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Autophagy Activation in Asthma Airways Remodeling

American journal of respiratory cell and molecular biology, 2019-05, Vol.60 (5), p.541-553

2019

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Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Nature (London), 2015-11, Vol.527 (7579), p.477-483

2015

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Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

Nature medicine, 2010-11, Vol.16 (11), p.1299-1304

2010

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Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice

Scientific reports, 2017-04, Vol.7 (1), p.46166-46166, Article 46166

2017

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OGR1-dependent regulation of the allergen-induced asthma phenotype

American journal of physiology. Lung cellular and molecular physiology, 2021-12, Vol.321 (6), p.L1044-L1054

2021

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Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation

Respiratory research, 2023-06, Vol.24 (1), p.155-10, Article 155

2023

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Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma

International journal of molecular sciences, 2022-10, Vol.23 (19), p.11868

2022

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Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

The FASEB journal, 2018-02, Vol.32 (2), p.862-874

2018

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Cooperativity of E‐prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle

The FASEB journal, 2019-04, Vol.33 (4), p.4780-4789

2019

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Mapping Functional Group Free Energy Patterns at Protein Occluded Sites: Nuclear Receptors and G‑Protein Coupled Receptors

Journal of chemical information and modeling, 2015-03, Vol.55 (3), p.700-708

2015

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Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells

PloS one, 2015-06, Vol.10 (6), p.e0131582

2015

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Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease

Clinical science (1979), 2018-07, Vol.132 (14), p.1615-1627

2018

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Regulation of ovarian cancer G protein-coupled receptor-1 expression and signaling

American journal of physiology. Lung cellular and molecular physiology, 2019-05, Vol.316 (5), p.L894-L902

2019

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CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

Mediators of inflammation, 2018-01, Vol.2018 (2018), p.1-10

2018

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CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models

Canadian journal of physiology and pharmacology, 2015-02, Vol.93 (2), p.145-153

2015

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Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma

American journal of physiology. Lung cellular and molecular physiology, 2024-07, Vol.327 (1), p.L3-L18

2024

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Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?

European journal of pharmacology, 2021-04, Vol.897, p.173928-173928, Article 173928

2021

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Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca 2+ Signaling in Airway Smooth Muscle

American journal of respiratory cell and molecular biology, 2023-12, Vol.69 (6), p.605-607

2023

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Mitochondrial regulation of airway smooth muscle functions in health and pulmonary diseases

Archives of biochemistry and biophysics, 2019-03, Vol.663, p.109-119

2019

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Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells

American journal of physiology. Lung cellular and molecular physiology, 2017-07, Vol.313 (1), p.L154-L165

2017

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A cryptic mode of GPCR regulation revealed

Trends in molecular medicine, 2022-11, Vol.28 (11), p.900-901

2022

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Reply to Letter to the Editor: "Bnip3 as a potential target to treat airway smooth muscle remodeling in asthma?"

American journal of physiology. Lung cellular and molecular physiology, 2020-01, Vol.318 (1), p.L213-L214

2020

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Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma

The FASEB journal, 2021-12, Vol.35 (12), p.e22016-n/a

2021

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CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle

American journal of physiology. Lung cellular and molecular physiology, 2005-05, Vol.288 (5), p.L773-L788

2005

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Effects of ATP‐competitive and function‐selective ERK inhibitors on airway smooth muscle cell proliferation

The FASEB journal, 2019-10, Vol.33 (10), p.10833-10843

2019

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Autophagy Activation in Asthma Airways Remodeling

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice

OGR1-dependent regulation of the allergen-induced asthma phenotype

Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma

Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

Cooperativity of E‐prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle

Mapping Functional Group Free Energy Patterns at Protein Occluded Sites: Nuclear Receptors and G‑Protein Coupled Receptors

Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells

Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease

Regulation of ovarian cancer G protein-coupled receptor-1 expression and signaling

CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models

Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma

Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?

Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca 2+ Signaling in Airway Smooth Muscle

Mitochondrial regulation of airway smooth muscle functions in health and pulmonary diseases

Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells

A cryptic mode of GPCR regulation revealed

Reply to Letter to the Editor: "Bnip3 as a potential target to treat airway smooth muscle remodeling in asthma?"

Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma

CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle

Effects of ATP‐competitive and function‐selective ERK inhibitors on airway smooth muscle cell proliferation

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