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Applying Biopharmaceutical Classification System (BCS) Criteria to Predict Oral Absorption of Drugs in Dogs: Challenges and Pitfalls

The AAPS journal, 2015-07, Vol.17 (4), p.948-964

2015

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Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.2795-2805

2012

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Impact of bovine respiratory disease on the pharmacokinetics of danofloxacin and tulathromycin in different ages of calves

PloS one, 2019-06, Vol.14 (6), p.e0218864

2019

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A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

Journal of clinical pharmacology, 2002-06, Vol.42 (6), p.620-643

2002

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Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics

Drug metabolism reviews, 2013-05, Vol.45 (2), p.218-230

2013

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Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

Cells (Basel, Switzerland), 2023-04, Vol.12 (9), p.1269

2023

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Evaluating the solubility of compounds intended for intramammary infusion based upon tests conducted across a range of milk matrices

PloS one, 2023-07, Vol.18 (7), p.e0288780-e0288780

2023

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Individualized Patient Care Through Model-Informed Precision Dosing: Reflections on Training Future Practitioners

The AAPS journal, 2022-11, Vol.24 (6), p.117, Article 117

2022

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Factors Influencing the Use and Interpretation of Animal Models in the Development of Parenteral Drug Delivery Systems

The AAPS journal, 2011-12, Vol.13 (4), p.632-649

Martinez, Marilyn N.

2011

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Using simulations to explore the potential effect of disease and inflammation on the frequency of violative flunixin residues in cattle

Journal of veterinary pharmacology and therapeutics, 2023-03, Vol.46 (2), p.91-102

2023

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When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

Drug metabolism and disposition, 2016-12, Vol.44 (12), p.1934-1939

2016

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The Use of Systemically Absorbed Drugs to Explore An In Vitro Bioequivalence Approach For Comparing Non-Systemically Absorbed Active Pharmaceutical Ingredients in Drug Products For Use in Dogs

Pharmaceutical research, 2024-09, Vol.41 (9), p.1797-1809

2024

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A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development

The AAPS journal, 2022-05, Vol.24 (3), p.61-61, Article 61

2022

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A Critical Overview of the Biological Effects of Excipients (Part I): Impact on Gastrointestinal Absorption

The AAPS journal, 2022-05, Vol.24 (3), p.60-60, Article 60

2022

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Development and Validation of Discriminatory In-vitro Release Method for Intramammary Drug Product

Pharmaceutical research, 2024, Vol.41 (1), p.129-139

2024

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Proposed method for estimating clinical cut-off (COCL) values: An attempt to address challenges encountered when setting clinical breakpoints for veterinary antimicrobial agents

The veterinary journal (1997), 2017-10, Vol.228, p.33-37

2017

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Canine gastrointestinal physiology: Breeds variations that can influence drug absorption

European journal of pharmaceutics and biopharmaceutics, 2015-11, Vol.97 (Pt A), p.192-203

2015

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The publication of studies involving the use of human critically important antimicrobial agents in veterinary species

Journal of veterinary pharmacology and therapeutics, 2021-11, Vol.44 (6), p.986-989

2021

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Examining the Use of a Mechanistic Model to Generate an In Vivo/In Vitro Correlation: Journey Through a Thought Process

The AAPS journal, 2016-09, Vol.18 (5), p.1144-1158

2016

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Canine Intestinal Organoids in a Dual-Chamber Permeable Support System

Journal of visualized experiments, 2022-03 (181)

2022

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Expert Discussion of the Role of Rate Constant Versus Clearance Approaches to Define Drug Pharmacokinetics: Theoretical and Clinical Considerations

The AAPS journal, 2020-01, Vol.22 (2), p.25, Article 25

2020

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Questions associated with the development of novel drugs intended for the treatment of bacterial infections in veterinary species

The veterinary journal (1997), 2019-06, Vol.248, p.79-85

2019

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Demonstrating Comparative In Vitro Bioequivalence for Animal Drug Products Through Chemistry and Manufacturing Controls and Physicochemical Characterization: A Proposal

The AAPS journal, 2015-03, Vol.17 (2), p.307-312

2015

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Breakout session summary from AAPS/CRS joint workshop on critical variables in the in vitro and in vivo performance of parenteral sustained release products

Journal of controlled release, 2010-02, Vol.142 (1), p.2-7

2010

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The Biopharmaceutics Risk Assessment Roadmap for Optimizing Clinical Drug Product Performance

Journal of pharmaceutical sciences, 2014-11, Vol.103 (11), p.3377-3397

2014

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Applying Biopharmaceutical Classification System (BCS) Criteria to Predict Oral Absorption of Drugs in Dogs: Challenges and Pitfalls

Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

Impact of bovine respiratory disease on the pharmacokinetics of danofloxacin and tulathromycin in different ages of calves

A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics

Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

Evaluating the solubility of compounds intended for intramammary infusion based upon tests conducted across a range of milk matrices

Individualized Patient Care Through Model-Informed Precision Dosing: Reflections on Training Future Practitioners

Factors Influencing the Use and Interpretation of Animal Models in the Development of Parenteral Drug Delivery Systems

Using simulations to explore the potential effect of disease and inflammation on the frequency of violative flunixin residues in cattle

When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

The Use of Systemically Absorbed Drugs to Explore An In Vitro Bioequivalence Approach For Comparing Non-Systemically Absorbed Active Pharmaceutical Ingredients in Drug Products For Use in Dogs

A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development

A Critical Overview of the Biological Effects of Excipients (Part I): Impact on Gastrointestinal Absorption

Development and Validation of Discriminatory In-vitro Release Method for Intramammary Drug Product

Proposed method for estimating clinical cut-off (COCL) values: An attempt to address challenges encountered when setting clinical breakpoints for veterinary antimicrobial agents

Canine gastrointestinal physiology: Breeds variations that can influence drug absorption

The publication of studies involving the use of human critically important antimicrobial agents in veterinary species

Examining the Use of a Mechanistic Model to Generate an In Vivo/In Vitro Correlation: Journey Through a Thought Process

Canine Intestinal Organoids in a Dual-Chamber Permeable Support System

Expert Discussion of the Role of Rate Constant Versus Clearance Approaches to Define Drug Pharmacokinetics: Theoretical and Clinical Considerations

Questions associated with the development of novel drugs intended for the treatment of bacterial infections in veterinary species

Demonstrating Comparative In Vitro Bioequivalence for Animal Drug Products Through Chemistry and Manufacturing Controls and Physicochemical Characterization: A Proposal

Breakout session summary from AAPS/CRS joint workshop on critical variables in the in vitro and in vivo performance of parenteral sustained release products

The Biopharmaceutics Risk Assessment Roadmap for Optimizing Clinical Drug Product Performance

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