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ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity

Biochemical Society transactions, 2024-06, Vol.52 (3), p.1293-1304

Paoletti, Francesca

2024

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Small Endogenous Ligands Modulation of Nerve Growth Factor Bioactivity: A Structural Biology Overview

Cells (Basel, Switzerland), 2021-12, Vol.10 (12), p.3462

2021

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Intranasal delivery of therapeutic proteins for neurological diseases

Expert opinion on drug delivery, 2011-10, Vol.8 (10), p.1277-1296

2011

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A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor

Biochimica et biophysica acta, 2015-03, Vol.1854 (3), p.187-197

2015

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Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications

PloS one, 2015-09, Vol.10 (9), p.e0136425-e0136425

2015

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The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?

Biophysical journal, 2015-02, Vol.108 (3), p.687-697

2015

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RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex

PloS one, 2012-04, Vol.7 (4), p.e35034-e35034

2012

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NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling

PloS one, 2011-06, Vol.6 (6), p.e20839-e20839

2011

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Conformational plasticity of proNGF

PloS one, 2011-07, Vol.6 (7), p.e22615-e22615

2011

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Intrinsic structural disorder of mouse proNGF

Proteins, structure, function, and bioinformatics, 2009-06, Vol.75 (4), p.990-1009

2009

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Nerve growth factor regulates axial rotation during early stages of chick embryo development

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (6), p.2009-2014

2012

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Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment

Archives of biochemistry and biophysics, 2012-06, Vol.522 (1), p.26-36

2012

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Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg 2

Protein science, 2023-02, Vol.32 (2), p.e4563

2023

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Severe rituximab‐induced pneumonitis in an immunocompromised child with acquired thrombotic thrombocytopenic purpura

Pediatric blood & cancer, 2022-02, Vol.69 (2), p.e29375-n/a

2022

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The Structure of the Pro-domain of Mouse proNGF in Contact with the NGF Domain

Structure (London), 2019-01, Vol.27 (1), p.78-89.e3

2019

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Reduced Klebsiella pneumoniae carbapenemase–producing K. pneumoniae (KPC-KP) colonization in a hematological-emergency setting during the coronavirus disease 2019 (COVID-19) pandemic

Infection control and hospital epidemiology, 2022-12, Vol.43 (12), p.1963-1965

2022

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Towards non invasive nerve growth factor therapies for Alzheimer's disease

Journal of Alzheimer's disease, 2008-10, Vol.15 (2), p.255-283

2008

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Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

PloS one, 2012, Vol.7 (5), p.e37555

2012

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Dynamics of HIV DNA and residual viremia in patients treated with a raltegravir-containing regimen

Journal of acquired immune deficiency syndromes (1999), 2015-02, Vol.68 (2), p.e18-e20

2015

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In vitro receptor binding properties of a “painless” NGF mutein, linked to hereditary sensory autonomic neuropathy type V

Biochemical and biophysical research communications, 2010-01, Vol.391 (1), p.824-829

2010

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proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces

BMC neuroscience, 2014-04, Vol.15 (1), p.48-48, Article 48

2014

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Novel fluorescent cycloheximide derivatives for the imaging of protein synthesis

Biochemical and biophysical research communications, 2010-05, Vol.396 (2), p.258-264

2010

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Mutational resistance pattern of HIV type 1 in CD14+ monocytes, CD4+ T cells, and plasma from treated patients

AIDS research and human retroviruses, 2010-06, Vol.26 (6), p.625-634

2010

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Safety and efficacy of treatment switch to raltegravir plus tenofovir/emtricitabine or abacavir/lamivudine in patients with optimal virological control: 48-week results from a randomized pilot study (Raltegravir Switch for Toxicity or Adverse Events, RASTA Study)

Scandinavian journal of infectious diseases, 2014-01, Vol.46 (1), p.34-45

2014

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Cerebrospinal fluid interleukin 8 in children with purulent bacterial and tuberculous meningitis

The Pediatric infectious disease journal, 1994-11, Vol.13 (11), p.1008-1009

1994

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ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity

Small Endogenous Ligands Modulation of Nerve Growth Factor Bioactivity: A Structural Biology Overview

Intranasal delivery of therapeutic proteins for neurological diseases

A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications

The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?

RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex

NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling

Conformational plasticity of proNGF

Intrinsic structural disorder of mouse proNGF

Nerve growth factor regulates axial rotation during early stages of chick embryo development

Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment

Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg 2

Severe rituximab‐induced pneumonitis in an immunocompromised child with acquired thrombotic thrombocytopenic purpura

The Structure of the Pro-domain of Mouse proNGF in Contact with the NGF Domain

Reduced Klebsiella pneumoniae carbapenemase–producing K. pneumoniae (KPC-KP) colonization in a hematological-emergency setting during the coronavirus disease 2019 (COVID-19) pandemic

Towards non invasive nerve growth factor therapies for Alzheimer's disease

Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

Dynamics of HIV DNA and residual viremia in patients treated with a raltegravir-containing regimen

In vitro receptor binding properties of a “painless” NGF mutein, linked to hereditary sensory autonomic neuropathy type V

proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces

Novel fluorescent cycloheximide derivatives for the imaging of protein synthesis

Mutational resistance pattern of HIV type 1 in CD14+ monocytes, CD4+ T cells, and plasma from treated patients

Safety and efficacy of treatment switch to raltegravir plus tenofovir/emtricitabine or abacavir/lamivudine in patients with optimal virological control: 48-week results from a randomized pilot study (Raltegravir Switch for Toxicity or Adverse Events, RASTA Study)

Cerebrospinal fluid interleukin 8 in children with purulent bacterial and tuberculous meningitis

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