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Autophagy at the intersection of aging, senescence, and cancer

Molecular oncology, 2022-09, Vol.16 (18), p.3259-3275

2022

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Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

Nature communications, 2020-01, Vol.11 (1), p.307-307, Article 307

2020

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IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype

Aging cell, 2019-06, Vol.18 (3), p.e12946-n/a

2019

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Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease

Neurobiology of disease, 2022-12, Vol.175, p.105919, Article 105919

2022

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LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

Journal of proteome research, 2014-04, Vol.13 (4), p.2205-2214

2014

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Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions

Nature communications, 2024-10, Vol.15 (1), p.8659-21, Article 8659

2024

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Fast and simple spectral FLIM for biochemical and medical imaging

Optics express, 2015-09, Vol.23 (18), p.23511-23525

2015

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Quantitative proteome analysis of Caenorhabditis elegans upon exposure to nematicidal Bacillus thuringiensis

Journal of proteomics, 2015-01, Vol.113, p.337-350

2015

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Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer

Cancer cell, 2010-11, Vol.18 (5), p.499

2010

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Alveolar-Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7298

2023

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A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Autophagy, 2018-07, Vol.14 (7), p.1256-1266

2018

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Autophagy and senescence, converging roles in pathophysiology as seen through mouse models

Advances in cancer research, 2021, Vol.150, p.113

2021

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Genome instability mechanisms and the structure of cancer genomes

Current opinion in genetics & development, 2012-02, Vol.22 (1), p.10-13

2012

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Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Molecular oncology, 2014-03, Vol.8 (2), p.161-168

2014

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Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium Difficile Infection

Gastroenterology (New York, N.Y. 1943), 2017-03, Vol.152 (4), p.799-811.e7

2017

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Improved Identification of Proteoforms in Top-Down Proteomics Using FAIMS with Internal CV Stepping

Analytical chemistry (Washington), 2022-03, Vol.94 (8), p.3600-3607

2022

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Small Proteins in Archaea, a Mainly Unexplored World

Journal of bacteriology, 2022-01, Vol.204 (1), p.e0031321-e0031321

2022

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Bottom‐up and top‐down proteomic approaches for the identification, characterization, and quantification of the low molecular weight proteome with focus on short open reading frame‐encoded peptides

Proteomics (Weinheim), 2021-12, Vol.21 (23-24), p.e2100008-n/a

2021

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Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer

Cancer research (Chicago, Ill.), 2022-12, Vol.82 (23), p.4429-4443

2022

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MSTopDiff: A Tool for the Visualization of Mass Shifts in Deconvoluted Top-Down Proteomics Data for the Database-Independent Detection of Protein Modifications

Journal of proteome research, 2022-01, Vol.21 (1), p.20-29

2022

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Combination of Bottom-up 2D-LC-MS and Semi-top-down GelFree-LC-MS Enhances Coverage of Proteome and Low Molecular Weight Short Open Reading Frame Encoded Peptides of the Archaeon Methanosarcina mazei

Journal of proteome research, 2016-10, Vol.15 (10), p.3773-3783

2016

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Model organism proteomics as a tool for the study of host-microbiome interactions

Proteomics. Clinical applications, 2014-10, Vol.8 (9-10), p.665-676

2014

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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Nature cell biology, 2012-02, Vol.14 (2), p.148-158

2012

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Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance

Genes & development, 2022-05, Vol.36 (9-10), p.533-549

2022

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The Caenorhabditis elegans Proteome Response to Naturally Associated Microbiome Members of the Genus Ochrobactrum

Proteomics (Weinheim), 2018-04, Vol.18 (8), p.e1700426-n/a

2018

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Autophagy at the intersection of aging, senescence, and cancer

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype

Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease

LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions

Fast and simple spectral FLIM for biochemical and medical imaging

Quantitative proteome analysis of Caenorhabditis elegans upon exposure to nematicidal Bacillus thuringiensis

Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer

Alveolar-Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3

A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Autophagy and senescence, converging roles in pathophysiology as seen through mouse models

Genome instability mechanisms and the structure of cancer genomes

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium Difficile Infection

Improved Identification of Proteoforms in Top-Down Proteomics Using FAIMS with Internal CV Stepping

Small Proteins in Archaea, a Mainly Unexplored World

Bottom‐up and top‐down proteomic approaches for the identification, characterization, and quantification of the low molecular weight proteome with focus on short open reading frame‐encoded peptides

Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer

MSTopDiff: A Tool for the Visualization of Mass Shifts in Deconvoluted Top-Down Proteomics Data for the Database-Independent Detection of Protein Modifications

Combination of Bottom-up 2D-LC-MS and Semi-top-down GelFree-LC-MS Enhances Coverage of Proteome and Low Molecular Weight Short Open Reading Frame Encoded Peptides of the Archaeon Methanosarcina mazei

Model organism proteomics as a tool for the study of host-microbiome interactions

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance

The Caenorhabditis elegans Proteome Response to Naturally Associated Microbiome Members of the Genus Ochrobactrum

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