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Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

Cell research, 2008, Vol.18 (1), p.27-47

2008

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Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes

Nature communications, 2016-10, Vol.7 (1), p.13049-13049, Article 13049

2016

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The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis

PLoS genetics, 2015-01, Vol.11 (1), p.e1004749

2015

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Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3

PLoS genetics, 2015-01, Vol.11 (1), p.e1004834

2015

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Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells

The Journal of biological chemistry, 2020-08, Vol.295 (32), p.11082-11098

2020

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Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription

eLife, 2019-04, Vol.8

2019

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Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.49679-49684

2003

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Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation

The Journal of biological chemistry, 2015-10, Vol.290 (41), p.24636-24648

2015

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Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine

The Journal of biological chemistry, 2012-06, Vol.287 (25), p.20769-20773

2012

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Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6006-6016

2011

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Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.E3090-E3099

2013

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MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

Cell reports (Cambridge), 2014-07, Vol.8 (1), p.177-189

2014

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The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection

Nature communications, 2023-12, Vol.14 (1), p.8169-8169, Article 8169

2023

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Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

DNA repair, 2013-01, Vol.12 (1), p.18-26

2013

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Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue

Cell reports (Cambridge), 2017-08, Vol.20 (9), p.1995-1996

2017

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Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

Redox biology, 2018-09, Vol.18, p.43-53

2018

Volltextzugriff (PDF)

Functions of disordered regions in mammalian early base excision repair proteins

Cellular and molecular life sciences : CMLS, 2010-11, Vol.67 (21), p.3573-3587

2010

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Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome

The Journal of biological chemistry, 2012, Vol.287 (4), p.2819-2829

2012

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Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

DNA repair, 2013-10, Vol.12 (10), p.856-863

2013

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Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions

Journal of innate immunity, 2022, Vol.14 (6), p.593-614

2022

Volltextzugriff (PDF)

NEIL2 protects against oxidative DNA damage induced by sidestream smoke in human cells

PloS one, 2014-03, Vol.9 (3), p.e90261

2014

Volltextzugriff (PDF)

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

Molecular and Cellular Biology, 2008-12, Vol.28 (23), p.7066-7080

2008

Volltextzugriff (PDF)

Acetylation of Human 8-Oxoguanine-DNA Glycosylase by p300 and Its Role in 8-Oxoguanine Repair In Vivo

Molecular and Cellular Biology, 2006-03, Vol.26 (5), p.1654-1665

2006

Volltextzugriff (PDF)

Enhancement of NEIL1 Protein-initiated Oxidized DNA Base Excision Repair by Heterogeneous Nuclear Ribonucleoprotein U (hnRNP-U) via Direct Interaction

The Journal of biological chemistry, 2012-10, Vol.287 (41), p.34202-34211

2012

Volltextzugriff (PDF)

Identification and Characterization of a Human DNA Glycosylase for Repair of Modified Bases in Oxidatively Damaged DNA

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (6), p.3523-3528

2002

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Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes

The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis

Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3

Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells

Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription

Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2

Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation

Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine

Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells

Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection

Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

Functions of disordered regions in mammalian early base excision repair proteins

Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome

Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions

NEIL2 protects against oxidative DNA damage induced by sidestream smoke in human cells

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

Acetylation of Human 8-Oxoguanine-DNA Glycosylase by p300 and Its Role in 8-Oxoguanine Repair In Vivo

Enhancement of NEIL1 Protein-initiated Oxidized DNA Base Excision Repair by Heterogeneous Nuclear Ribonucleoprotein U (hnRNP-U) via Direct Interaction

Identification and Characterization of a Human DNA Glycosylase for Repair of Modified Bases in Oxidatively Damaged DNA

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