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Protein kinase A‐mediated phosphorylation of naked cuticle homolog 2 stimulates cell‐surface delivery of transforming growth factor‐α for epidermal growth factor receptor transactivation

Traffic (Copenhagen, Denmark), 2019-05, Vol.20 (5), p.357-368

2019

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Transfer of Functional Cargo in Exomeres

Cell reports (Cambridge), 2019-04, Vol.27 (3), p.940-954.e6

2019

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Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells

Molecular biology of the cell, 2017-05, Vol.28 (10), p.1288-1300

2017

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TACE/ADAM-17: A Component of the Epidermal Growth Factor Receptor Axis and a Promising Therapeutic Target in Colorectal Cancer

Clinical cancer research, 2008-02, Vol.14 (4), p.1182-1191

2008

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Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium

Journal of cellular physiology, 2007-03, Vol.210 (3), p.740-749

2007

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Use of Fluorescence-activated Vesicle Sorting for Isolation of Naked2-associated, Basolaterally Targeted Exocytic Vesicles for Proteomics Analysis

Molecular & cellular proteomics, 2008-09, Vol.7 (9), p.1651-1667

2008

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Myristoylated Naked2 Escorts Transforming Growth Factor α to the Basolateral Plasma Membrane of Polarized Epithelial Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (15), p.5571-5576

2004

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EGF receptor-independent action of TGF-α protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (36), p.13433-13438

2008

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Epidermal Growth Factor Receptor Activation Induces Nuclear Targeting of Cyclooxygenase-2, Basolateral Release of Prostaglandins, and Mitogenesis in Polarizing Colon Cancer Cells

Proceedings of the National Academy of Sciences - PNAS, 1997-01, Vol.94 (2), p.657-662

1997

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lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Nature medicine, 2017-11, Vol.23 (11), p.1331-1341

2017

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Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets

Nature cell biology, 2021-12, Vol.23 (12), p.1240-1254

2021

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A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells

The Journal of biological chemistry, 1997-07, Vol.272 (30), p.18926-18931

1997

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Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.28, Article 28

2024

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Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

The Journal of clinical investigation, 2014-05, Vol.124 (5), p.2172-2187

2014

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KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling

Theranostics, 2020-01, Vol.10 (16), p.7335-7350

2020

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Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (14), p.E2852-E2861

2017

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Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

Integrative biology (Cambridge), 2021-06, Vol.13 (6), p.153-166

2021

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Differential effects of amphiregulin and TGF-α on the morphology of MDCK cells

Experimental cell research, 2005-09, Vol.309 (1), p.149-160

2005

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Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells

Cancer research (Chicago, Ill.), 2003-04, Vol.63 (8), p.1748-1751

2003

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Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m 6 A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

Molecular cancer, 2022-03, Vol.21 (1), p.74

2022

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Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells

Molecular biology of the cell, 2007-08, Vol.18 (8), p.3081-3093

2007

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Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family

The Journal of biological chemistry, 1994-09, Vol.269 (36), p.22817-22822

1994

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Transforming growth factors and related peptides in gastrointestinal neoplasia

Journal of cellular biochemistry, 1992, Vol.50 (S16G), p.111-118

1992

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Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione

Biochimica et biophysica acta, 2002-09, Vol.1584 (1), p.37

2002

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Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas

Cancer research (Chicago, Ill.), 1992-06, Vol.52 (11), p.3224-3227

1992

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Protein kinase A‐mediated phosphorylation of naked cuticle homolog 2 stimulates cell‐surface delivery of transforming growth factor‐α for epidermal growth factor receptor transactivation

Transfer of Functional Cargo in Exomeres

Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells

TACE/ADAM-17: A Component of the Epidermal Growth Factor Receptor Axis and a Promising Therapeutic Target in Colorectal Cancer

Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium

Use of Fluorescence-activated Vesicle Sorting for Isolation of Naked2-associated, Basolaterally Targeted Exocytic Vesicles for Proteomics Analysis

Myristoylated Naked2 Escorts Transforming Growth Factor α to the Basolateral Plasma Membrane of Polarized Epithelial Cells

EGF receptor-independent action of TGF-α protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

Epidermal Growth Factor Receptor Activation Induces Nuclear Targeting of Cyclooxygenase-2, Basolateral Release of Prostaglandins, and Mitogenesis in Polarizing Colon Cancer Cells

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets

A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells

Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

Differential effects of amphiregulin and TGF-α on the morphology of MDCK cells

Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m 6 A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells

Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family

Transforming growth factors and related peptides in gastrointestinal neoplasia

Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione

Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas

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