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Pharmacokinetics and Pharmacodynamics of AR9281, an Inhibitor of Soluble Epoxide Hydrolase, in Single- and Multiple-Dose Studies in Healthy Human Subjects

Journal of clinical pharmacology, 2012-03, Vol.52 (3), p.319-328

2012

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1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.983-988

2011

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Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1066-1070

2009

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Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase

Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5212-5216

2006

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Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolase

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4259-4263

2009

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CHARACTERIZATION OF CELL LINES DEVELOPED FROM THE GLASSY-WINGED SHARPSHOOTER, HOMALODISCA COAGULATA (HEMIPTERA: CICADELLIDAE)

In vitro cellular & developmental biology. Animal, 2005-05, Vol.41 (5), p.149-153

2005

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Postoperative Delirium in the Elderly : Risk Factors and Outcomes

Annals of surgery, 2009, Vol.249 (1), p.173-178

2009

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Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2020-10, Vol.324 (13), p.1307

2020

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Postoperative falls in the acute hospital setting: characteristics, risk factors, and outcomes in males

The American journal of surgery, 2011-02, Vol.201 (2), p.197-202

2011

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De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction

Diabetes (New York, N.Y.), 2020-03, Vol.69 (3), p.477-483

2020

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Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial

Journal of the American Geriatrics Society (JAGS), 2014-09, Vol.62 (9), p.1764-1771

2014

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Risk factors for delirium after major trauma

The American journal of surgery, 2008-12, Vol.196 (6), p.864-870

2008

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Pharmacokinetics of Single-Dose Intravenous Ketorolac in Infants Aged 2―11 Months

Anesthesia and analgesia, 2011-03, Vol.112 (3), p.655-660

2011

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Cancer Patient and Survivor Research From the Cancer Information Service Research Consortium: A Preview of Three Large Randomized Trials and Initial Lessons Learned

Journal of health communication, 2013-05, Vol.18 (5), p.543-562

2013

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Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

Nature communications, 2023-06, Vol.14 (1), p.3403-3403, Article 3403

2023

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Structure−Activity Relationship for Noncoplanar Polychlorinated Biphenyl Congeners toward the Ryanodine Receptor-Ca2+ Channel Complex Type 1 (RyR1)

Chemical research in toxicology, 2006-01, Vol.19 (1), p.92-101

2006

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Motor subtypes of postoperative delirium in older adults

Archives of surgery (Chicago. 1960), 2011-03, Vol.146 (3), p.295

2011

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Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: the Midwest Exercise Trial

Archives of internal medicine (1960), 2003-06, Vol.163 (11), p.1343

2003

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Type 1 diabetes in Jewish Ethiopian immigrants in Israel: HLA class II immunogenetics and contribution of new environment

Human immunology, 2004-12, Vol.65 (12), p.1463-1468

2004

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Biodegradation of the polyhydroxylcanoates(PGA) in the Eastern Sea and identification of PGA-degrading bacteria

Mikrobiologija (Moskva. 1932), 2011-03, Vol.80 (2), p.266

2011

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Interrelationship between insulin, leptin and growth hormone in growth hormone-treated children

International Journal of Obesity, 2001-04, Vol.25 (4), p.538-542

2001

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Surface-enhanced Raman spectroscopy of the catecholamine neurotransmitters and related compounds

Analytical chemistry (Washington), 1988-03, Vol.60 (5), p.442-446

1988

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[3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus

The Journal of pharmacology and experimental therapeutics, 1993-11, Vol.267 (2), p.961

1993

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Effect of polymorphism in insulin locus and HLA on type 1 diabetes in four ethnic groups in Israel

Tissue antigens, 2009-01, Vol.73 (1), p.33-38

2009

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Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells

European journal of pharmacology, 1993-01, Vol.244 (1), p.49-55

1993

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Pharmacokinetics and Pharmacodynamics of AR9281, an Inhibitor of Soluble Epoxide Hydrolase, in Single- and Multiple-Dose Studies in Healthy Human Subjects

1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors

Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase

Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolase

CHARACTERIZATION OF CELL LINES DEVELOPED FROM THE GLASSY-WINGED SHARPSHOOTER, HOMALODISCA COAGULATA (HEMIPTERA: CICADELLIDAE)

Postoperative Delirium in the Elderly : Risk Factors and Outcomes

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

Postoperative falls in the acute hospital setting: characteristics, risk factors, and outcomes in males

De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction

Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial

Risk factors for delirium after major trauma

Pharmacokinetics of Single-Dose Intravenous Ketorolac in Infants Aged 2―11 Months

Cancer Patient and Survivor Research From the Cancer Information Service Research Consortium: A Preview of Three Large Randomized Trials and Initial Lessons Learned

Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

Structure−Activity Relationship for Noncoplanar Polychlorinated Biphenyl Congeners toward the Ryanodine Receptor-Ca2+ Channel Complex Type 1 (RyR1)

Motor subtypes of postoperative delirium in older adults

Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: the Midwest Exercise Trial

Type 1 diabetes in Jewish Ethiopian immigrants in Israel: HLA class II immunogenetics and contribution of new environment

Biodegradation of the polyhydroxylcanoates(PGA) in the Eastern Sea and identification of PGA-degrading bacteria

Interrelationship between insulin, leptin and growth hormone in growth hormone-treated children

Surface-enhanced Raman spectroscopy of the catecholamine neurotransmitters and related compounds

[3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus

Effect of polymorphism in insulin locus and HLA on type 1 diabetes in four ethnic groups in Israel

Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells

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