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Proinflammatory IgG Fc structures in patients with severe COVID-19

Nature immunology, 2021-01, Vol.22 (1), p.67-73

2021

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FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

Nature (London), 2022-06, Vol.606 (7914), p.576-584

2022

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Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

Nature medicine, 2012-09, Vol.18 (9), p.1401-1406

2012

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CCL2 recruits inflammatory monocytes to facilitate breast―tumour metastasis

Nature (London), 2011-07, Vol.475 (7355), p.222-225

2011

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TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Nature communications, 2020-06, Vol.11 (1), p.3177-3177, Article 3177

2020

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Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway

Nature (London), 2011-06, Vol.475 (7354), p.110-113

2011

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Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

Nature medicine, 2014-02, Vol.20 (2), p.143-151

2014

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Immune complexes regulate bone metabolism through FcRγ signalling

Nature communications, 2015-03, Vol.6 (1), p.6637-6637, Article 6637

2015

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Identification of Novel Human Monocyte Subsets and Evidence for Phenotypic Groups Defined by Interindividual Variations of Expression of Adhesion Molecules

Scientific reports, 2020-03, Vol.10 (1), p.4397-4397, Article 4397

2020

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Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers

Nature communications, 2021-06, Vol.12 (1), p.3451-16, Article 3451

2021

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Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

Nature (London), 2014-10, Vol.514 (7524), p.642-645

2014

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Cells of the human intestinal tract mapped across space and time

Nature (London), 2021-09, Vol.597 (7875), p.250-255

2021

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Outcomes of controlled human malaria infection after BCG vaccination

Nature communications, 2019-02, Vol.10 (1), p.874-8, Article 874

2019

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IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

Nature immunology, 2017-08, Vol.18 (8), p.889-898

2017

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The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

Cell death & disease, 2018-02, Vol.9 (3), p.266-12, Article 266

2018

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Fcγ receptors and immunomodulatory antibodies in cancer

Nature reviews. Cancer, 2024-01, Vol.24 (1), p.51-71

2024

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Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Scientific reports, 2019-03, Vol.9 (1), p.4658-4658, Article 4658

2019

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Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity

Nature communications, 2019-05, Vol.10 (1), p.2141-2141, Article 2141

2019

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TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation

Nature communications, 2021-04, Vol.12 (1), p.2299-2299, Article 2299

2021

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Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression

Nature biotechnology, 2023-05, Vol.41 (5), p.717-727

2023

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Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Nature communications, 2024-07, Vol.15 (1), p.5981-15, Article 5981

2024

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Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

Nature communications, 2015-04, Vol.6 (1), p.6866-6866, Article 6866

2015

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Immunofluorescence identifies distinct subsets of endothelial cells in the human liver

Scientific reports, 2017-03, Vol.7 (1), p.44356-44356, Article 44356

2017

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Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages

Nature communications, 2014-11, Vol.5 (1), p.5444-5444, Article 5444

2014

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Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context

Scientific reports, 2020-07, Vol.10 (1), p.11693-11693, Article 11693

2020

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Proinflammatory IgG Fc structures in patients with severe COVID-19

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

CCL2 recruits inflammatory monocytes to facilitate breast―tumour metastasis

TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway

Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

Immune complexes regulate bone metabolism through FcRγ signalling

Identification of Novel Human Monocyte Subsets and Evidence for Phenotypic Groups Defined by Interindividual Variations of Expression of Adhesion Molecules

Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

Cells of the human intestinal tract mapped across space and time

Outcomes of controlled human malaria infection after BCG vaccination

IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

Fcγ receptors and immunomodulatory antibodies in cancer

Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity

TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

Immunofluorescence identifies distinct subsets of endothelial cells in the human liver

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages

Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context

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