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Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (2)

2021

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Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Toxicology letters, 2017-01, Vol.265, p.86-96

2017

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Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms

Pharmacological reports, 2023-02, Vol.75 (1), p.177-188

2023

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Access of inhibitory neurosteroids to the NMDA receptor

British journal of pharmacology, 2012-06, Vol.166 (3), p.1069-1083

2012

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Structure activity relationship studies on cytotoxicity and the effects on steroid receptors of AB-functionalized cholestanes

The Journal of steroid biochemistry and molecular biology, 2016-05, Vol.159, p.154-169

2016

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Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia

Biomolecules (Basel, Switzerland), 2021-07, Vol.11 (7), p.1026

2021

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Stereoselectivity of sodium borohydride reduction of saturated steroidal ketones utilizing conditions of Luche reduction

Steroids, 2010-10, Vol.75 (10), p.721-725

2010

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Synthetic structural modifications of neurosteroid pregnanolone sulfate: Assessment of neuroprotective effects in vivo

European journal of pharmacology, 2020-08, Vol.881, p.173187-173187, Article 173187

2020

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Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

Diabetes (New York, N.Y.), 2020-03, Vol.69 (3), p.300-312

2020

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Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor

The Journal of neuroscience, 2020-07, Vol.40 (31), p.5922-5936

2020

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Azido analogs of neuroactive steroids

Steroids, 2011-09, Vol.76 (10), p.1043-1050

2011

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Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.36-36, Article 36

2024

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Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

British journal of pharmacology, 2021-10, Vol.178 (19), p.3888-3904

2021

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5β-reduced neuroactive steroids as modulators of growth and viability of postnatal neurons and glia

The Journal of steroid biochemistry and molecular biology, 2024-05, Vol.239, p.106464, Article 106464

2024

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A New Class of Potent N‑Methyl‑d‑Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D‑Ring Modifications

Journal of medicinal chemistry, 2015-08, Vol.58 (15), p.5950-5966

2015

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Pregn-5-en-3β-ol and androst-5-en-3β-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability

Steroids, 2019-07, Vol.147, p.4-9

2019

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Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives

The Journal of neuroscience, 2016-02, Vol.36 (7), p.2161-2175

2016

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Effects of steroids on NMDA receptors and excitatory synaptic transmission in neonatal motoneurons in rat spinal cord slices

The European journal of neuroscience, 2001-08, Vol.14 (3), p.495-502

2001

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Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule

Scientific reports, 2015-06, Vol.5 (1), p.10935-10935, Article 10935

2015

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Neurosteroid-like Inhibitors of N‑Methyl‑d‑aspartate Receptor: Substituted 2‑Sulfates and 2‑Hemisuccinates of Perhydrophenanthrene

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4724-4739

2016

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Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors

Steroids, 2017-01, Vol.117, p.52-61

2017

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Neurosteroid modulation of N-methyl- d-aspartate receptors: Molecular mechanism and behavioral effects

Steroids, 2011-12, Vol.76 (13), p.1409-1418

2011

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3α5β-Pregnanolone glutamate, a use-dependent NMDA antagonist, reversed spatial learning deficit in an animal model of schizophrenia

Behavioural brain research, 2012-11, Vol.235 (1), p.82-88

2012

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Synthesis of 3-methyl-3-hydroxy-6-oxo-androstane derivatives

Steroids, 2004-09, Vol.69 (10), p.605-612

2004

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Molecular Mechanism of Pregnenolone Sulfate Action at NR1/NR2B Receptors

The Journal of neuroscience, 2004-11, Vol.24 (46), p.10318-10325

2004

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Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms

Access of inhibitory neurosteroids to the NMDA receptor

Structure activity relationship studies on cytotoxicity and the effects on steroid receptors of AB-functionalized cholestanes

Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia

Stereoselectivity of sodium borohydride reduction of saturated steroidal ketones utilizing conditions of Luche reduction

Synthetic structural modifications of neurosteroid pregnanolone sulfate: Assessment of neuroprotective effects in vivo

Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor

Azido analogs of neuroactive steroids

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

5β-reduced neuroactive steroids as modulators of growth and viability of postnatal neurons and glia

A New Class of Potent N‑Methyl‑d‑Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D‑Ring Modifications

Pregn-5-en-3β-ol and androst-5-en-3β-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability

Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives

Effects of steroids on NMDA receptors and excitatory synaptic transmission in neonatal motoneurons in rat spinal cord slices

Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule

Neurosteroid-like Inhibitors of N‑Methyl‑d‑aspartate Receptor: Substituted 2‑Sulfates and 2‑Hemisuccinates of Perhydrophenanthrene

Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors

Neurosteroid modulation of N-methyl- d-aspartate receptors: Molecular mechanism and behavioral effects

3α5β-Pregnanolone glutamate, a use-dependent NMDA antagonist, reversed spatial learning deficit in an animal model of schizophrenia

Synthesis of 3-methyl-3-hydroxy-6-oxo-androstane derivatives

Molecular Mechanism of Pregnenolone Sulfate Action at NR1/NR2B Receptors

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