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Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

Science (American Association for the Advancement of Science), 2013-10, Vol.342 (6157), p.447-453

2013

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inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.15064-15069

2008

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The Mucin Muc2 Limits Pathogen Burdens and Epithelial Barrier Dysfunction during Salmonella enterica Serovar Typhimurium Colitis

Infection and Immunity, 2013-10, Vol.81 (10), p.3672-3683

2013

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Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa

PLoS pathogens, 2010-05, Vol.6 (5), p.e1000902-e1000902

2010

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Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

The Journal of biological chemistry, 2006-05, Vol.281 (19), p.13548-13558

2006

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Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

Gastroenterology (New York, N.Y. 1943), 2010-05, Vol.138 (5), p.1763-1771.e5

2010

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Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis

PloS one, 2014-06, Vol.9 (6), p.e100217-e100217

2014

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Colorectal Cancer in Mice Genetically Deficient in the Mucin Muc2

Science (American Association for the Advancement of Science), 2002-03, Vol.295 (5560), p.1726-1729

2002

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Natural anti-intestinal goblet cell autoantibody production from marginal zone B cells

The Journal of immunology (1950), 2015-01, Vol.194 (2), p.606-614

2015

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Dietary Induction of Colonic Tumors in a Mouse Model of Sporadic Colon Cancer

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (19), p.7803-7810

2008

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Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis : Potential Role of Chronic Inflammation

Cancer research (Chicago, Ill.), 2008-09, Vol.68 (18), p.7313-7322

2008

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Importance and regulation of the colonic mucus barrier in a mouse model of colitis

American journal of physiology: Gastrointestinal and liver physiology, 2011-02, Vol.300 (2), p.G327-G333

2011

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Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation

Gastroenterology (New York, N.Y. 1943), 2001-03, Vol.120 (4), p.889-899

2001

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Methotrexate-induced mucositis in mucin 2-deficient mice

Journal of cellular physiology, 2007-01, Vol.210 (1), p.144-152

2007

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Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection

Gastroenterology (New York, N.Y. 1943), 2006-07, Vol.131 (1), p.117-129

2006

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Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions

Cancer biotherapy & radiopharmaceuticals, 2014-05, Vol.29 (4), p.153-161

2014

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Organization and Regulatory Aspects of the Human Intestinal Mucin Gene (MUC2) Locus

The Journal of biological chemistry, 1997-03, Vol.272 (12), p.7968-7976

1997

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Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation

Cancer research (Chicago, Ill.), 2001-04, Vol.61 (8), p.3465-3471

2001

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Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation

Oncogene, 2003-08, Vol.22 (32), p.4983-4992

2003

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Short Chain Fatty Acids and Colon Cancer

The Journal of nutrition, 2002-12, Vol.132 (12), p.3804S-3808S

2002

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Dietary Components Modify Gene Expression: Implications for Carcinogenesis

The Journal of nutrition, 2005-11, Vol.135 (11), p.2710-2714

2005

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Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells

Journal of cellular physiology, 2009-03, Vol.218 (3), p.638-642

2009

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Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice

Laboratory investigation, 2008-06, Vol.88 (6), p.634-642

2008

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Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention

Cancer research (Chicago, Ill.), 2002-11, Vol.62 (21), p.6006-6010

2002

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Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

The Mucin Muc2 Limits Pathogen Burdens and Epithelial Barrier Dysfunction during Salmonella enterica Serovar Typhimurium Colitis

Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa

Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

Colorectal Cancer in Mice Genetically Deficient in the Mucin Muc2

Natural anti-intestinal goblet cell autoantibody production from marginal zone B cells

Dietary Induction of Colonic Tumors in a Mouse Model of Sporadic Colon Cancer

Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis : Potential Role of Chronic Inflammation

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation

Methotrexate-induced mucositis in mucin 2-deficient mice

Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection

Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions

Organization and Regulatory Aspects of the Human Intestinal Mucin Gene (MUC2) Locus

Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation

Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation

Short Chain Fatty Acids and Colon Cancer

Dietary Components Modify Gene Expression: Implications for Carcinogenesis

Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells

Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice

Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention

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