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2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

Chemical reviews, 2012-07, Vol.112 (7), p.3641-3716

Borthwick, Alan D

2012

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2,5-diketopiperazines in food and beverages: Taste and bioactivity

Critical reviews in food science and nutrition, 2017-03, Vol.57 (4), p.718-742

2017

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Dynamic professional boundaries in the healthcare workforce

Sociology of health & illness, 2005-11, Vol.27 (7), p.897-919

2005

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Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS Activity and Treatment of Cognitive Dysfunction in Central Neurodegenerative Diseases

Mini reviews in medicinal chemistry, 2017-01, Vol.17 (7), p.572-582

Borthwick, Alan D

2017

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A decade of independent prescribing in the UK: a review of progress

Journal of foot and ankle research, 2022-05, Vol.15 (1), p.35-n/a

2022

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Oral Oxytocin Antagonists

Journal of medicinal chemistry, 2010-09, Vol.53 (18), p.6525-6538

Borthwick, Alan D

2010

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Independent prescribing in the UK: insights from the Department of Health Allied Health Professions Medicines Project team

Journal of foot and ankle research, 2023-07, Vol.16 (1), p.41-n/a

2023

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The mystery of the COVID toes – turning evidence‐based medicine on its head

Journal of foot and ankle research, 2020-06, Vol.13 (1), p.1-n/a

2020

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The design of orally bioavailable 2, 5-diketopiperazine oxytocin antagonists: from concept to clinical candidate for premature labor

Medicinal research reviews, 2011-07, Vol.31 (4), p.576-604

2011

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Sociology of the professions: what it means for podiatry

Journal of foot and ankle research, 2018-06, Vol.11 (1), p.30-n/a

2018

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Charismatic authority in modern healthcare: the case of the ‘diabetes specialist podiatrist’

Sociology of health & illness, 2013-09, Vol.35 (7), p.1080-1094

2013

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Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury

Bioorganic & medicinal chemistry letters, 2019-04, Vol.29 (8), p.995-1000

2019

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Diabetes educator role boundaries in Australia: a documentary analysis

Journal of foot and ankle research, 2017-07, Vol.10 (1), p.28-n/a

2017

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Journal of Foot and Ankle Research: the first ten years

Journal of foot and ankle research, 2018-08, Vol.11 (1), p.44-n/a

2018

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Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist

Bioorganic & medicinal chemistry, 2018-02, Vol.26 (4), p.798-814

2018

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Evidence for current recommendations concerning the management of foot health for people with chronic long‐term conditions: a systematic review

Journal of foot and ankle research, 2017-11, Vol.10 (1), p.51-n/a

2017

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The discovery of GSK221149A: A potent and selective oxytocin antagonist

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.90-94

2008

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UK podiatrists' experiences of podiatry services for people living with arthritis: a qualitative investigation

Journal of foot and ankle research, 2018-06, Vol.11 (1), p.27-n/a, Article 27

2018

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Design of translactam HCMV protease inhibitors as potent antivirals

Medicinal research reviews, 2005-07, Vol.25 (4), p.427-452

Borthwick, Alan D.

2005

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Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1546-1557

2007

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2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency

Journal of medicinal chemistry, 2006-07, Vol.49 (14), p.4159-4170

2006

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2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2579-2582

2005

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2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 2. Synthesis, Chirality, and Pharmacokinetics

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.6956-6969

2005

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Design and Synthesis of Pyrrolidine-5,5‘-trans-Lactams (5-Oxo-hexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral Activity and Plasma Stability

Journal of medicinal chemistry, 2003-10, Vol.46 (21), p.4428-4449

2003

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Use of a novel and highly selective oxytocin receptor antagonist to characterize uterine contractions in the rat

American journal of physiology. Regulatory, integrative and comparative physiology, 2007-07, Vol.293 (1), p.R299-R305

2007

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2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

2,5-diketopiperazines in food and beverages: Taste and bioactivity

Dynamic professional boundaries in the healthcare workforce

Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS Activity and Treatment of Cognitive Dysfunction in Central Neurodegenerative Diseases

A decade of independent prescribing in the UK: a review of progress

Oral Oxytocin Antagonists

Independent prescribing in the UK: insights from the Department of Health Allied Health Professions Medicines Project team

The mystery of the COVID toes – turning evidence‐based medicine on its head

The design of orally bioavailable 2, 5-diketopiperazine oxytocin antagonists: from concept to clinical candidate for premature labor

Sociology of the professions: what it means for podiatry

Charismatic authority in modern healthcare: the case of the ‘diabetes specialist podiatrist’

Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury

Diabetes educator role boundaries in Australia: a documentary analysis

Journal of Foot and Ankle Research: the first ten years

Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist

Evidence for current recommendations concerning the management of foot health for people with chronic long‐term conditions: a systematic review

The discovery of GSK221149A: A potent and selective oxytocin antagonist

UK podiatrists' experiences of podiatry services for people living with arthritis: a qualitative investigation

Design of translactam HCMV protease inhibitors as potent antivirals

Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 2. Synthesis, Chirality, and Pharmacokinetics

Design and Synthesis of Pyrrolidine-5,5‘-trans-Lactams (5-Oxo-hexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral Activity and Plasma Stability

Use of a novel and highly selective oxytocin receptor antagonist to characterize uterine contractions in the rat

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