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Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

Journal of controlled release, 2012-12, Vol.164 (3), p.364-369

2012

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Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats

Journal of drug targeting, 2014-06, Vol.22 (5), p.460-467

2014

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Liposome technologies and drug delivery to the CNS

Drug discovery today. Technologies, 2016-06, Vol.20, p.53-58

Rip, Jaap

2016

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Targeted blood-to-brain drug delivery --10 key development criteria

Current pharmaceutical biotechnology, 2012-09, Vol.13 (12), p.2328

2012

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Gene therapy for lipoprotein lipase deficiency : Working toward clinical application

Human gene therapy, 2005-11, Vol.16 (11), p.1276-1286

2005

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In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

Pharmaceutical research, 2016-01, Vol.33 (1), p.177-185

2016

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Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

Journal of controlled release, 2015-04, Vol.203, p.40-50

2015

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Enhanced Brain Delivery of the Opioid Peptide DAMGO in Glutathione PEGylated Liposomes: A Microdialysis Study

Molecular pharmaceutics, 2013-05, Vol.10 (5), p.1533-1541

2013

Volltextzugriff (PDF)

The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2606-2613

2017

Volltextzugriff (PDF)

In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine

Molecular pharmaceutics, 2018-12, Vol.15 (12), p.5493-5500

2018

Volltextzugriff (PDF)

Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo

Drug discovery today. Technologies, 2016-06, Vol.20, p.59-69

2016

Volltextzugriff (PDF)

Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation

Investigative ophthalmology & visual science, 2014-04, Vol.55 (4), p.2788-2794

2014

Volltextzugriff (PDF)

A poly(amidoamine)-based polymeric nanoparticle platform for efficient in vivo delivery of mRNA

Biomaterials Advances, 2024-01, Vol.156, p.213713-213713, Article 213713

2024

Volltextzugriff (PDF)

Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation

Arteriosclerosis, thrombosis, and vascular biology, 2006-06, Vol.26 (6), p.1236

2006

Volltextzugriff (PDF)

Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation

Human gene therapy, 2006-05, Vol.17 (5), p.487

2006

Volltextzugriff (PDF)

Efficient CRM197-mediated drug targeting to monocytes

Journal of controlled release, 2012-02, Vol.158 (1), p.139-147

2012

Volltextzugriff (PDF)

Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation

Arteriosclerosis, thrombosis, and vascular biology, 2005-10, Vol.25 (10), p.2143

2005

Volltextzugriff (PDF)

Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation

Human gene therapy, 2004-09, Vol.15 (9), p.906-919

2004

Volltextzugriff (PDF)

Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study

Arteriosclerosis, thrombosis, and vascular biology, 2006-03, Vol.26 (3), p.637

2006

Volltextzugriff (PDF)

Adeno-associated virus LPL(S447X) gene therapy in LDL receptor knockout mice

Atherosclerosis, 2007-09, Vol.194 (1), p.55-61

2007

Volltextzugriff (PDF)

AAV1-LPL(S447X) gene therapy reduces hypertriglyceridemia in apoE2 knock in mice

Biochimica et biophysica acta, 2006-10, Vol.1761 (10), p.1163

2006

Volltextzugriff (PDF)

Gene therapy with lipoprotein lipase variant S447X

Arteriosclerosis, thrombosis, and vascular biology, 2006-03, Vol.26 (3), p.e25; author reply e25

Hegele, Robert A

2006

Volltextzugriff (PDF)

Carriers of the frequent lipoprotein lipase S447X variant exhibit enhanced postprandial apoprotein B-48 clearance

Metabolism, clinical and experimental, 2005-11, Vol.54 (11), p.1499-1503

2005

Volltextzugriff (PDF)

Enhanced conversion of triglyceride-rich lipoproteins and increased low-density lipoprotein removal in LPLS447X carriers

Arteriosclerosis, thrombosis, and vascular biology, 2005-11, Vol.25 (11), p.2410

2005

Volltextzugriff (PDF)

Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes

Atherosclerosis, 2007-10, Vol.194 (2), p.446-451

2007

Volltextzugriff (PDF)

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Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats

Liposome technologies and drug delivery to the CNS

Targeted blood-to-brain drug delivery --10 key development criteria

Gene therapy for lipoprotein lipase deficiency : Working toward clinical application

In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

Enhanced Brain Delivery of the Opioid Peptide DAMGO in Glutathione PEGylated Liposomes: A Microdialysis Study

The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study

In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine

Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo

Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation

A poly(amidoamine)-based polymeric nanoparticle platform for efficient in vivo delivery of mRNA

Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation

Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation

Efficient CRM197-mediated drug targeting to monocytes

Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation

Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation

Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study

Adeno-associated virus LPL(S447X) gene therapy in LDL receptor knockout mice

AAV1-LPL(S447X) gene therapy reduces hypertriglyceridemia in apoE2 knock in mice

Gene therapy with lipoprotein lipase variant S447X

Carriers of the frequent lipoprotein lipase S447X variant exhibit enhanced postprandial apoprotein B-48 clearance

Enhanced conversion of triglyceride-rich lipoproteins and increased low-density lipoprotein removal in LPLS447X carriers

Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes

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