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Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-02, Vol.368 (1612), p.20120476

2013

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Research paradigms in medical education research

Medical education, 2010-04, Vol.44 (4), p.358-366

2010

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A cloacal opening in a non-avian dinosaur

Current biology, 2021-02, Vol.31 (4), p.R182-R183

2021

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Intromittent Organ Morphology and Biomechanics: Defining the Physical Challenges of Copulation

Integrative and comparative biology, 2016-10, Vol.56 (4), p.705-714

Kelly, Diane A.

2016

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Azole fungicides – understanding resistance mechanisms in agricultural fungal pathogens

Pest management science, 2015-08, Vol.71 (8), p.1054-1058

2015

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Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens

Antimicrobial Agents and Chemotherapy, 2013-03, Vol.57 (3), p.1352-1360

2013

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Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids

PloS one, 2022-03, Vol.17 (3), p.e0265227

2022

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In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection

Antimicrobial agents and chemotherapy, 2017-05, Vol.61 (5), p.e02280-16

2017

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Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

Antimicrobial Agents and Chemotherapy, 2012-08, Vol.56 (8), p.4223-4232

2012

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Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola

PloS one, 2011-06, Vol.6 (6), p.e20973-e20973

2011

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Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

Antimicrobial Agents and Chemotherapy, 2010-11, Vol.54 (11), p.4527-4533

2010

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A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

Antimicrobial Agents and Chemotherapy, 2010-09, Vol.54 (9), p.3578-3583

2010

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Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance

Molecular biology and evolution, 2014-07, Vol.31 (7), p.1793-1802

2014

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Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2

Antimicrobial Agents and Chemotherapy, 2012-12, Vol.56 (12), p.6417-6421

2012

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Genital interactions during simulated copulation among marine mammals

Proceedings of the Royal Society. B, Biological sciences, 2017-10, Vol.284 (1864), p.20171265-20171265

Royal Society (Great Britain), 2017

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The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions

Antimicrobial agents and chemotherapy, 2019-05, Vol.63 (5)

2019

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Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-02, Vol.1864 (2), p.191-211

2019

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The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4530-4538

2016

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Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase

Applied and Environmental Microbiology, 2013-03, Vol.79 (5), p.1639-1645

2013

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Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-α Demethylase (CYP51) Isoenzymes A and B

Antimicrobial Agents and Chemotherapy, 2010-10, Vol.54 (10), p.4225-4234

2010

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Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)

Antimicrobial Agents and Chemotherapy, 2010-10, Vol.54 (10), p.4235-4245

2010

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Morphological Characteristics Regulating Phallic Glans Engorgement in the American Alligator

Integrative and comparative biology, 2016-10, Vol.56 (4), p.657-668

2016

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Flux, questions, exclusion and compassion: collective learning in secondary care

Medical education, 2013-12, Vol.47 (12), p.1197-1208

2013

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Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans

ChemMedChem, 2020-07, Vol.15 (14), p.1294-1309

2020

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Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51)

Antimicrobial agents and chemotherapy, 2015-08, Vol.59 (8), p.4707-4713

2015

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Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?

Research paradigms in medical education research

A cloacal opening in a non-avian dinosaur

Intromittent Organ Morphology and Biomechanics: Defining the Physical Challenges of Copulation

Azole fungicides – understanding resistance mechanisms in agricultural fungal pathogens

Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens

Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance

Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2

Genital interactions during simulated copulation among marine mammals

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme

Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase

Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-α Demethylase (CYP51) Isoenzymes A and B

Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)

Morphological Characteristics Regulating Phallic Glans Engorgement in the American Alligator

Flux, questions, exclusion and compassion: collective learning in secondary care

Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans

Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51)

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