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Impact of MDR1 and UGT Gene Polymorphisms on Sodium Valproate Plasma Concentration in Patients with Epilepsy

Clinical laboratory (Heidelberg), 2022-10, Vol.68 (10/2022)

2022

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Polymorphisms in Human MDR1 (P‐glycoprotein): Recent Advances and Clinical Relevance

Clinical pharmacology and therapeutics, 2004-01, Vol.75 (1), p.13-33

2004

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Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin

The Journal of biological chemistry, 2001-05, Vol.276 (18), p.14581-14587

2001

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Functional Polymorphisms of the Human Multidrug-Resistance Gene: Multiple Sequence Variations and Correlation of One Allele with P-Glycoprotein Expression and Activity in vivo

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (7), p.3473-3478

2000

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

Nature medicine, 2001-05, Vol.7 (5), p.584-590

2001

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The Huntington's Disease Protein Interacts with p53 and CREB-Binding Protein and Represses Transcription

Proceedings of the National Academy of Sciences - PNAS, 2000-06, Vol.97 (12), p.6763-6768

2000

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Amyloid-beta Interactions with ABC Transporters and Resistance Modifiers

Anticancer research, 2018-06, Vol.38 (6), p.3407-3410

2018

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Imaging Reversal of Multidrug Resistance in Living Mice with Bioluminescence: MDR1 P-Glycoprotein Transports Coelenterazine

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (6), p.1702-1707

2004

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Ecteinascidin 743, a Transcription-Targeted Chemotherapeutic That Inhibits MDR1 Activation

Proceedings of the National Academy of Sciences - PNAS, 2000-06, Vol.97 (12), p.6775-6779

2000

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Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.39359-39367

2001

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Transactivation of the multidrug resistance 1 gene by T-cell factor 4/β-catenin complex in early colorectal carcinogenesis

Cancer research (Chicago, Ill.), 2000-09, Vol.60 (17), p.4761-4766

2000

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Transcriptional Repression by p53 through Direct Binding to a Novel DNA Element

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27716-27720

2001

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A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

The pharmacogenomics journal, 2002, Vol.2 (3), p.191-196

2002

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Methylation-dependent Silencing of the Reduced Folate Carrier Gene in Inherently Methotrexate-resistant Human Breast Cancer Cells

The Journal of biological chemistry, 2001-10, Vol.276 (43), p.39990-40000

2001

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Induction of Wild-Type p53 Activity in Human Cancer Cells by Ribozymes That Repair Mutant p53 Transcripts

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (15), p.8490-8494

2000

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Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1

The Journal of biological chemistry, 2000-01, Vol.275 (4), p.2979-2985

2000

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Hyperthermia-induced Nuclear Translocation of Transcription Factor YB-1 Leads to Enhanced Expression of Multidrug Resistance-related ABC Transporters

The Journal of biological chemistry, 2001-07, Vol.276 (30), p.28562-28569

2001

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Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α

Journal of Zhejiang University. B. Science, 2016-09, Vol.17 (9), p.672-682

2016

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5'-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure

Nucleic acids research, 2001-09, Vol.29 (17), p.3611

2001

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Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down‐regulating multidrug resistance‐1 expression

Cancer, 2001-09, Vol.92 (6), p.1556-1566

2001

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Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance

Anticancer research, 2003-09, Vol.23 (5A), p.3607

2003

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Efficient Inhibition of P-Glycoprotein-Mediated Multidrug Resistance with a Monoclonal Antibody

Proceedings of the National Academy of Sciences - PNAS, 1992-07, Vol.89 (13), p.5824-5828

1992

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Recent Advances in P-Glycoprotein-Mediated Multidrug Resistance Reversal Mechanisms

Methods and findings in experimental and clinical pharmacology, 2007-11, Vol.29 (9), p.607-617

2007

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Drug Selection with Paclitaxel Restores Expression of Linked IL-2 Receptor γ-Chain and Multidrug Resistance (MDR1) Transgenes in Canine Bone Marrow

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.3123-3128

2002

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MDR1 P-glycoprotein Reduces Influx of Substrates without Affecting Membrane Potential

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.49053-49060

2001

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Impact of MDR1 and UGT Gene Polymorphisms on Sodium Valproate Plasma Concentration in Patients with Epilepsy

Polymorphisms in Human MDR1 (P‐glycoprotein): Recent Advances and Clinical Relevance

Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin

Functional Polymorphisms of the Human Multidrug-Resistance Gene: Multiple Sequence Variations and Correlation of One Allele with P-Glycoprotein Expression and Activity in vivo

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

The Huntington's Disease Protein Interacts with p53 and CREB-Binding Protein and Represses Transcription

Amyloid-beta Interactions with ABC Transporters and Resistance Modifiers

Imaging Reversal of Multidrug Resistance in Living Mice with Bioluminescence: MDR1 P-Glycoprotein Transports Coelenterazine

Ecteinascidin 743, a Transcription-Targeted Chemotherapeutic That Inhibits MDR1 Activation

Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1

Transactivation of the multidrug resistance 1 gene by T-cell factor 4/β-catenin complex in early colorectal carcinogenesis

Transcriptional Repression by p53 through Direct Binding to a Novel DNA Element

A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

Methylation-dependent Silencing of the Reduced Folate Carrier Gene in Inherently Methotrexate-resistant Human Breast Cancer Cells

Induction of Wild-Type p53 Activity in Human Cancer Cells by Ribozymes That Repair Mutant p53 Transcripts

Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1

Hyperthermia-induced Nuclear Translocation of Transcription Factor YB-1 Leads to Enhanced Expression of Multidrug Resistance-related ABC Transporters

Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α

5'-bis-pyrenylated oligonucleotides displaying excimer fluorescence provide sensitive probes of RNA sequence and structure

Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down‐regulating multidrug resistance‐1 expression

Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance

Efficient Inhibition of P-Glycoprotein-Mediated Multidrug Resistance with a Monoclonal Antibody

Recent Advances in P-Glycoprotein-Mediated Multidrug Resistance Reversal Mechanisms

Drug Selection with Paclitaxel Restores Expression of Linked IL-2 Receptor γ-Chain and Multidrug Resistance (MDR1) Transgenes in Canine Bone Marrow

MDR1 P-glycoprotein Reduces Influx of Substrates without Affecting Membrane Potential

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