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Multidrug Efflux Pumps of Gram-Positive Bacteria

Drug resistance updates, 2016-07, Vol.27, p.1-13

2016

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A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition

PloS one, 2015-05, Vol.10 (5), p.e0124814-e0124814

2015

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Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2010-12, Vol.54 (12), p.5070-5073

2010

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Antimicrobial Salvage Therapy for Persistent Staphylococcal Bacteremia Using Daptomycin Plus Ceftaroline

Clinical therapeutics, 2014-10, Vol.36 (10), p.1317-1333

2014

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Evaluation of Ceftaroline Activity against Heteroresistant Vancomycin-Intermediate Staphylococcus aureus and Vancomycin-Intermediate Methicillin-Resistant S. aureus Strains in an In Vitro Pharmacokinetic/Pharmacodynamic Model: Exploring the “Seesaw Effect”

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2664-2668

2013

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Multidrug Resistance in Staphylococcus aureus Due to Overexpression of a Novel Multidrug and Toxin Extrusion (MATE) Transport Protein

Antimicrobial Agents and Chemotherapy, 2005-05, Vol.49 (5), p.1857-1864

2005

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Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR

Nucleic acids research, 2014-02, Vol.42 (4), p.2774-2788

2014

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Efflux-Related Resistance to Norfloxacin, Dyes, and Biocides in Bloodstream Isolates of Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3235-3239

2007

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Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus

International journal of antimicrobial agents, 2012-09, Vol.40 (3), p.204-209

2012

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Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes

Current drug metabolism, 2021-01, Vol.22 (2), p.114-122

2021

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Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana

Phytochemistry (Oxford), 2007, Vol.68 (2), p.210-217

2007

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Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump

Journal of Bacteriology, 2013-02, Vol.195 (3), p.523-533

2013

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Polyacylated Oligosaccharides from Medicinal Mexican Morning Glory Species as Antibacterials and Inhibitors of Multidrug Resistance in Staphylococcus aureus

Journal of natural products (Washington, D.C.), 2006-03, Vol.69 (3), p.406-409

2006

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The Phenolic Diterpene Totarol Inhibits Multidrug Efflux Pump Activity in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2007-12, Vol.51 (12), p.4480-4483

2007

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Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2003-02, Vol.47 (2), p.719-726

2003

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Daptomycin Activity against Staphylococcus aureus following Vancomycin Exposure in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations

Antimicrobial Agents and Chemotherapy, 2008-03, Vol.52 (3), p.831-836

2008

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Functional Consequences of Substitution Mutations in MepR, a Repressor of the Staphylococcus aureus mepA Multidrug Efflux Pump Gene

Journal of Bacteriology, 2013-08, Vol.195 (16), p.3651-3662

2013

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Community- and health care-associated methicillin-resistant Staphylococcus aureus : a comparison of molecular epidemiology and antimicrobial activities of various agents

Diagnostic microbiology and infectious disease, 2007-05, Vol.58 (1), p.41-47

2007

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MepR, a Repressor of the Staphylococcus aureus MATE Family Multidrug Efflux Pump MepA, Is a Substrate-Responsive Regulatory Protein

Antimicrobial Agents and Chemotherapy, 2006-04, Vol.50 (4), p.1276-1281

2006

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Characteristics of patients with healthcare-associated infection due to SCCmec type IV methicillin-resistant Staphylococcus aureus

Infection control and hospital epidemiology, 2006-10, Vol.27 (10), p.1025

2006

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Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of the S. aureus NorA Efflux Pump

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5722-5736

2011

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Effect of Promoter Region Mutations and mgrA Overexpression on Transcription of norA, Which Encodes a Staphylococcus aureus Multidrug Efflux Transporter

Antimicrobial Agents and Chemotherapy, 2005-01, Vol.49 (1), p.161-169

2005

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Mechanisms of daptomycin resistance in Staphylococcus aureus

International journal of antimicrobial agents, 2006-10, Vol.28 (4), p.280-287

2006

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Inhibition of drug efflux pumps in Staphylococcus aureus: current status of potentiating existing antibiotics

Future microbiology, 2013-04, Vol.8 (4), p.491-507

2013

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Characterizing Vancomycin-Resistant Enterococcus Strains with Various Mechanisms of Daptomycin Resistance Developed in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4748-4754

2011

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Multidrug Efflux Pumps of Gram-Positive Bacteria

A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition

Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus

Antimicrobial Salvage Therapy for Persistent Staphylococcal Bacteremia Using Daptomycin Plus Ceftaroline

Evaluation of Ceftaroline Activity against Heteroresistant Vancomycin-Intermediate Staphylococcus aureus and Vancomycin-Intermediate Methicillin-Resistant S. aureus Strains in an In Vitro Pharmacokinetic/Pharmacodynamic Model: Exploring the “Seesaw Effect”

Multidrug Resistance in Staphylococcus aureus Due to Overexpression of a Novel Multidrug and Toxin Extrusion (MATE) Transport Protein

Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR

Efflux-Related Resistance to Norfloxacin, Dyes, and Biocides in Bloodstream Isolates of Staphylococcus aureus

Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus

Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes

Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana

Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump

Polyacylated Oligosaccharides from Medicinal Mexican Morning Glory Species as Antibacterials and Inhibitors of Multidrug Resistance in Staphylococcus aureus

The Phenolic Diterpene Totarol Inhibits Multidrug Efflux Pump Activity in Staphylococcus aureus

Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in Staphylococcus aureus

Daptomycin Activity against Staphylococcus aureus following Vancomycin Exposure in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations

Functional Consequences of Substitution Mutations in MepR, a Repressor of the Staphylococcus aureus mepA Multidrug Efflux Pump Gene

Community- and health care-associated methicillin-resistant Staphylococcus aureus : a comparison of molecular epidemiology and antimicrobial activities of various agents

MepR, a Repressor of the Staphylococcus aureus MATE Family Multidrug Efflux Pump MepA, Is a Substrate-Responsive Regulatory Protein

Characteristics of patients with healthcare-associated infection due to SCCmec type IV methicillin-resistant Staphylococcus aureus

Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of the S. aureus NorA Efflux Pump

Effect of Promoter Region Mutations and mgrA Overexpression on Transcription of norA, Which Encodes a Staphylococcus aureus Multidrug Efflux Transporter

Mechanisms of daptomycin resistance in Staphylococcus aureus

Inhibition of drug efflux pumps in Staphylococcus aureus: current status of potentiating existing antibiotics

Characterizing Vancomycin-Resistant Enterococcus Strains with Various Mechanisms of Daptomycin Resistance Developed in an In Vitro Pharmacokinetic/Pharmacodynamic Model

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