol.71 (11), p.1395-1406

2016

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Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (11), p.1898-1910

2021

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Of mice and human embryos: is there an ethically preferred order of preclinical research on new assisted reproductive technologies?

Human reproduction (Oxford), 2018-09, Vol.33 (9), p.1581-1585

2018

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Simple Test of Manual Dexterity Can Help to Identify Persons at High Risk for Neurodegenerative Diseases in the Community

The journals of gerontology. Series A, Biological sciences and medical sciences, 2017-01, Vol.72 (1), p.75-81

2017

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Subcutaneous cardioverter defibrillator has longer time to therapy but is less cardiotoxic than transvenous cardioverter defibrillator. Study carried out in a preclinical porcine model

Europace (London, England), 2018-05, Vol.20 (5), p.873-879

2018

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Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades

Journal of neuropathology and experimental neurology, 2014-11, Vol.73 (11), p.1078-1090

2014

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Thoracolaparoscopic dissection of esophageal lymph nodes without esophagectomy is feasible in human cadavers and safe in a porcine survival study

Diseases of the esophagus, 2016-08, Vol.29 (6), p.649-655

2016

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Preclinical safety evaluation of human gene therapy products

Toxicological sciences, 1999, Vol.47 (1), p.9-15

1999

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Episodic memory loss is related to hippocampal-mediated β-amyloid deposition in elderly subjects

Brain (London, England : 1878), 2009-05, Vol.132 (5), p.1310-1323

2009

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EEG evidence of compensatory mechanisms in preclinical Alzheimer's disease

Brain (London, England : 1878), 2019-07, Vol.142 (7), p.2096-2112

2019

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Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques

The journals of gerontology. Series A, Biological sciences and medical sciences, 2021-04, Vol.76 (4), p.552-560

2021

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Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings

Brain (London, England : 1878), 2015-12, Vol.138 (Pt 12), p.3747-3759

2015

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Preclinical workup using long-read amplicon sequencing provides families with de novo pathogenic variants access to universal preimplantation genetic testing

Human reproduction (Oxford), 2023-03, Vol.38 (3), p.511-519

2023

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Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes

Brain (London, England : 1878), 2024-03, Vol.147 (3), p.936-948

2024

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Screening for preclinical parenchymal lung disease in rheumatoid arthritis

Rheumatology (Oxford, England), 2022-08, Vol.61 (8), p.3234-3245

2022

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Preanalytical Sample Handling Conditions and Their Effects on the Human Serum Metabolome in Epidemiologic Studies

American journal of epidemiology, 2021-03, Vol.190 (3), p.459-467

2021

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Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies: Beyond a Simple Count

Endocrine reviews, 2021-10, Vol.42 (5), p.584-604

2021

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A practical blueprint to systematically study life-long health consequences of novel medically assisted reproductive treatments

Human reproduction (Oxford), 2018-05, Vol.33 (5), p.784-792

2018

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Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines

Neuro-oncology (Charlottesville, Va.), 2021-12, Vol.23 (12), p.2066-2075

2021

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Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity

Journal of antimicrobial chemotherapy, 2008-06, Vol.61 (6), p.1281-1287

2008

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In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease

Human molecular genetics, 2018-11, Vol.27 (22), p.3974-3985

2018

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Designing More Efficient Preclinical Experiments: A Simulation Study in Chemotherapy-Induced Myelosupression

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

The frontline of alternatives to animal testing: novel in vitro skin model application in drug development and evaluation

Is it time for a paradigm shift in drug research and development in endometriosis/adenomyosis?

Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience

Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties

Of mice and human embryos: is there an ethically preferred order of preclinical research on new assisted reproductive technologies?

Simple Test of Manual Dexterity Can Help to Identify Persons at High Risk for Neurodegenerative Diseases in the Community

Subcutaneous cardioverter defibrillator has longer time to therapy but is less cardiotoxic than transvenous cardioverter defibrillator. Study carried out in a preclinical porcine model

Combinatorial Therapy With Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades

Thoracolaparoscopic dissection of esophageal lymph nodes without esophagectomy is feasible in human cadavers and safe in a porcine survival study

Preclinical safety evaluation of human gene therapy products

Episodic memory loss is related to hippocampal-mediated β-amyloid deposition in elderly subjects

EEG evidence of compensatory mechanisms in preclinical Alzheimer's disease

Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques

Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings

Preclinical workup using long-read amplicon sequencing provides families with de novo pathogenic variants access to universal preimplantation genetic testing

Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes

Screening for preclinical parenchymal lung disease in rheumatoid arthritis

Preanalytical Sample Handling Conditions and Their Effects on the Human Serum Metabolome in Epidemiologic Studies

Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies: Beyond a Simple Count

A practical blueprint to systematically study life-long health consequences of novel medically assisted reproductive treatments

Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines

Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity

In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease

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