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Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia

Haematologica (Roma), 2024-10, Vol.109 (10), p.3167-3181

2024

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JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma

Blood, 2011-04, Vol.117 (15), p.4056-4064

2011

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PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia

Journal of hematology and oncology, 2021-06, Vol.14 (1), p.97-14, Article 97

2021

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NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins

Haematologica (Roma), 2014-01, Vol.99 (1), p.85-93

2014

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The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Journal of hematology and oncology, 2018-08, Vol.11 (1), p.108-108, Article 108

2018

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Kinase Activation and Transformation by NUP214-ABL1 Is Dependent on the Context of the Nuclear Pore

Molecular cell, 2008-07, Vol.31 (1), p.134-142

2008

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JAK1 mutation analysis in T-cell acute lymphoblastic leukemia cell lines

Haematologica (Roma), 2009-03, Vol.94 (3), p.435-437

2009

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JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model

Blood, 2014-11, Vol.124 (20), p.3092-3100

2014

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Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping

American journal of hematology, 2022-05, Vol.97 (5), p.548-561

2022

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Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Blood, 2019-10, Vol.134 (16), p.1323-1336

2019

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Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

Blood, 2022-12, Vol.140 (23), p.2463-2476

2022

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The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia

Clinical cancer research, 2020-11, Vol.26 (21), p.5747-5758

2020

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HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development

Cancer discovery, 2018-05, Vol.8 (5), p.616-631

2018

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Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors

Blood, 2016-12, Vol.128 (23), p.2642-2654

2016

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Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities

The Journal of biological chemistry, 2015-11, Vol.290 (48), p.29022-29034

2015

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Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL

Blood, 2018-01, Vol.131 (4), p.421-425

2018

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Development of a siRNA and shRNA screening system based on a kinase fusion protein

RNA (Cambridge), 2012-06, Vol.18 (6), p.1296-1306

2012

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The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V

Molecular oncology, 2014-05, Vol.8 (3), p.728-740

2014

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Parent-Child Role Reversal and Psychological Adjustment Among Immigrant Youth in Israel

Journal of family psychology, 2009-06, Vol.23 (3), p.405-415

2009

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Endomyocardial biopsy: safety and prognostic utility in paediatric and adult myocarditis in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocarditis Long-Term Registry

European heart journal, 2024-07, Vol.45 (28), p.2548-2569

2024

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Towards a closed-loop system for stimulation and recording: An in vitro approach with embryonic cardiomyocytes

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010-01, Vol.2010, p.2735-2738

2010

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Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma

PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Kinase Activation and Transformation by NUP214-ABL1 Is Dependent on the Context of the Nuclear Pore

JAK1 mutation analysis in T-cell acute lymphoblastic leukemia cell lines

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model

Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors

Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities

Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL

Development of a siRNA and shRNA screening system based on a kinase fusion protein

The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

Parent-Child Role Reversal and Psychological Adjustment Among Immigrant Youth in Israel

Endomyocardial biopsy: safety and prognostic utility in paediatric and adult myocarditis in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocarditis Long-Term Registry

Towards a closed-loop system for stimulation and recording: An in vitro approach with embryonic cardiomyocytes

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