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Pan-KRAS inhibitors suppress proliferation through feedback regulation in pancreatic ductal adenocarcinoma

Acta pharmacologica Sinica, 2022-10, Vol.43 (10), p.2696-2708

2022

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Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes

Acta pharmacologica Sinica, 2017-01, Vol.38 (1), p.80-89

2017

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Cardioprotection of sevoflurane postconditioning by activating extracellular signal-regulated kinase 1/2 in isolated rat hearts^1

Acta pharmacologica Sinica, 2008-08, Vol.29 (8), p.931-941

2008

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Cardioprotection of sevoflurane postconditioning by activating extracellular signal‐regulated kinase 1/2 in isolated rat hearts1

Acta pharmacologica Sinica, 2008-08, Vol.29 (8), p.931-941

2008

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Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice

Acta pharmacologica Sinica, 2014-08, Vol.35 (8), p.1015-1022

2014

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Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation

Acta pharmacologica Sinica, 2016-02, Vol.37 (2), p.177-186

2016

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Ophiopogonin D maintains Ca2＋ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/ EETs and suppressing ER stress

Acta pharmacologica Sinica, 2016-03, Vol.37 (3), p.368-381

2016

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Over-expression of Gadd45a enhances radiotherapy efficacy in human Tca8113 cell line

Acta pharmacologica Sinica, 2011-02, Vol.32 (2), p.253-258

2011

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Computational drug discovery

Acta pharmacologica Sinica, 2012-09, Vol.33 (9), p.1131-1140

2012

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Association of CYP3A polymorphisms with the pharmacokinetics of cyclosporine A in early post- renal transplant recipients in China

Acta pharmacologica Sinica, 2012-12, Vol.33 (12), p.1563-1570

2012

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Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in Chinese adult renal transplant recipients

Acta pharmacologica Sinica, 2017-11, Vol.38 (11), p.1566-1579

2017

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Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels： synthesis, in vitro and in vivo evaluation

Acta pharmacologica Sinica, 2010-12, Vol.31 (12), p.1625-1634

2010

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Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model

Acta pharmacologica Sinica, 2007-03, Vol.28 (3), p.453-457

2007

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Antisense oligonucleotides targeting midkine induced apoptosis and increased chemosensitivity in hepatocellular carcinoma cells

Acta pharmacologica Sinica, 2006-12, Vol.27 (12), p.1630-1636

2006

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The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning

Acta pharmacologica Sinica, 2013-05, Vol.34 (5), p.657-666

2013

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Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors

Acta pharmacologica Sinica, 2018-02, Vol.39 (2), p.302-310

2018

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Antisense oligonucleotide targeting p53 increased apoptosis of MCF-7 cells induced by ionizing radiation

Acta pharmacologica Sinica, 2006-11, Vol.27 (11), p.1453-1458

2006

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The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation： a combined clinical study and computational system pharmacology analysis

Acta pharmacologica Sinica, 2018-02, Vol.39 (2), p.205-212

2018

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Effects of nicotine stimulation on spikes, theta frequency oscillations, and spike-theta oscillation relationship in rat medial septum diagonal band Broca slices

Acta pharmacologica Sinica, 2013-04, Vol.34 (4), p.464-472

2013

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Curcumin inhibits AP-2γ-induced apoptosis in the human malignant testicular germ cells in vitro

Acta pharmacologica Sinica, 2013-09, Vol.34 (9), p.1192-1200

2013

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Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts： partially via the PKA signaling pathway

Acta pharmacologica Sinica, 2012-07, Vol.33 (7), p.879-887

2012

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N-Acetylcysteine attenuates lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice

Acta pharmacologica Sinica, 2007-11, Vol.28 (11), p.1803-1809

2007

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Polymorphisms of angiotensin-converting enzyme （ACE） and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients

Acta pharmacologica Sinica, 2009 (9), p.1237-1244

Xiao-han FAN Yi-bo WANG Hu WANG Kai SUN Wei-li ZHANG Xiao-dong SONG Jing-zhou CHENG Hai-ying WU Xiang-liang ZHOU Ru-tai HUI

2009

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Influence of irbesartan on expression of ILK and its relationship with epithelial-mesenchymal transition in mice with unilateral ureteral obstruction

Acta pharmacologica Sinica, 2007-11, Vol.28 (11), p.1810-1818

2007

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Immune tolerance induced by adoptive transfer of dendritic cells in an insulin-dependent diabetes mellitus murine model

Acta pharmacologica Sinica, 2007, Vol.28 (1), p.98-104

2007

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Pan-KRAS inhibitors suppress proliferation through feedback regulation in pancreatic ductal adenocarcinoma

Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes

Cardioprotection of sevoflurane postconditioning by activating extracellular signal-regulated kinase 1/2 in isolated rat hearts^1

Cardioprotection of sevoflurane postconditioning by activating extracellular signal‐regulated kinase 1/2 in isolated rat hearts1

Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice

Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation

Ophiopogonin D maintains Ca2＋ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/ EETs and suppressing ER stress

Over-expression of Gadd45a enhances radiotherapy efficacy in human Tca8113 cell line

Computational drug discovery

Association of CYP3A polymorphisms with the pharmacokinetics of cyclosporine A in early post- renal transplant recipients in China

Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in Chinese adult renal transplant recipients

Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels： synthesis, in vitro and in vivo evaluation

Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model

Antisense oligonucleotides targeting midkine induced apoptosis and increased chemosensitivity in hepatocellular carcinoma cells

The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning

Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors

Antisense oligonucleotide targeting p53 increased apoptosis of MCF-7 cells induced by ionizing radiation

The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation： a combined clinical study and computational system pharmacology analysis

Effects of nicotine stimulation on spikes, theta frequency oscillations, and spike-theta oscillation relationship in rat medial septum diagonal band Broca slices

Curcumin inhibits AP-2γ-induced apoptosis in the human malignant testicular germ cells in vitro

Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts： partially via the PKA signaling pathway

N-Acetylcysteine attenuates lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice

Polymorphisms of angiotensin-converting enzyme （ACE） and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients

Influence of irbesartan on expression of ILK and its relationship with epithelial-mesenchymal transition in mice with unilateral ureteral obstruction

Immune tolerance induced by adoptive transfer of dendritic cells in an insulin-dependent diabetes mellitus murine model

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