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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Nature communications, 2016-11, Vol.7 (1), p.13457-13457, Article 13457

2016

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Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

Circulation (New York, N.Y.), 2013-06, Vol.127 (25), p.2523-2534

2013

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Controlling Liquid Crystal Orientations for Programmable Anisotropic Transformations in Cellular Microstructures

Advanced materials (Weinheim), 2021-10, Vol.33 (42), p.e2105024-n/a

2021

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Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

The European respiratory journal, 2020-09, Vol.56 (3), p.2001123

2020

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The unfolded protein response in health and disease

Antioxidants & redox signaling, 2009-09, Vol.11 (9), p.2279-2287

Austin, Richard C

2009

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Interrelationship Between Cardiac Hypertrophy, Heart Failure, and Chronic Kidney Disease: Endoplasmic Reticulum Stress As a Mediator of Pathogenesis

Circulation research, 2011-03, Vol.108 (5), p.629-642

2011

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770

2022

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Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins

Cancer research (Chicago, Ill.), 2023-07, Vol.83 (13), p.2091-2092

2023

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Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity

Scientific reports, 2024-01, Vol.14 (1), p.1805-1805, Article 1805

2024

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MAPping the kinase landscape of macrophage activation

The Journal of biological chemistry, 2018-06, Vol.293 (25), p.9910-9911

2018

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Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death

Toxicology and applied pharmacology, 2018-06, Vol.349, p.1-7

2018

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The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response[S]

Journal of lipid research, 2009-12, Vol.50 (12), p.2486-2501

2009

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GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis

The Journal of pathology, 2016-08, Vol.239 (4), p.411-425

2016

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Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

The Journal of biological chemistry, 2018-09, Vol.293 (38), p.14689-14706

2018

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Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice

The Journal of biological chemistry, 2019-06, Vol.294 (23), p.9037-9047

2019

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Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms

BioFactors (Oxford), 2009-03, Vol.35 (2), p.120-129

2009

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Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy

The Journal of biological chemistry, 2019-05, Vol.294 (19), p.7755-7768

2019

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Regulation of the tumor suppressor PTEN through exosomes: a diagnostic potential for prostate cancer

PloS one, 2013-07, Vol.8 (7), p.e70047-e70047

2013

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Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors

Clinical cancer research, 2021-03, Vol.27 (5), p.1452-1462

2021

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TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease

Cell death & disease, 2021-10, Vol.12 (10), p.921-921, Article 921

2021

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Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism

The Journal of biological chemistry, 2017-01, Vol.292 (4), p.1510-1523

2017

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A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice

Nutrients, 2023-05, Vol.15 (10), p.2410

2023

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GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4)

Hypertension (Dallas, Tex. 1979), 2019-02, Vol.73 (2), p.390-398

2019

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Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice

Circulation (New York, N.Y.), 2005-04, Vol.111 (14), p.1814-1821

2005

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Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Journal of lipid research, 2015-05, Vol.56 (5), p.1025-1033

2015

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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

Controlling Liquid Crystal Orientations for Programmable Anisotropic Transformations in Cellular Microstructures

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

The unfolded protein response in health and disease

Interrelationship Between Cardiac Hypertrophy, Heart Failure, and Chronic Kidney Disease: Endoplasmic Reticulum Stress As a Mediator of Pathogenesis

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins

Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity

MAPping the kinase landscape of macrophage activation

Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response[S]

GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis

Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice

Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms

Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy

Regulation of the tumor suppressor PTEN through exosomes: a diagnostic potential for prostate cancer

Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors

TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease

Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism

A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice

GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4)

Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

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