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The new antihypertensive drug iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels

Acta pharmacologica Sinica, 2015-12, Vol.36 (12), p.1444-1450

2015

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Pharmacological evidence： a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells

Acta pharmacologica Sinica, 2017-01, Vol.38 (1), p.41-55

2017

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Proteomics reveals potential non-neuronal cholinergic receptor-effectors in endothelial cells

Acta pharmacologica Sinica, 2014-09, Vol.35 (9), p.1137-1149

2014

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POTASSIUM CHANNEL CURRENTS IN RAT MESENCHYMAL STEM CELLS AND THEIR POSSIBLE ROLES IN CELL PROLIFERATION

Clinical and experimental pharmacology & physiology, 2008-09, Vol.35 (9), p.1077-1084

2008

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Single-dose pharmacokinetics and safety of iptakalim hydrochloride in Chinese healthy volunteers

Journal of pharmacy and pharmacology, 2012-03, Vol.64 (3), p.337-343

2012

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The novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function

Acta pharmacologica Sinica, 2011-12, Vol.32 (12), p.1466-1474

2011

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Stimulation of endothelial non-neuronal muscarinic receptor attenuates the progression of atherosclerosis via inhibiting endothelial cells activation

Zhongguo ying yong sheng li xue za zhi, 2014-11, Vol.30 (6), p.549

2014

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Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons

Acta pharmacologica Sinica, 2016-03, Vol.37 (3), p.312-321

2016

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Synergisms of cardiovascular effects between iptakalim and amlodipine, hydrochlorothiazide or propranolol in anesthetized rats

Zhongguo ying yong sheng li xue za zhi, 2015-11, Vol.31 (6), p.532

2015

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Sensitivity of KATp channels to cellular metabolic disorders and the underlying structural basis

Acta pharmacologica Sinica, 2016, Vol.37 (1), p.134-142

2016

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Proteomic identification of human serum biomarkers associated with high altitude pulmonary edema

Zhongguo ying yong sheng li xue za zhi, 2013-11, Vol.29 (6), p.501

2013

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Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy

International journal of molecular medicine, 2014-11, Vol.34 (5), p.1209-1218

2014

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Association of the antihypertensive response of iptakalim with KCNJ11 (Kir6.2 gene) polymorphisms in Chinese Han hypertensive patients

Acta pharmacologica Sinica, 2011-08, Vol.32 (8), p.1078-1084

2011

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Stimulation of non-neuronal muscarinic receptors enhances chemerin/ChemR23 system in dysfunctional endothelial cells

Life sciences (1973), 2013-01, Vol.92 (1), p.10-16

2013

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Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia

Journal of hypertension, 2008-12, Vol.26 (12), p.2326-2338

2008

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Bioavailability, tissue distribution, and excretion characteristics of the novel carbonic anhydrase inhibitor tolsultazolamide in rats

Acta pharmacologica Sinica, 2014-02, Vol.35 (2), p.275-282

2014

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Molecular of pulmonary arterioles relaxation through SUR2B/Kir6.1 channel opening

Zhongguo ying yong sheng li xue za zhi, 2016-03, Vol.32 (3), p.238

2016

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Choline promotes angiogenesis in chick embryo chorioallantoic membrane

Zhongguo ying yong sheng li xue za zhi, 2013-05, Vol.29 (3), p.229

2013

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Construction of T vectors based on Xcm I recognition site and optimization of PCR fragments for ligation

Zhongguo ying yong sheng li xue za zhi, 2016-01, Vol.32 (1), p.46

2016

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Novel drug composition ameliorating thrombosis and its molecular mechanisms

Zhongguo ying yong sheng li xue za zhi, 2014-03, Vol.30 (2), p.184

2014

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Pathophysiological characteristics of rat pulmonary hypertension and cor pulmonale induced by monocrotaline

Zhongguo ying yong sheng li xue za zhi, 2012-05, Vol.28 (3), p.193

2012

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Genome-wide association study of high altitude pulmonary edema

Zhongguo ying yong sheng li xue za zhi, 2014-03, Vol.30 (2), p.101

2014

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The effect of hypothermia on the vasoconstriction and vasodilatation and concerned with vasoactive drugs

Zhongguo ying yong sheng li xue za zhi, 2014-05, Vol.30 (3), p.204

2014

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The construction and application of a novel apparatus for detecting oxygen consumption of mice under normobaric hypoxia

Zhongguo ying yong sheng li xue za zhi, 2014-07, Vol.30 (4), p.382

2014

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Effects of ATP-sensitive potassium channel opener iptakalim against ventricular remodeling and its mechanisms of endothelial protection

Zhongguo ying yong sheng li xue za zhi, 2013-05, Vol.29 (3), p.205

2013

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The new antihypertensive drug iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels

Pharmacological evidence： a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells

Proteomics reveals potential non-neuronal cholinergic receptor-effectors in endothelial cells

POTASSIUM CHANNEL CURRENTS IN RAT MESENCHYMAL STEM CELLS AND THEIR POSSIBLE ROLES IN CELL PROLIFERATION

Single-dose pharmacokinetics and safety of iptakalim hydrochloride in Chinese healthy volunteers

The novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function

Stimulation of endothelial non-neuronal muscarinic receptor attenuates the progression of atherosclerosis via inhibiting endothelial cells activation

Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons

Synergisms of cardiovascular effects between iptakalim and amlodipine, hydrochlorothiazide or propranolol in anesthetized rats

Sensitivity of KATp channels to cellular metabolic disorders and the underlying structural basis

Proteomic identification of human serum biomarkers associated with high altitude pulmonary edema

Natakalim improves post-infarction left ventricular remodeling by restoring the coordinated balance between endothelial function and cardiac hypertrophy

Association of the antihypertensive response of iptakalim with KCNJ11 (Kir6.2 gene) polymorphisms in Chinese Han hypertensive patients

Stimulation of non-neuronal muscarinic receptors enhances chemerin/ChemR23 system in dysfunctional endothelial cells

Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia

Bioavailability, tissue distribution, and excretion characteristics of the novel carbonic anhydrase inhibitor tolsultazolamide in rats

Molecular of pulmonary arterioles relaxation through SUR2B/Kir6.1 channel opening

Choline promotes angiogenesis in chick embryo chorioallantoic membrane

Construction of T vectors based on Xcm I recognition site and optimization of PCR fragments for ligation

Novel drug composition ameliorating thrombosis and its molecular mechanisms

Pathophysiological characteristics of rat pulmonary hypertension and cor pulmonale induced by monocrotaline

Genome-wide association study of high altitude pulmonary edema

The effect of hypothermia on the vasoconstriction and vasodilatation and concerned with vasoactive drugs

The construction and application of a novel apparatus for detecting oxygen consumption of mice under normobaric hypoxia

Effects of ATP-sensitive potassium channel opener iptakalim against ventricular remodeling and its mechanisms of endothelial protection

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