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Alzheimer's disease biomarkers and the tyranny of treatment

EBioMedicine, 2024-10, Vol.108, p.105291, Article 105291

2024

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Frameworks for estimating causal effects in observational settings: comparing confounder adjustment and instrumental variables

BMC medical research methodology, 2023-05, Vol.23 (1), p.122-24, Article 122

2023

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Estimating attrition in mild-to-moderate Alzheimer's disease and mild cognitive impairment clinical trials

Alzheimer's research & therapy, 2023-11, Vol.15 (1), p.203-203, Article 203

2023

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Study partners should be required in preclinical Alzheimer's disease trials

Alzheimer's research & therapy, 2017-12, Vol.9 (1), p.93-93, Article 93

2017

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The approval of Aduhelm risks eroding public trust in Alzheimer research and the FDA

Nature reviews. Neurology, 2021-09, Vol.17 (9), p.523-524

2021

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Recruitment across two decades of NIH-funded Alzheimer's disease clinical trials

Alzheimer's research & therapy, 2023-02, Vol.15 (1), p.28-28, Article 28

2023

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Effect of study partner on the conduct of Alzheimer disease clinical trials

Neurology, 2013-01, Vol.80 (3), p.282-288

2013

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Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial

JAMA neurology, 2015-11, Vol.72 (11), p.1324

2015

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Current therapeutic targets for the treatment of Alzheimer's disease

Expert review of neurotherapeutics, 2010-05, Vol.10 (5), p.711-728

2010

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Recruitment and retention of participant and study partner dyads in two multinational Alzheimer's disease registration trials

Alzheimer's research & therapy, 2021-01, Vol.13 (1), p.16-16, Article 16

2021

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Reactions to learning a "not elevated" amyloid PET result in a preclinical Alzheimer's disease trial

Alzheimer's research & therapy, 2018-12, Vol.10 (1), p.125-125, Article 125

2018

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Research attitudes in families of individuals with Down syndrome: importance for clinical trials

Alzheimer's research & therapy, 2022-11, Vol.14 (1), p.176-176, Article 176

2022

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Disclosing Alzheimer Disease Biomarker Results to Research Participants

JAMA neurology, 2022-07, Vol.79 (7), p.645

2022

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Asian Americans' and Pacific Islanders' preferences in recruitment strategies and messaging for participation in the CARE registry: A discrete choice experiment

Alzheimer's & dementia, 2023-11, Vol.19 (11), p.5198-5208

2023

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Study partner types and prediction of cognitive performance: implications to preclinical Alzheimer's trials

Alzheimer's research & therapy, 2019-11, Vol.11 (1), p.92-92, Article 92

2019

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A semi-automated virtual workflow solution for the design and production of intraoral molding plates using additive manufacturing: the first clinical results of a pilot-study

Scientific reports, 2018-08, Vol.8 (1), p.11845-11845, Article 11845

2018

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Deciding with Others: Interdependent Decision‐Making

The Hastings Center report, 2022-11, Vol.52 (6), p.23-32

2022

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Participant–Informant Relationships Affect Quality of Life Ratings in Incipient and Clinical Alzheimer Disease

The American journal of geriatric psychiatry, 2017-03, Vol.25 (3), p.297-307

2017

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Comparison of three-dimensional imaging of the nose using three different 3D-photography systems: an observational study

Head & face medicine, 2024-01, Vol.20 (1), p.7-10, Article 7

2024

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Participant and study partner prediction and identification of cognitive impairment in preclinical Alzheimer's disease: study partner vs. participant accuracy

Alzheimer's research & therapy, 2019-10, Vol.11 (1), p.85-85, Article 85

2019

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Reasons for undergoing amyloid imaging among cognitively unimpaired older adults

Annals of clinical and translational neurology, 2021-08, Vol.8 (8), p.1646-1655

2021

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Attitudes toward clinical trials across the Alzheimer's disease spectrum

Alzheimer's research & therapy, 2017-10, Vol.9 (1), p.81-81, Article 81

2017

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Implications of FDA Approval of a First Disease-Modifying Therapy for a Neurodegenerative Disease on the Design of Subsequent Clinical Trials

Neurology, 2021-09, Vol.97 (10), p.496-500

2021

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A Scoping Review of Dietary Factors Conferring Risk or Protection for Cognitive Decline in APOE ε4 Carriers

The Journal of nutrition, health & aging, 2021, Vol.25 (10), p.1167-1178

2021

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Testing for Alzheimer Disease Biomarkers and Disclosing Results Across the Disease Continuum

Neurology, 2023-05, Vol.100 (21), p.1010-1019

2023

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Alzheimer's disease biomarkers and the tyranny of treatment

Frameworks for estimating causal effects in observational settings: comparing confounder adjustment and instrumental variables

Estimating attrition in mild-to-moderate Alzheimer's disease and mild cognitive impairment clinical trials

Study partners should be required in preclinical Alzheimer's disease trials

The approval of Aduhelm risks eroding public trust in Alzheimer research and the FDA

Recruitment across two decades of NIH-funded Alzheimer's disease clinical trials

Effect of study partner on the conduct of Alzheimer disease clinical trials

Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial

Current therapeutic targets for the treatment of Alzheimer's disease

Recruitment and retention of participant and study partner dyads in two multinational Alzheimer's disease registration trials

Reactions to learning a "not elevated" amyloid PET result in a preclinical Alzheimer's disease trial

Research attitudes in families of individuals with Down syndrome: importance for clinical trials

Disclosing Alzheimer Disease Biomarker Results to Research Participants

Asian Americans' and Pacific Islanders' preferences in recruitment strategies and messaging for participation in the CARE registry: A discrete choice experiment

Study partner types and prediction of cognitive performance: implications to preclinical Alzheimer's trials

A semi-automated virtual workflow solution for the design and production of intraoral molding plates using additive manufacturing: the first clinical results of a pilot-study

Deciding with Others: Interdependent Decision‐Making

Participant–Informant Relationships Affect Quality of Life Ratings in Incipient and Clinical Alzheimer Disease

Comparison of three-dimensional imaging of the nose using three different 3D-photography systems: an observational study

Participant and study partner prediction and identification of cognitive impairment in preclinical Alzheimer's disease: study partner vs. participant accuracy

Reasons for undergoing amyloid imaging among cognitively unimpaired older adults

Attitudes toward clinical trials across the Alzheimer's disease spectrum

Implications of FDA Approval of a First Disease-Modifying Therapy for a Neurodegenerative Disease on the Design of Subsequent Clinical Trials

A Scoping Review of Dietary Factors Conferring Risk or Protection for Cognitive Decline in APOE ε4 Carriers

Testing for Alzheimer Disease Biomarkers and Disclosing Results Across the Disease Continuum

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