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Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production

The Journal of biological chemistry, 2012-11, Vol.287 (48), p.40161-40172

2012

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Therapeutic siRNA silencing in inflammatory monocytes in mice

Nature biotechnology, 2011-11, Vol.29 (11), p.1005-1010

2011

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Origins of tumor-associated macrophages and neutrophils

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2491-2496

2012

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Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.E1868-E1877

2012

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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

The Journal of experimental medicine, 2015-04, Vol.212 (4), p.497-512

2015

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Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.12996-13001

2011

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Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.3955-3960

2014

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VH replacement in primary immunoglobulin repertoire diversification

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.E458-E466

2015

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Loss of NFAT5 Results in Renal Atrophy and Lack of Tonicity-Responsive Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (8), p.2392-2397

2004

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Direct in vivo VH to JH rearrangement violating the 12/23 rule

The Journal of experimental medicine, 2005-02, Vol.201 (3), p.341-348

2005

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Recombinant ST2 boosts hepatic Th2 response in vivo

Journal of leukocyte biology, 2007-07, Vol.82 (1), p.124-132

2007

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PSGL-1 is a novel macrophage checkpoint in immuno-oncology

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e15090-e15090

2020

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V H replacement in primary immunoglobulin repertoire diversification

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5)

2015

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Abstract 5001: Quantitative systems pharmacology modeling and analysis provides biological insights into anti-PD-1 dosing and predicts optimal PD-1 x TIM-3 therapeutic properties for bispecifics and fixed dose combinations in immuno-oncology

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.5001-5001

2016

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Abstract 5613: Targeting VSIG4, a novel macrophage checkpoint, repolarizes suppressive macrophages which induces an inflammatory response in primary cell in vitro assays and fresh human tumor cultures, and inhibits tumor growth in in vivo murine tumor models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5613-5613

2022

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Abstract 5602: VTX-0811, a first-in-class PSGL-1 blocking monoclonal antibody, repolarizes tumor associated macrophages and induces inflammation in the tumor microenvironment, leading to suppression of tumor growth in pre-clinical studies

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5602-5602

2022

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In vivo delivery of lipidoid nanoparticles containing PD-L1 siRNA enhances NK and CD8+ T cell-mediated hepatic antiviral immunity (168.6)

The Journal of immunology (1950), 2012-05, Vol.188 (1_Supplement), p.168-168.6

2012

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VHreplacement in primary immunoglobulin repertoire diversification

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.E458-E466

2015

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V^sub H^ replacement in primary immunoglobulin repertoire diversification

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.E458

2015

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V sub( H) replacement in primary immunoglobulin repertoire diversification

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.E458-E458

2015

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1024 In Vivo Efficacy of C12-200 Lipid-Like SiRNA Carriers to Inhibit Hepatic Fibrosis

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-942-S-942

2012

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Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

The Journal of experimental medicine, 2003-05, Vol.197 (9), p.1165-1172

2003

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Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.10763-10764

2012

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Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements

The Journal of experimental medicine, 2003-05, Vol.197 (9), p.1165-1172

2003

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Therapeutic siRNA silencing in inflammatory monocytes

Nature biotechnology, 2011-10, Vol.29 (11), p.1005-1010

2011

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Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production

Therapeutic siRNA silencing in inflammatory monocytes in mice

Origins of tumor-associated macrophages and neutrophils

Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

VH replacement in primary immunoglobulin repertoire diversification

Loss of NFAT5 Results in Renal Atrophy and Lack of Tonicity-Responsive Gene Expression

Direct in vivo VH to JH rearrangement violating the 12/23 rule

Recombinant ST2 boosts hepatic Th2 response in vivo

PSGL-1 is a novel macrophage checkpoint in immuno-oncology

V H replacement in primary immunoglobulin repertoire diversification

Abstract 5001: Quantitative systems pharmacology modeling and analysis provides biological insights into anti-PD-1 dosing and predicts optimal PD-1 x TIM-3 therapeutic properties for bispecifics and fixed dose combinations in immuno-oncology

Abstract 5613: Targeting VSIG4, a novel macrophage checkpoint, repolarizes suppressive macrophages which induces an inflammatory response in primary cell in vitro assays and fresh human tumor cultures, and inhibits tumor growth in in vivo murine tumor models

Abstract 5602: VTX-0811, a first-in-class PSGL-1 blocking monoclonal antibody, repolarizes tumor associated macrophages and induces inflammation in the tumor microenvironment, leading to suppression of tumor growth in pre-clinical studies

In vivo delivery of lipidoid nanoparticles containing PD-L1 siRNA enhances NK and CD8+ T cell-mediated hepatic antiviral immunity (168.6)

VHreplacement in primary immunoglobulin repertoire diversification

V^sub H^ replacement in primary immunoglobulin repertoire diversification

V sub( H) replacement in primary immunoglobulin repertoire diversification

1024 In Vivo Efficacy of C12-200 Lipid-Like SiRNA Carriers to Inhibit Hepatic Fibrosis

Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements

Therapeutic siRNA silencing in inflammatory monocytes

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