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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

Neurobiology of disease, 2013-03, Vol.51, p.35-42

2013

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role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease

Journal of bioenergetics and biomembranes, 2009-12, Vol.41 (6), p.469-472

Hastings, Teresa G

2009

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LRRK2 activation in idiopathic Parkinson's disease

Science translational medicine, 2018-07, Vol.10 (451)

2018

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α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease

Science translational medicine, 2016-06, Vol.8 (342), p.342ra78

2016

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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease

Neurobiology of disease, 2020-02, Vol.134, p.104626-104626, Article 104626

2020

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NADPH oxidase 2 activity in Parkinson's disease

Neurobiology of disease, 2022-08, Vol.170, p.105754-105754, Article 105754

2022

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shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

The Journal of clinical investigation, 2015-07, Vol.125 (7), p.2721-2735

2015

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Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4

Free radical biology & medicine, 2013-12, Vol.65, p.419-427

2013

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Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone

Neurobiology of disease, 2016-07, Vol.91, p.247-261

2016

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Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

Neurobiology of disease, 2009-06, Vol.34 (3), p.487-500

2009

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Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

The Journal of neuroscience, 2008-01, Vol.28 (2), p.425-433

2008

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Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis

The Journal of neuroscience, 2002-10, Vol.22 (20), p.8951-8960

2002

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Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade

The Journal of neuroscience, 2011-01, Vol.31 (1), p.247-261

2011

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Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

Experimental neurology, 2004-05, Vol.187 (1), p.47-57

2004

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Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease

Neurobiology of disease, 2008-03, Vol.29 (3), p.477-489

2008

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Could a loss of α‐synuclein function put dopaminergic neurons at risk?

Journal of neurochemistry, 2004-06, Vol.89 (6), p.1318-1324

2004

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Leptin Protects against 6-Hydroxydopamine-induced Dopaminergic Cell Death via Mitogen-activated Protein Kinase Signaling

The Journal of biological chemistry, 2007-11, Vol.282 (47), p.34479-34491

2007

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Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

The Journal of neuroscience, 1999-02, Vol.19 (4), p.1484-1491

1999

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Alpha‐synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

Journal of neurochemistry, 2006-11, Vol.99 (4), p.1188-1196

2006

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Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine

Journal of neurochemistry, 2008-07, Vol.106 (1), p.333-346

2008

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comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

Journal of neurochemistry, 2007-09, Vol.102 (6), p.2118-2131

2007

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Role of Oxidation in the Neurotoxic Effects of Intrastriatal Dopamine Injections

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (5), p.1956-1961

1996

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Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease

Biochemical pharmacology, 2005-11, Vol.70 (9), p.1371-1381

2005

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Cytotoxic and genotoxic potential of dopamine

Journal of neuroscience research, 1999-03, Vol.55 (6), p.659-665

1999

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Age‐dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria

Journal of neurochemistry, 2002-06, Vol.81 (6), p.1273-1284

2002

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Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease

LRRK2 activation in idiopathic Parkinson's disease

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease

NADPH oxidase 2 activity in Parkinson's disease

shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4

Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis

Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease

Could a loss of α‐synuclein function put dopaminergic neurons at risk?

Leptin Protects against 6-Hydroxydopamine-induced Dopaminergic Cell Death via Mitogen-activated Protein Kinase Signaling

Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

Alpha‐synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine

comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

Role of Oxidation in the Neurotoxic Effects of Intrastriatal Dopamine Injections

Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease

Cytotoxic and genotoxic potential of dopamine

Age‐dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria

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