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The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation

Molecular medicine (Cambridge, Mass.), 2020-06, Vol.26 (1), p.63-63, Article 63

2020

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Carbon monoxide provides protection against hyperoxic lung injury

American journal of physiology. Lung cellular and molecular physiology, 1999-04, Vol.276 (4), p.688-L694

1999

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From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19?

Journal of immunotoxicology, 2021-01, Vol.18 (1), p.23-29

2021

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HMGB-1 as a therapeutic target for infectious and inflammatory disorders

Shock (Augusta, Ga.), 2006, Vol.25 (1), p.4-11

2006

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2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function

Molecular medicine (Cambridge, Mass.), 2021-07, Vol.27 (1), p.79-79, Article 79

2021

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Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

The Journal of clinical investigation, 1999-04, Vol.103 (7), p.1047-1054

1999

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Hyperoxia sensing: From molecular mechanisms to significance in disease

Journal of immunotoxicology, 2010-12, Vol.7 (4), p.239-254

2010

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Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

Redox biology, 2014-01, Vol.2 (C), p.314-322

2014

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The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

Molecular medicine (Cambridge, Mass.), 2014-06, Vol.20 (1), p.238-247

2014

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Interleukin-6-Induced Protection in Hyperoxic Acute Lung Injury

American journal of respiratory cell and molecular biology, 2000-05, Vol.22 (5), p.535-542

2000

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Signal Transduction Pathways in Hyperoxia-Induced Lung Cell Death

Molecular Genetics and Metabolism, 2000-09, Vol.71 (1-2), p.359-370

2000

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Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19

Free radical biology & medicine, 2022-09, Vol.190, p.247-263

2022

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MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells

Free radical biology & medicine, 2003-10, Vol.35 (8), p.978-993

2003

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Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia

Free radical biology & medicine, 2007-05, Vol.42 (9), p.1338-1349

2007

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Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells

American journal of physiology. Lung cellular and molecular physiology, 1999-09, Vol.277 (3), p.589-L595

1999

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Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis

American journal of physiology. Lung cellular and molecular physiology, 2005-10, Vol.289 (4), p.L583-L590

2005

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Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (24), p.5299-5308

2015

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Hyperoxia Inhibits Oxidant-induced Apoptosis in Lung Epithelial Cells

The Journal of biological chemistry, 2001-01, Vol.276 (1), p.569-575

2001

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Introduction to serial reviews on redox signaling in immune function and cellular responses in lung injury and diseases

Free radical biology & medicine, 2006-07, Vol.41 (1), p.1-3

Mantell, Lin L.

2006

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GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation

Redox biology, 2023-04, Vol.60, p.102614-102614, Article 102614

2023

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Interleukin-11 and Interleukin-6 Protect Cultured Human Endothelial Cells from H2O2-Induced Cell Death

American journal of respiratory cell and molecular biology, 2003-10, Vol.29 (4), p.513

2003

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Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis

Molecular medicine (Cambridge, Mass.), 2012-05, Vol.18 (3), p.477-485

2012

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High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice

American journal of respiratory cell and molecular biology, 2013-03, Vol.48 (3), p.280-287

2013

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Telomerase activity in germline and embryonic cells of Xenopus

The EMBO journal, 1994-07, Vol.13 (13), p.3211-3217

1994

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Overexpression of Manganese Superoxide Dismutase Protects Lung Epithelial Cells against Oxidant Injury

American journal of respiratory cell and molecular biology, 2001-04, Vol.24 (4), p.436-441

2001

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The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation

Carbon monoxide provides protection against hyperoxic lung injury

From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19?

HMGB-1 as a therapeutic target for infectious and inflammatory disorders

2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function

Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

Hyperoxia sensing: From molecular mechanisms to significance in disease

Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

Interleukin-6-Induced Protection in Hyperoxic Acute Lung Injury

Signal Transduction Pathways in Hyperoxia-Induced Lung Cell Death

Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19

MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells

Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia

Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells

Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis

Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications

Hyperoxia Inhibits Oxidant-induced Apoptosis in Lung Epithelial Cells

Introduction to serial reviews on redox signaling in immune function and cellular responses in lung injury and diseases

GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation

Interleukin-11 and Interleukin-6 Protect Cultured Human Endothelial Cells from H2O2-Induced Cell Death

Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis

High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice

Telomerase activity in germline and embryonic cells of Xenopus

Overexpression of Manganese Superoxide Dismutase Protects Lung Epithelial Cells against Oxidant Injury

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