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Genetic correlations of polygenic disease traits: from theory to practice

Nature reviews. Genetics, 2019-10, Vol.20 (10), p.567-581

2019

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All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

PLoS genetics, 2013-04, Vol.9 (4), p.e1003449-e1003449

2013

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Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

American journal of human genetics, 2013-02, Vol.92 (2), p.197-209

2013

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Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

PLoS genetics, 2013-04, Vol.9 (4), p.e1003455

2013

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Human Disease Variation in the Light of Population Genomics

Cell, 2019-03, Vol.177 (1), p.115-131

2019

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New statistical approaches exploit the polygenic architecture of schizophrenia — implications for the underlying neurobiology

Current opinion in neurobiology, 2016-02, Vol.36, p.89-98

2016

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Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

Nature communications, 2021-11, Vol.12 (1), p.6617-12, Article 6617

2021

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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Nature communications, 2018-12, Vol.9 (1), p.5296-7, Article 5296

2018

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Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Translational psychiatry, 2023-05, Vol.13 (1), p.174-174, Article 174

2023

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Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms

PloS one, 2015-04, Vol.10 (4), p.e0123057-e0123057

2015

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Probing the Association between Early Evolutionary Markers and Schizophrenia

PloS one, 2017-01, Vol.12 (1), p.e0169227-e0169227

2017

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Genetic risks and clinical rewards

Nature genetics, 2018-09, Vol.50 (9), p.1210-1211

2018

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Genetic Implication of a Novel Thiamine Transporter in Human Hypertension

Journal of the American College of Cardiology, 2014-04, Vol.63 (15), p.1542-1555

2014

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An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

PLoS genetics, 2015-12, Vol.11 (12), p.e1005717-e1005717

2015

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Cross-trait assortative mating is widespread and inflates genetic correlation estimates

Science (American Association for the Advancement of Science), 2022-11, Vol.378 (6621), p.754-761

2022

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Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments

Biological psychiatry (1969), 2024-06, Vol.95 (12), p.1110-1121

2024

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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

Communications biology, 2023-01, Vol.6 (1), p.101-101, Article 101

2023

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Indirect paths from genetics to education

Nature genetics, 2022-04, Vol.54 (4), p.372-373

2022

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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder

Nature genetics, 2023-12, Vol.55 (12), p.2082-2093

2023

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A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1

2022

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Genetic Markers of Human Evolution Are Enriched in Schizophrenia

Biological psychiatry (1969), 2016-08, Vol.80 (4), p.284-292

2016

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Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

JAMA psychiatry (Chicago, Ill.), 2021-04, Vol.78 (4), p.387

2021

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Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD

The American journal of psychiatry, 2021-09, Vol.178 (9), p.854-864

2021

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Genetic correlations of polygenic disease traits: from theory to practice

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

Human Disease Variation in the Light of Population Genomics

New statistical approaches exploit the polygenic architecture of schizophrenia — implications for the underlying neurobiology

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms

Probing the Association between Early Evolutionary Markers and Schizophrenia

Genetic risks and clinical rewards

Genetic Implication of a Novel Thiamine Transporter in Human Hypertension

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

Cross-trait assortative mating is widespread and inflates genetic correlation estimates

Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments

Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

Indirect paths from genetics to education

Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Genetic Markers of Human Evolution Are Enriched in Schizophrenia

Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD

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