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The CRISPR-Cas toolbox and gene editing technologies

Molecular cell, 2022-01, Vol.82 (2), p.333-347

2022

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Family Incivility and Cyberbullying Perpetration Among College Students: Negative Affect as a Mediator and Dispositional Mindfulness as a Moderator

Journal of interpersonal violence, 2022-12, Vol.37 (23-24), p.NP21826-NP21849

2022

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Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice

Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6437), p.292-295

2019

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Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion

Genome Biology, 2018-05, Vol.19 (1), p.59-59, Article 59

2018

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High-efficiency prime editing with optimized, paired pegRNAs in plants

Nature biotechnology, 2021-08, Vol.39 (8), p.923-927

2021

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Prime genome editing in rice and wheat

Nature biotechnology, 2020-05, Vol.38 (5), p.582-585

2020

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Genome-wide specificity of prime editors in plants

Nature biotechnology, 2021-10, Vol.39 (10), p.1292-1299

2021

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Rational modulation of coumarin-hemicyanine platform based on OH substitution for higher selective detection of hypochlorite

Chemical communications (Cambridge, England), 2020-01, Vol.56 (8), p.1219-1222

2020

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Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.776-788

2017

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Structural basis for activity regulation of MLL family methyltransferases

Nature (London), 2016-02, Vol.530 (7591), p.447-452

2016

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Studies of a Diazo Cyclopropanation Strategy for the Total Synthesis of (−)-Lundurine A

Chemistry : a European journal, 2015-09, Vol.21 (38), p.13284-13290

2015

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An unbiased method for evaluating the genome-wide specificity of base editors in rice

Nature protocols, 2021-01, Vol.16 (1), p.431-457

2021

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Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

Cancer cell, 2018-03, Vol.33 (3), p.368-385.e7

2018

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Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2017-10, Vol.139, p.48-59

2017

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Structural insights into NDH-1 mediated cyclic electron transfer

Nature communications, 2020-02, Vol.11 (1), p.888-888, Article 888

2020

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Overall survival prediction models for gynecological endometrioid adenocarcinoma with squamous differentiation (GE-ASqD) using machine-learning algorithms

Scientific reports, 2023-05, Vol.13 (1), p.8395-8395, Article 8395

2023

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Disease burden of stroke and its subtypes attributable to low dietary fiber in China, 1990–2019

Scientific reports, 2024-07, Vol.14 (1), p.15854-10, Article 15854

2024

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SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds

Genome Biology, 2020-06, Vol.21 (1), p.141-141, Article 141

2020

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All-in-one: Accurate quantification, on-site detection, and bioimaging of sulfite using a colorimetric and ratiometric fluorescent probe in vitro and in vivo

Journal of hazardous materials, 2022-02, Vol.424 (Pt B), p.127229-127229, Article 127229

2022

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Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease

European journal of medicinal chemistry, 2015-05, Vol.95, p.153-165

2015

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Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis

Journal of global health, 2018-12, Vol.8 (2), p.020503-020503

2018

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Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation

Bioorganic chemistry, 2018-12, Vol.81, p.512-528

2018

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Design, synthesis and biological evaluation of novel donepezil–coumarin hybrids as multi-target agents for the treatment of Alzheimer’s disease

Bioorganic & medicinal chemistry, 2016-04, Vol.24 (7), p.1528-1539

2016

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Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors

European journal of medicinal chemistry, 2017-06, Vol.133, p.184-196

2017

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Multifunctional coumarin derivatives: Monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.508-513

2015

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The CRISPR-Cas toolbox and gene editing technologies

Family Incivility and Cyberbullying Perpetration Among College Students: Negative Affect as a Mediator and Dispositional Mindfulness as a Moderator

Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice

Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion

High-efficiency prime editing with optimized, paired pegRNAs in plants

Prime genome editing in rice and wheat

Genome-wide specificity of prime editors in plants

Rational modulation of coumarin-hemicyanine platform based on OH substitution for higher selective detection of hypochlorite

Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease

Structural basis for activity regulation of MLL family methyltransferases

Studies of a Diazo Cyclopropanation Strategy for the Total Synthesis of (−)-Lundurine A

An unbiased method for evaluating the genome-wide specificity of base editors in rice

Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease

Structural insights into NDH-1 mediated cyclic electron transfer

Overall survival prediction models for gynecological endometrioid adenocarcinoma with squamous differentiation (GE-ASqD) using machine-learning algorithms

Disease burden of stroke and its subtypes attributable to low dietary fiber in China, 1990–2019

SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds

All-in-one: Accurate quantification, on-site detection, and bioimaging of sulfite using a colorimetric and ratiometric fluorescent probe in vitro and in vivo

Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease

Variations of dry eye disease prevalence by age, sex and geographic characteristics in China: a systematic review and meta-analysis

Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation

Design, synthesis and biological evaluation of novel donepezil–coumarin hybrids as multi-target agents for the treatment of Alzheimer’s disease

Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors

Multifunctional coumarin derivatives: Monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer’s disease

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